Protein: ZZZ3
ZZ-type zinc finger-containing protein 3

Gene: ZZZ3
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q8IYH5

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006325 - chromatin organization
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1223165

KAT2A
Histone acetyltransferase KAT2A

5

3

Small-scale

0.909

High

1223191

CSR2B
Cysteine-rich protein 2-binding protein

4

3

Small-scale

0.881

High

266382

TAD2A
Transcriptional adapter 2-alpha

4

3

Small-scale

0.867

High

1223166

KAT2B
Histone acetyltransferase KAT2B

2

3

High-throughput

0.754

High

1223173

SGF29
SAGA-associated factor 29

8

1

Small-scale

0.750

High

903359

WDR5
WD repeat-containing protein 5

6

1

High-throughput

0.737

High

267665

TADA3
Transcriptional adapter 3

5

1

High-throughput

0.714

High

1223197

MBIP1
MAP3K12-binding inhibitory protein 1

5

1

High-throughput

0.714

High

1223210

YETS2
YEATS domain-containing protein 2

3

2

Small-scale

0.640

High

573017

PRS6A
26S proteasome regulatory subunit 6A

3

0

High-throughput

0.638

High

898964

PSME3
Proteasome activator complex subunit 3

3

0

High-throughput

0.638

High

1223214

CARD8
Caspase recruitment domain-containing protein 8

3

0

High-throughput

0.638

High

1223189

IKZF5
Zinc finger protein Pegasus

2

1

High-throughput

0.628

High

1198559

TAD2B
Transcriptional adapter 2-beta

1

3

High-throughput

0.618

High

1223208

RCOR1
REST corepressor 1

1

1

High-throughput

0.618

High

966165

NC2B
Protein Dr1

2

2

High-throughput

0.611

High

1173349

RFPLB
Ret finger protein-like 4B

3

1

High-throughput

0.609

High

1020792

TRAF2
TNF receptor-associated factor 2

2

1

High-throughput

0.606

High

638342

RBTN2
Rhombotin-2

2

0

High-throughput

0.602

High

796234

MAGAA
Melanoma-associated antigen 10

2

0

High-throughput

0.602

High

1152351

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

232309

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.586

High

1038520

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.586

High

995033

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.580

High

1127558

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.580

High

1223177

ASPP1
Apoptosis-stimulating of p53 protein 1

2

0

High-throughput

0.580

High

1223186

CAD19
Cadherin-19

2

1

High-throughput

0.558

High

891890

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.536

High

900048

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

1

High-throughput

0.536

High

554476

GATA1
Erythroid transcription factor

1

0

High-throughput

0.518

High

1223156

TRI22
E3 ubiquitin-protein ligase TRIM22

1

0

High-throughput

0.518

High

1223160

ZN513
Zinc finger protein 513

1

0

High-throughput

0.518

High

1223167

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.518

High

1223170

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

0

High-throughput

0.518

High

1223175

ZN496
Zinc finger protein 496

1

0

High-throughput

0.518

High

1223176

MAML3
Mastermind-like protein 3

1

0

High-throughput

0.518

High

1223188

GO45
Golgin-45

1

0

High-throughput

0.518

High

1223206

ZN212
Zinc finger protein 212

1

0

High-throughput

0.518

High

1223221

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.518

High

622960

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.513

High

641853

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.513

High

941139

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.513

High

1029274

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1050705

FHL2
Four and a half LIM domains protein 2

1

0

High-throughput

0.513

High

1087250

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1223158

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.513

High

1223164

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1223172

ZN653
Zinc finger protein 653

1

0

High-throughput

0.513

High

1223195

DPOE4
DNA polymerase epsilon subunit 4

1

0

High-throughput

0.513

High

1223213

RUVB2
RuvB-like 2

1

0

High-throughput

0.513

High

1223217

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.513

High

1223159

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

3

High-throughput

0.494

High

1223185

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

1

High-throughput

0.494

High

68298

P20L1
PHD finger protein 20-like protein 1

1

2

High-throughput

0.479

High

165693

SET1A
Histone-lysine N-methyltransferase SETD1A

1

3

High-throughput

0.479

High

267779

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

2

High-throughput

0.479

High

316933

KLF8
Krueppel-like factor 8

1

2

High-throughput

0.479

High

347288

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379599

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

692160

ELF1
ETS-related transcription factor Elf-1

1

1

High-throughput

0.479

High

740552

PPARG
Peroxisome proliferator-activated receptor gamma

1

1

High-throughput

0.479

High

749665

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

808762

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

848252

HCFC1
Host cell factor 1

1

3

High-throughput

0.479

High

869492

ATN1
Atrophin-1

1

1

High-throughput

0.479

High

884203

KLF3
Krueppel-like factor 3

1

2

High-throughput

0.479

High

975283

KMT2A
Histone-lysine N-methyltransferase 2A

1

3

High-throughput

0.479

High

1070739

RBBP5
Retinoblastoma-binding protein 5

1

2

High-throughput

0.479

High

1083673

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.479

High

1158974

EDC4
Enhancer of mRNA-decapping protein 4

1

1

High-throughput

0.479

High

1223163

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1223180

ELF4
ETS-related transcription factor Elf-4

1

1

High-throughput

0.479

High

1223182

PHF20
PHD finger protein 20

1

2

High-throughput

0.479

High

1223184

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

1223193

TAF9B
Transcription initiation factor TFIID subunit 9B

1

1

High-throughput

0.479

High

1223199

CXXC1
CXXC-type zinc finger protein 1

1

2

High-throughput

0.479

High

1223202

RERE
Arginine-glutamic acid dipeptide repeats protein

1

3

High-throughput

0.479

High

1223203

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

3

High-throughput

0.479

High

1223211

KMT2B
Histone-lysine N-methyltransferase 2B

1

3

High-throughput

0.479

High

1223212

SET1B
Histone-lysine N-methyltransferase SETD1B

1

3

High-throughput

0.479

High

1223218

KLF12
Krueppel-like factor 12

1

2

High-throughput

0.479

High

1223219

HCFC2
Host cell factor 2

1

3

High-throughput

0.479

High

932252

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.470

High

183135

KDM6A
Lysine-specific demethylase 6A

1

0

High-throughput

0.458

High

266490

SUPT3
Transcription initiation protein SPT3 homolog

1

0

High-throughput

0.458

High

297920

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.458

High

387076

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

546006

MYOD1
Myoblast determination protein 1

1

0

High-throughput

0.458

High

632810

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

668819

PML
Protein PML

1

0

High-throughput

0.458

High

782593

HNF4A
Hepatocyte nuclear factor 4-alpha

1

0

High-throughput

0.458

High

826313

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.458

High

917572

H4
Histone H4

1

0

High-throughput

0.458

High

963644

E2F1
Transcription factor E2F1

1

0

High-throughput

0.458

High

966260

TFAP4
Transcription factor AP-4

1

0

Small-scale

0.458

High

1019018

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1060327

NFIX
Nuclear factor 1 X-type

1

0

High-throughput

0.458

High

1188168

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.458

High

1221557

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1222458

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1223162

SP20H
Transcription factor SPT20 homolog

1

0

High-throughput

0.458

High

1223168

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1223169

TADA1
Transcriptional adapter 1

1

0

High-throughput

0.458

High

1223174

MCRS1
Microspherule protein 1

1

0

High-throughput

0.458

High

1223183

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1223190

KAT8
Histone acetyltransferase KAT8

1

0

High-throughput

0.458

High

1223192

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.458

High

1223198

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1223200

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.458

High

1223201

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.458

High

1223205

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.458

High

1223207

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1223209

ZN608
Zinc finger protein 608

1

0

High-throughput

0.458

High

1223216

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

1223220

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.458

High

1140599

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

1223215

WDR37
WD repeat-containing protein 37

1

2

High-throughput

0.437

High

1223178

Q96KY9
CDH19 protein

1

1

High-throughput

0.407

High

871865

BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic

2

0

High-throughput

0.328

High

1086972

KAT1
Kynurenine--oxoglutarate transaminase 1

2

0

High-throughput

0.328

High

1223161

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.328

High

1223194

PFD4
Prefoldin subunit 4

2

0

High-throughput

0.328

High

1223187

CARD9
Caspase recruitment domain-containing protein 9

2

0

High-throughput

0.316

High

1223196

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1200941

F124A
Protein FAM124A

1

0

High-throughput

0.299

High

515899

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.279

Low

1080876

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.279

Low

1223157

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

0

High-throughput

0.279

Low

1223179

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

1223181

DHB14
17-beta-hydroxysteroid dehydrogenase 14

1

0

High-throughput

0.279

Low

1223204

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.265

Low

1130305

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.261

Low

1020380

EPS8
Epidermal growth factor receptor kinase substrate 8

1

0

High-throughput

0.251

Low

338677

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.249

Low

900201

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.249

Low

1188542

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1223171

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024