Protein: TLR1
Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281)

Gene: TLR1
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q15399

Gene Ontology (top 5):
GO:0001774 - microglial cell activation
GO:0002224 - toll-like receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

252351

TLR2
Toll-like receptor 2

4

14

Small-scale

0.885

High

1148239

TLR6
Toll-like receptor 6

3

15

Small-scale

0.843

High

1148235

TLR10
Toll-like receptor 10

2

15

Small-scale

0.743

High

1148226

COL12
Collectin-12

1

6

High-throughput

0.691

High

126313

TLR4
Toll-like receptor 4

1

17

Small-scale

0.665

High

1148224

TLR1
Toll-like receptor 1

1

14

Small-scale

0.653

High

188592

SIGL5
Sialic acid-binding Ig-like lectin 5

1

20

Small-scale

0.618

High

1148232

SIG10
Sialic acid-binding Ig-like lectin 10

1

20

Small-scale

0.618

High

1148241

SIGL9
Sialic acid-binding Ig-like lectin 9

1

20

Small-scale

0.618

High

1148227

TM214
Transmembrane protein 214

2

3

High-throughput

0.611

High

1148229

A16A1
Aldehyde dehydrogenase family 16 member A1

2

1

High-throughput

0.611

High

1148234

CNPY3
Protein canopy homolog 3

2

9

High-throughput

0.611

High

1148240

DEOC
Deoxyribose-phosphate aldolase

2

1

High-throughput

0.558

High

287561

LRP6
Low-density lipoprotein receptor-related protein 6

1

1

High-throughput

0.536

High

1148231

MUCL1
Mucin-like protein 1

1

0

High-throughput

0.513

High

1148233

MYD88
Myeloid differentiation primary response protein MyD88

1

17

Small-scale

0.506

High

1148230

S11IP
Serine/threonine-protein kinase 11-interacting protein

1

20

High-throughput

0.489

High

1148237

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.489

High

175370

PLXB2
Plexin-B2

1

1

High-throughput

0.479

High

573488

ENPL
Endoplasmin

1

4

Small-scale

0.479

High

832725

BCL6
B-cell lymphoma 6 protein

1

2

Small-scale

0.479

High

946660

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

3

Small-scale

0.479

High

1148228

MAVS
Mitochondrial antiviral-signaling protein

1

2

High-throughput

0.479

High

1148238

TBC24
TBC1 domain family member 24

1

1

High-throughput

0.479

High

532601

CH60
60 kDa heat shock protein, mitochondrial

1

4

Small-scale

0.457

High

637529

FLNA
Filamin-A

1

5

Small-scale

0.457

High

1090406

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

5

Small-scale

0.457

High

1148236

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

2

Small-scale

0.457

High

1148225

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

717089

ECHM
Enoyl-CoA hydratase, mitochondrial

1

1

Small-scale

0.417

High


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Last updated: 11Aug2025