Protein: SULF2
Extracellular sulfatase Sulf-2 (hSulf-2) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]

Gene: SULF2
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q8IWU5

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0002063 - chondrocyte development
GO:0003094 - glomerular filtration
GO:0004065 - arylsulfatase activity
GO:0005509 - calcium ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549097

GNS
N-acetylglucosamine-6-sulfatase

2

7

High-throughput

0.811

High

1219500

SULF1
Extracellular sulfatase Sulf-1

1

7

High-throughput

0.691

High

159720

CASQ2
Calsequestrin-2

3

3

High-throughput

0.667

High

1044377

PTC1
Protein patched homolog 1

3

1

High-throughput

0.667

High

1069121

PON2
Serum paraoxonase/arylesterase 2

3

1

High-throughput

0.667

High

395127

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.628

High

713116

SDC2
Syndecan-2

2

2

High-throughput

0.628

High

887049

DEF1
Neutrophil defensin 1

2

4

High-throughput

0.628

High

965253

DEF5
Defensin alpha 5

2

4

High-throughput

0.628

High

1034486

OS9
Protein OS-9

2

2

High-throughput

0.628

High

1219529

LRC4C
Leucine-rich repeat-containing protein 4C

2

1

High-throughput

0.628

High

1219507

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.602

High

1219510

TP4AP
Short transient receptor potential channel 4-associated protein

2

0

High-throughput

0.602

High

1219538

DKK3
Dickkopf-related protein 3

2

0

High-throughput

0.602

High

1219503

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

1

High-throughput

0.574

High

968870

NAAA
N-acylethanolamine-hydrolyzing acid amidase

2

6

High-throughput

0.558

High

195718

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

1

High-throughput

0.536

High

254272

LRP4
Low-density lipoprotein receptor-related protein 4

1

2

High-throughput

0.536

High

352171

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.536

High

486287

CCL3
C-C motif chemokine 3

1

5

High-throughput

0.536

High

533004

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.536

High

557188

PGFRA
Platelet-derived growth factor receptor alpha

1

6

High-throughput

0.536

High

561741

CL3L1
C-C motif chemokine 3-like 1

1

5

High-throughput

0.536

High

626190

APC
Adenomatous polyposis coli protein

1

1

High-throughput

0.536

High

680370

SDC4
Syndecan-4

1

2

High-throughput

0.536

High

685267

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

4

High-throughput

0.536

High

882074

EP3B
Epididymal secretory protein E3-beta

1

2

High-throughput

0.536

High

914607

LCN6
Epididymal-specific lipocalin-6

1

2

High-throughput

0.536

High

957624

LRP2
Low-density lipoprotein receptor-related protein 2

1

2

High-throughput

0.536

High

964671

IL5RA
Interleukin-5 receptor subunit alpha

1

4

High-throughput

0.536

High

980438

NOTC2
Neurogenic locus notch homolog protein 2

1

2

High-throughput

0.536

High

1030829

SG2A2
Mammaglobin-A

1

6

High-throughput

0.536

High

1217137

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

3

High-throughput

0.536

High

1219504

SUMF1
Formylglycine-generating enzyme

1

13

High-throughput

0.536

High

1219512

CA054
Uncharacterized protein C1orf54

1

3

High-throughput

0.536

High

1219517

LCFC1
Sperm-egg fusion protein LLCFC1

1

4

High-throughput

0.536

High

1219523

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

3

High-throughput

0.536

High

1219527

SPON1
Spondin-1

1

1

High-throughput

0.536

High

1219533

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

4

High-throughput

0.536

High

1219539

FBLN5
Fibulin-5

1

4

High-throughput

0.536

High

1219541

FBX2
F-box only protein 2

1

10

High-throughput

0.536

High

1219543

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

1

High-throughput

0.536

High

610748

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

0

High-throughput

0.513

High

679264

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

0

High-throughput

0.513

High

834537

TIG1
Retinoic acid receptor responder protein 1

1

0

High-throughput

0.513

High

934289

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.513

High

1166379

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.513

High

1219521

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.513

High

1219526

CAD23
Cadherin-23

1

0

High-throughput

0.513

High

1219530

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

1219537

COMD3
COMM domain-containing protein 3

1

0

High-throughput

0.513

High

1219542

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.513

High

63774

CC85C
Coiled-coil domain-containing protein 85C

1

1

High-throughput

0.489

High

179049

TNC18
Trinucleotide repeat-containing gene 18 protein

1

1

High-throughput

0.489

High

241780

CCD22
Coiled-coil domain-containing protein 22

1

2

High-throughput

0.489

High

244639

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.489

High

257806

SIN3B
Paired amphipathic helix protein Sin3b

1

1

High-throughput

0.489

High

631493

BRD2
Bromodomain-containing protein 2

1

4

High-throughput

0.489

High

1079241

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.489

High

1133230

HECD3
E3 ubiquitin-protein ligase HECTD3

1

3

High-throughput

0.489

High

1162549

TXD11
Thioredoxin domain-containing protein 11

1

6

High-throughput

0.489

High

1185173

G2E3
G2/M phase-specific E3 ubiquitin-protein ligase

1

1

High-throughput

0.489

High

1201526

ZCH18
Zinc finger CCCH domain-containing protein 18

1

2

High-throughput

0.489

High

1219501

UBR1
E3 ubiquitin-protein ligase UBR1

1

1

High-throughput

0.489

High

1219502

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.489

High

1219508

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

1219509

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.489

High

1219516

DCAF5
DDB1- and CUL4-associated factor 5

1

1

High-throughput

0.489

High

1219518

KLH15
Kelch-like protein 15

1

1

High-throughput

0.489

High

1219519

SIN3A
Paired amphipathic helix protein Sin3a

1

1

High-throughput

0.489

High

1219545

SRRM2
Serine/arginine repetitive matrix protein 2

1

2

High-throughput

0.489

High

205639

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

584427

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

1

Small-scale

0.479

High

1219532

TMPS4
Transmembrane protease serine 4

1

5

High-throughput

0.479

High

1170712

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1219513

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1219531

FBX6
F-box only protein 6

1

10

High-throughput

0.437

High

1131924

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.426

High

1219511

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

0

High-throughput

0.328

High

319254

BRD1
Bromodomain-containing protein 1

2

0

High-throughput

0.318

High

165692

SET1A
Histone-lysine N-methyltransferase SETD1A

1

0

High-throughput

0.279

Low

253577

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

0

High-throughput

0.279

Low

422540

CENPB
Major centromere autoantigen B

1

0

High-throughput

0.279

Low

567723

UBF1
Nucleolar transcription factor 1

1

0

High-throughput

0.279

Low

788045

AF9
Protein AF-9

1

0

High-throughput

0.279

Low

947607

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.279

Low

948630

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.279

Low

1063934

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.279

Low

1109049

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

0

High-throughput

0.279

Low

1129327

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1129628

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.279

Low

1161737

KLD10
Kelch domain-containing protein 10

1

0

High-throughput

0.279

Low

1173304

ANKS3
Ankyrin repeat and SAM domain-containing protein 3

1

0

High-throughput

0.279

Low

1204157

COMD2
COMM domain-containing protein 2

1

0

High-throughput

0.279

Low

1219505

SHCBP
SHC SH2 domain-binding protein 1

1

0

High-throughput

0.279

Low

1219506

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

0

High-throughput

0.279

Low

1219515

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.279

Low

1219520

MINT
Msx2-interacting protein

1

0

High-throughput

0.279

Low

1219522

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

1219524

BACH2
Transcription regulator protein BACH2

1

0

High-throughput

0.279

Low

1219525

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.279

Low

1219528

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

0

High-throughput

0.279

Low

1219534

CXXC1
CXXC-type zinc finger protein 1

1

0

High-throughput

0.279

Low

1219535

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

0

High-throughput

0.279

Low

1219536

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.279

Low

1219540

TSYL4
Testis-specific Y-encoded-like protein 4

1

0

High-throughput

0.279

Low

1219544

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

1219546

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.279

Low

1219547

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

1219548

DCAF1
DDB1- and CUL4-associated factor 1

1

0

High-throughput

0.279

Low

1219514

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.269

Low

182819

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024