Protein: NALP7
NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)

Gene: NALP7, NLRP7
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q8WX94

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0010955 - negative regulation of protein processing
GO:0019828 - aspartic-type endopeptidase inhibitor activity
GO:0019966 - interleukin-1 binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1263202

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

19

Small-scale

0.653

High

984002

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

Small-scale

0.628

High

886442

NALP5
NACHT, LRR and PYD domains-containing protein 5

1

17

Small-scale

0.618

High

1263222

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

20

Small-scale

0.618

High

629163

ZA2G
Zinc-alpha-2-glycoprotein

1

2

High-throughput

0.553

High

1263211

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

16

High-throughput

0.553

High

353012

IL1B
Interleukin-1 beta

1

2

Small-scale

0.515

High

667480

CASP1
Caspase-1

1

20

Small-scale

0.515

High

1169019

DEFI8
Differentially expressed in FDCP 8 homolog

1

1

High-throughput

0.489

High

62690

OOEP
Oocyte-expressed protein homolog

1

5

Small-scale

0.479

High

117191

DX39A
ATP-dependent RNA helicase DDX39A

1

3

High-throughput

0.479

High

195500

DHX15
ATP-dependent RNA helicase DHX15

1

3

High-throughput

0.479

High

398382

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.479

High

400608

RLA2
Large ribosomal subunit protein P2

1

1

High-throughput

0.479

High

416484

S10A9
Protein S100-A9

1

4

High-throughput

0.479

High

418497

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

427630

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

443692

VIME
Vimentin

1

8

High-throughput

0.479

High

445481

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.479

High

449327

LEG1
Galectin-1

1

1

High-throughput

0.479

High

578046

RL17
Large ribosomal subunit protein uL22

1

1

High-throughput

0.479

High

609969

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.479

High

637005

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

647147

1433T
14-3-3 protein theta

1

2

High-throughput

0.479

High

656877

GSTM2
Glutathione S-transferase Mu 2

1

2

High-throughput

0.479

High

678481

S10A7
Protein S100-A7

1

4

High-throughput

0.479

High

683119

CASPE
Caspase-14

1

20

High-throughput

0.479

High

685738

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.479

High

737945

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

4

High-throughput

0.479

High

757696

IF4A3
Eukaryotic initiation factor 4A-III

1

4

High-throughput

0.479

High

806612

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.479

High

825225

RL34
Large ribosomal subunit protein eL34

1

1

High-throughput

0.479

High

892862

IF4A1
Eukaryotic initiation factor 4A-I

1

3

High-throughput

0.479

High

900213

RL37A
Large ribosomal subunit protein eL43

1

1

High-throughput

0.479

High

906045

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

High-throughput

0.479

High

906546

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

4

High-throughput

0.479

High

923127

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.479

High

931301

YBOX1
Y-box-binding protein 1

1

2

High-throughput

0.479

High

962243

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.479

High

992861

SRSF1
Serine/arginine-rich splicing factor 1

1

2

High-throughput

0.479

High

994265

DHX9
ATP-dependent RNA helicase A

1

3

High-throughput

0.479

High

1019848

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.479

High

1084348

SRSF7
Serine/arginine-rich splicing factor 7

1

3

High-throughput

0.479

High

1123110

KHDC3
KH domain-containing protein 3

1

5

Small-scale

0.479

High

1125333

FILA2
Filaggrin-2

1

4

High-throughput

0.479

High

1183951

DHX30
ATP-dependent RNA helicase DHX30

1

3

High-throughput

0.479

High

1263206

DDX17
Probable ATP-dependent RNA helicase DDX17

1

2

High-throughput

0.479

High

1263214

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

2

High-throughput

0.479

High

1263215

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.479

High

1263217

TLE6
Transducin-like enhancer protein 6

1

8

Small-scale

0.479

High

1263218

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.479

High

1263220

RNC
Ribonuclease 3

1

1

High-throughput

0.479

High

1263232

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

4

High-throughput

0.479

High

1263233

MORC2
ATPase MORC2

1

1

High-throughput

0.479

High

1263228

FAF1
FAS-associated factor 1

1

6

Small-scale

0.464

High

133587

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

345122

CYTA
Cystatin-A

1

0

High-throughput

0.458

High

358543

CO1A1
Collagen alpha-1(I) chain

1

0

High-throughput

0.458

High

373407

CATA
Catalase

1

0

High-throughput

0.458

High

396267

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

398280

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

0

High-throughput

0.458

High

398919

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.458

High

401012

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

417371

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

428337

TBB5
Tubulin beta chain

1

0

High-throughput

0.458

High

518731

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

531223

EF2
Elongation factor 2

1

0

High-throughput

0.458

High

537975

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

548935

NDKA
Nucleoside diphosphate kinase A

1

0

High-throughput

0.458

High

574393

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

575121

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

614398

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.458

High

616429

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

642484

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.458

High

671681

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

702110

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.458

High

759755

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

760199

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

790483

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

806097

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

806357

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.458

High

814830

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

842589

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

898408

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

898686

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

905691

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

907423

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.458

High

912827

TYB4
Thymosin beta-4

1

0

High-throughput

0.458

High

913654

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

916287

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

916726

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

949520

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.458

High

951671

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

971519

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.458

High

973153

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

989872

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.458

High

993987

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.458

High

1058258

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

High-throughput

0.458

High

1164642

PADI6
Protein-arginine deiminase type-6

1

0

Small-scale

0.458

High

1263203

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.458

High

1263204

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.458

High

1263210

ZBED3
Zinc finger BED domain-containing protein 3

1

0

Small-scale

0.458

High

1263213

ATX2
Ataxin-2

1

0

High-throughput

0.458

High

1263216

DIDO1
Death-inducer obliterator 1

1

0

High-throughput

0.458

High

1263219

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1263227

AGO1
Protein argonaute-1

1

0

High-throughput

0.458

High

1263229

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.458

High

317744

STABP
STAM-binding protein

1

1

Small-scale

0.457

High

180391

MAGB2
Melanoma-associated antigen B2

1

2

High-throughput

0.437

High

202227

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

1

High-throughput

0.437

High

280495

KT33A
Keratin, type I cuticular Ha3-I

1

8

High-throughput

0.437

High

280819

KRT36
Keratin, type I cuticular Ha6

1

8

High-throughput

0.437

High

355159

HBD
Hemoglobin subunit delta

1

1

High-throughput

0.437

High

396776

S10A8
Protein S100-A8

1

3

High-throughput

0.437

High

420863

H2B1J
Histone H2B type 1-J

1

2

High-throughput

0.437

High

432830

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.437

High

476115

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.437

High

518433

ADT3
ADP/ATP translocase 3

1

2

High-throughput

0.437

High

595333

LMNB1
Lamin-B1

1

9

High-throughput

0.437

High

682910

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

2

High-throughput

0.437

High

739208

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.437

High

855153

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

2

High-throughput

0.437

High

936065

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.437

High

943651

KRT83
Keratin, type II cuticular Hb3

1

3

High-throughput

0.437

High

943687

KRT85
Keratin, type II cuticular Hb5

1

4

High-throughput

0.437

High

964036

SRSF2
Serine/arginine-rich splicing factor 2

1

1

High-throughput

0.437

High

980297

K1C17
Keratin, type I cytoskeletal 17

1

8

High-throughput

0.437

High

995997

DSC1
Desmocollin-1

1

3

High-throughput

0.437

High

1019574

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.437

High

1028751

SRSF5
Serine/arginine-rich splicing factor 5

1

1

High-throughput

0.437

High

1055071

KT33B
Keratin, type I cuticular Ha3-II

1

8

High-throughput

0.437

High

1166701

WDR82
WD repeat-containing protein 82

1

6

High-throughput

0.437

High

1192452

K2C1B
Keratin, type II cytoskeletal 1b

1

4

High-throughput

0.437

High

1216235

H2A2B
Histone H2A type 2-B

1

3

High-throughput

0.437

High

1263205

KRT35
Keratin, type I cuticular Ha5

1

8

High-throughput

0.437

High

1263207

H2A1C
Histone H2A type 1-C

1

3

High-throughput

0.437

High

1263208

GCC1
GRIP and coiled-coil domain-containing protein 1

1

2

High-throughput

0.437

High

1263212

H2A1H
Histone H2A type 1-H

1

3

High-throughput

0.437

High

1263221

KRT82
Keratin, type II cuticular Hb2

1

4

High-throughput

0.437

High

1263231

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

1

High-throughput

0.437

High

334252

LDHA
L-lactate dehydrogenase A chain

1

0

High-throughput

0.249

Low

375983

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.249

Low

414646

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.249

Low

546407

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.249

Low

618678

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.249

Low

649633

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

853006

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.249

Low

946578

DCD
Dermcidin

1

0

High-throughput

0.249

Low

951884

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.249

Low

1028260

SBP1
Methanethiol oxidase

1

0

High-throughput

0.249

Low

1074951

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.249

Low

1134459

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

1165468

SBSN
Suprabasin

1

0

High-throughput

0.249

Low

1263209

SPF45
Splicing factor 45

1

0

High-throughput

0.249

Low

1263223

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.249

Low

1263224

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.249

Low

1263225

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

0

High-throughput

0.249

Low

1263226

S30BP
SAP30-binding protein

1

0

High-throughput

0.249

Low

1263230

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024