Protein: RABX5
Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)

Gene: RABX5, RABGEF1
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q9UJ41

Gene Ontology (top 5):
GO:0001933 - negative regulation of protein phosphorylation
GO:0002686 - negative regulation of leukocyte migration
GO:0003677 - DNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476534

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

12

7

Small-scale

0.975

High

1070182

RABE1
Rab GTPase-binding effector protein 1

10

5

Small-scale

0.975

High

592565

RAB5A
Ras-related protein Rab-5A

4

20

Small-scale

0.878

High

1355934

RAB21
Ras-related protein Rab-21

3

20

Small-scale

0.875

High

1355930

RABX5
Rab5 GDP/GTP exchange factor

3

7

Small-scale

0.850

High

1332063

RABE2
Rab GTPase-binding effector protein 2

2

5

High-throughput

0.811

High

592053

RAB4A
Ras-related protein Rab-4A

2

9

High-throughput

0.789

High

872228

RD23A
UV excision repair protein RAD23 homolog A

2

4

High-throughput

0.783

High

924431

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

4

High-throughput

0.783

High

914438

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.754

High

683797

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.712

High

905227

1433G
14-3-3 protein gamma

5

20

High-throughput

0.712

High

475229

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

7

Small-scale

0.692

High

1317478

TRI54
Tripartite motif-containing protein 54

3

11

High-throughput

0.675

High

1286322

Q96C32
UBC protein

1

7

High-throughput

0.665

High

927632

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.662

High

1254527

CCHCR
Coiled-coil alpha-helical rod protein 1

3

1

High-throughput

0.653

High

982599

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

349717

RASH
GTPase HRas

1

14

Small-scale

0.647

High

849479

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

1

Small-scale

0.647

High

895944

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

1

Small-scale

0.647

High

1355936

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

3

0

High-throughput

0.646

High

311018

SNAPN
SNARE-associated protein Snapin

3

0

High-throughput

0.639

High

1061896

SLMAP
Sarcolemmal membrane-associated protein

4

2

High-throughput

0.638

High

161731

GAK
Cyclin-G-associated kinase

2

1

High-throughput

0.628

High

981045

HGFA
Hepatocyte growth factor activator

2

2

High-throughput

0.628

High

1020977

TRAF2
TNF receptor-associated factor 2

2

3

High-throughput

0.628

High

1036368

BIRC2
Baculoviral IAP repeat-containing protein 2

2

1

High-throughput

0.628

High

1078063

HERC1
Probable E3 ubiquitin-protein ligase HERC1

2

1

High-throughput

0.628

High

1201938

TAXB1
Tax1-binding protein 1

2

2

High-throughput

0.628

High

1290091

RNF31
E3 ubiquitin-protein ligase RNF31

2

1

High-throughput

0.628

High

1291931

OTUD5
OTU domain-containing protein 5

2

1

High-throughput

0.628

High

1317096

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

2

3

High-throughput

0.628

High

1327713

SHRPN
Sharpin

2

1

High-throughput

0.628

High

1330038

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

2

2

High-throughput

0.628

High

1355932

GGA1
ADP-ribosylation factor-binding protein GGA1

2

1

Small-scale

0.625

High

339105

EGFR
Epidermal growth factor receptor

2

9

Small-scale

0.621

High

844787

RAB5C
Ras-related protein Rab-5C

1

20

High-throughput

0.618

High

1355935

RB22A
Ras-related protein Rab-22A

1

20

Small-scale

0.618

High

1133668

CC183
Coiled-coil domain-containing protein 183

3

2

High-throughput

0.609

High

1206112

RASL3
RAS protein activator like-3

2

1

High-throughput

0.606

High

1229734

SPART
Spartin

2

1

High-throughput

0.606

High

1289574

HOOK2
Protein Hook homolog 2

2

4

High-throughput

0.606

High

1311972

TCHP
Trichoplein keratin filament-binding protein

2

5

High-throughput

0.606

High

1348424

ABI2
Abl interactor 2

2

7

High-throughput

0.606

High

1355931

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

10

High-throughput

0.606

High

584495

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

0

High-throughput

0.602

High

1057131

EPN4
Clathrin interactor 1

2

0

High-throughput

0.602

High

1219613

UBR1
E3 ubiquitin-protein ligase UBR1

2

0

High-throughput

0.602

High

1346348

EXOC1
Exocyst complex component 1

2

0

High-throughput

0.602

High

1354597

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

0

High-throughput

0.602

High

1355937

RNF11
RING finger protein 11

2

0

High-throughput

0.593

High

1039354

DCTN2
Dynactin subunit 2

2

0

High-throughput

0.580

High

1083039

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.580

High

1285092

ARRD3
Arrestin domain-containing protein 3

2

0

High-throughput

0.580

High

1287752

GASP2
G-protein coupled receptor-associated sorting protein 2

2

0

High-throughput

0.580

High

1291386

CPNE2
Copine-2

2

1

High-throughput

0.574

High

1336179

CPNE5
Copine-5

2

1

High-throughput

0.574

High

1306357

THIOM
Thioredoxin, mitochondrial

1

4

High-throughput

0.573

High

1318675

TRI15
E3 ubiquitin-protein ligase TRIM15

1

6

High-throughput

0.573

High

1202611

SESD1
SEC14 domain and spectrin repeat-containing protein 1

2

3

High-throughput

0.553

High

1235898

ANR29
Ankyrin repeat domain-containing protein 29

2

2

High-throughput

0.553

High

1291531

THOC1
THO complex subunit 1

1

0

High-throughput

0.549

High

1318998

CIPC
CLOCK-interacting pacemaker

1

0

High-throughput

0.549

High

147828

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

1

High-throughput

0.536

High

484894

ZTRF1
Zinc finger TRAF-type-containing protein 1

2

0

High-throughput

0.528

High

1051503

DCTN1
Dynactin subunit 1

1

3

High-throughput

0.515

High

237914

AP180
Clathrin coat assembly protein AP180

1

0

High-throughput

0.513

High

975100

CAV1
Caveolin-1

1

0

High-throughput

0.513

High

1355939

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

1202659

MON1A
Vacuolar fusion protein MON1 homolog A

1

2

Small-scale

0.501

High

1330432

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.501

High

742594

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

130306

BT3A1
Butyrophilin subfamily 3 member A1

1

4

High-throughput

0.489

High

362039

FIBG
Fibrinogen gamma chain

1

1

High-throughput

0.489

High

639118

S100P
Protein S100-P

1

2

High-throughput

0.489

High

122246

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

1

High-throughput

0.479

High

126177

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

4

High-throughput

0.479

High

181568

CLOCK
Circadian locomoter output cycles protein kaput

1

4

High-throughput

0.479

High

370663

ESR1
Estrogen receptor

1

3

Small-scale

0.479

High

385682

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

647362

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

659082

MK01
Mitogen-activated protein kinase 1

1

4

Small-scale

0.479

High

684381

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

780284

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

882628

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

5

High-throughput

0.479

High

898216

MAX
Protein max

1

3

High-throughput

0.479

High

1050171

GIT2
ARF GTPase-activating protein GIT2

1

1

High-throughput

0.479

High

1067483

EEA1
Early endosome antigen 1

1

2

Small-scale

0.479

High

1122627

CCD93
Coiled-coil domain-containing protein 93

1

1

High-throughput

0.479

High

1160300

PKN3
Serine/threonine-protein kinase N3

1

1

High-throughput

0.479

High

1172179

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1188438

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1205149

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

2

High-throughput

0.479

High

1252334

GOGA5
Golgin subfamily A member 5

1

1

High-throughput

0.479

High

1285385

PF21A
PHD finger protein 21A

1

1

High-throughput

0.479

High

1302570

CRBN
Protein cereblon

1

1

Small-scale

0.479

High

1317809

NUF2
Kinetochore protein Nuf2

1

6

High-throughput

0.479

High

1342349

HM20A
High mobility group protein 20A

1

1

High-throughput

0.479

High

88050

D3DUQ6
TEA domain family member 4 isoform 1

1

1

High-throughput

0.470

High

66320

WASH1
WASH complex subunit 1

1

0

High-throughput

0.460

High

471669

TFPT
TCF3 fusion partner

1

0

High-throughput

0.458

High

685327

L1CAM
Neural cell adhesion molecule L1

1

0

Small-scale

0.458

High

792067

HD
Huntingtin

1

0

High-throughput

0.458

High

1118377

GRAP1
GRIP1-associated protein 1

1

0

High-throughput

0.458

High

1137657

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.458

High

1157627

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

1190421

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.458

High

1289773

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.458

High

1295161

VPS50
Syndetin

1

0

High-throughput

0.458

High

1330358

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

0

Small-scale

0.458

High

1183833

MON1B
Vacuolar fusion protein MON1 homolog B

1

2

Small-scale

0.457

High

1048732

DGCR6
Protein DGCR6

1

1

High-throughput

0.439

High

1075223

TEAD4
Transcriptional enhancer factor TEF-3

1

1

High-throughput

0.439

High

1155886

PHLB3
Pleckstrin homology-like domain family B member 3

1

2

High-throughput

0.437

High

1355940

X5DP20
DiGeorge syndrome critical region 6 isoform D

1

1

High-throughput

0.417

High

1065210

DAZP2
DAZ-associated protein 2

3

0

High-throughput

0.352

High

204454

MS18B
Protein Mis18-beta

3

0

High-throughput

0.340

High

1222770

IHO1
Interactor of HORMAD1 protein 1

2

0

High-throughput

0.316

High

1307170

SSX3
Protein SSX3

2

0

High-throughput

0.316

High

1355938

EMIL1
EMILIN-1

2

0

High-throughput

0.316

High

1309452

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.304

High

1120661

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

0

High-throughput

0.299

High

946452

EREP3
Protein ENTREP3

1

0

High-throughput

0.279

Low

1102665

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1128880

TMM31
Transmembrane protein 31

1

0

High-throughput

0.279

Low

1170059

TLCD5
TLC domain-containing protein 5

1

0

High-throughput

0.279

Low

1170256

R9BP
Regulator of G-protein signaling 9-binding protein

1

0

High-throughput

0.279

Low

1224020

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1298735

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

1299913

CC85A
Coiled-coil domain-containing protein 85A

1

0

High-throughput

0.279

Low

81771

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

317533

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.249

Low

1299017

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.249

Low

1336167

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.249

Low

1342234

TUFT1
Tuftelin

1

0

High-throughput

0.249

Low

1355933

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

1239879

GOLM1
Golgi membrane protein 1

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024