Protein: PLPL1
Omega-hydroxyceramide transacylase (EC 2.3.1.296) (Patatin-like phospholipase domain-containing protein 1)

Gene: PLPL1, PNPLA1
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q8N8W4

Gene Ontology (top 5):
GO:0004806 - triacylglycerol lipase activity
GO:0005737 - cytoplasm
GO:0005811 - lipid droplet
GO:0016020 - membrane
GO:0016747 - acyltransferase activity, transferring groups other than amino-acyl groups

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1220650

RN123
E3 ubiquitin-protein ligase RNF123

3

0

High-throughput

0.638

High

155782

TXND9
Thioredoxin domain-containing protein 9

2

2

High-throughput

0.611

High

1331403

TCPW
T-complex protein 1 subunit zeta-2

3

7

High-throughput

0.609

High

1212803

UBR4
E3 ubiquitin-protein ligase UBR4

2

0

High-throughput

0.585

High

1331405

NIF3L
NIF3-like protein 1

2

0

High-throughput

0.585

High

1007143

TCPB
T-complex protein 1 subunit beta

2

7

High-throughput

0.574

High

882033

TCPG
T-complex protein 1 subunit gamma

2

6

High-throughput

0.558

High

1331406

PDCL3
Phosducin-like protein 3

1

2

High-throughput

0.536

High

1192948

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

0

High-throughput

0.513

High

1331408

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

0

High-throughput

0.513

High

610772

TCPA
T-complex protein 1 subunit alpha

1

5

High-throughput

0.489

High

1331407

CHM1A
Charged multivesicular body protein 1a

1

1

High-throughput

0.489

High

1331411

CHMP3
Charged multivesicular body protein 3

1

1

High-throughput

0.489

High

1103636

PHLP
Phosducin-like protein

1

2

High-throughput

0.479

High

1331404

UBAC1
Ubiquitin-associated domain-containing protein 1

3

0

High-throughput

0.347

High

999383

HBB
Hemoglobin subunit beta

2

0

High-throughput

0.318

High

1331410

TM160
Transmembrane protein 160

2

0

High-throughput

0.318

High

66240

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.279

Low

1230783

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.279

Low

1331409

UQCC1
Ubiquinol-cytochrome c reductase complex assembly factor 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025