Protein: CIK1
Spindle pole body-associated protein CIK1 (Chromosome instability and karyogamy protein 1)

Gene: CIK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 74
UniProt ID: Q01649

Gene Ontology (top 5):
GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0000743 - nuclear migration involved in conjugation with cellular fusion
GO:0003777 - microtubule motor activity
GO:0005634 - nucleus
GO:0005816 - spindle pole body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

602059

KAR3
Kinesin-like protein KAR3

12

1

Small-scale

0.984

High

548233

BIK1
Nuclear fusion protein BIK1

2

2

Small-scale

0.595

High

866056

NNF1
Kinetochore-associated protein NNF1

2

0

High-throughput

0.570

High

816974

BIM1
Protein BIM1

2

0

Small-scale

0.569

High

676271

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.500

High

866210

CENPK
Inner kinetochore subunit MCM22

1

0

High-throughput

0.493

High

646074

KIN3
Serine/threonine-protein kinase KIN3

1

0

High-throughput

0.460

High

755283

NUF2
Kinetochore protein NUF2

1

0

High-throughput

0.460

High

779791

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.460

High

813836

MBO1
Gamma tubulin complex adapter SPC72

1

0

Small-scale

0.460

High

817020

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

823222

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

921095

PRS10
26S proteasome subunit RPT4

1

0

High-throughput

0.460

High

1031760

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

1031763

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.460

High

368249

TRP
Tryptophan synthase

1

0

High-throughput

0.458

High

448329

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

464336

OAT
Ornithine aminotransferase

1

0

High-throughput

0.458

High

567726

MSI1
Histone-binding protein MSI1

1

0

High-throughput

0.458

High

666663

AP2
AP-1-like transcription factor YAP2

1

0

High-throughput

0.458

High

692522

GYS2
Glycogen [starch] synthase isoform 2

1

0

High-throughput

0.458

High

707931

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735538

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.458

High

740279

SMI1
Cell wall assembly regulator SMI1

1

0

High-throughput

0.458

High

798024

TYDP1
Tyrosyl-DNA phosphodiesterase 1

1

0

High-throughput

0.458

High

805868

ARO9
Aromatic amino acid aminotransferase 2

1

0

High-throughput

0.458

High

808888

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

836655

GLDS1
Protein GDS1

1

0

High-throughput

0.458

High

850299

SAD1
Pre-mRNA-splicing factor SAD1

1

0

High-throughput

0.458

High

1031759

CUS1
Cold sensitive U2 snRNA suppressor 1

1

0

High-throughput

0.458

High

1031767

DXO1
Decapping and exoribonuclease protein 1

1

0

High-throughput

0.458

High

1031770

GIN4
Serine/threonine-protein kinase GIN4

1

0

High-throughput

0.458

High

1031773

STB3
Protein STB3

1

0

High-throughput

0.458

High

524876

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

527454

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

545938

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

819538

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

815048

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.439

High

1031765

VPS20
Vacuolar protein sorting-associated protein 20

1

1

High-throughput

0.439

High

1031764

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.279

Low

826372

SGN1
RNA-binding protein SGN1

1

0

High-throughput

0.269

Low

737338

CDC12
Cell division control protein 12

1

0

High-throughput

0.265

Low

367395

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

531385

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.261

Low

737022

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

758135

CASP
Protein CASP

1

0

High-throughput

0.251

Low

817751

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

849836

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

918759

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

919243

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.251

Low

924481

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.251

Low

999587

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

1031758

MDM1
Structural protein MDM1

1

0

High-throughput

0.251

Low

1031766

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

661734

VAN1
Mannan polymerase I complex VAN1 subunit

1

0

High-throughput

0.249

Low

662896

RIT1
tRNA A64-2'-O-ribosylphosphate transferase

1

0

High-throughput

0.249

Low

733788

AFG1
Protein AFG1

1

0

High-throughput

0.249

Low

737201

HYM1
Protein HYM1

1

0

High-throughput

0.249

Low

757615

TGL1
Sterol esterase TGL1

1

0

High-throughput

0.249

Low

757822

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.249

Low

780930

ANR2
Uncharacterized protein ANR2

1

0

High-throughput

0.249

Low

803478

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

0

High-throughput

0.249

Low

850625

OSW7
Outer spore wall protein 7

1

0

High-throughput

0.249

Low

864672

SNX4
Sorting nexin-4

1

0

High-throughput

0.249

Low

866193

SGM1
Protein SGM1

1

0

High-throughput

0.249

Low

873839

SYEM
Glutamate--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

1031761

LPE10
Mitochondrial inner membrane magnesium transporter MFM1

1

0

High-throughput

0.249

Low

1031762

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

0

High-throughput

0.249

Low

1031768

ECM30
Protein ECM30

1

0

High-throughput

0.249

Low

1031772

PRP46
Pre-mRNA-splicing factor PRP46

1

0

High-throughput

0.249

Low

1031774

DFM1
DER1-like family member protein 1

1

0

High-throughput

0.249

Low

824522

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low

1031769

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low

1031771

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025