Protein: FOXO4
Forkhead box protein O4 (Fork head domain transcription factor AFX1)

Gene: FOXO4
Organism: Homo sapiens
Interactions: 34
UniProt ID: P98177

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003676 - nucleic acid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

958169

CBP
CREB-binding protein

4

20

Small-scale

0.896

High

958162

REL
Proto-oncogene c-Rel

1

9

High-throughput

0.740

High

958164

FOXO1
Forkhead box protein O1

1

17

High-throughput

0.691

High

958161

MDM2
E3 ubiquitin-protein ligase Mdm2

3

4

Small-scale

0.678

High

681791

AKT1
RAC-alpha serine/threonine-protein kinase

3

11

Small-scale

0.670

High

904445

1433G
14-3-3 protein gamma

3

20

High-throughput

0.662

High

958163

1433F
14-3-3 protein eta

3

20

High-throughput

0.662

High

958160

FOXO4
Forkhead box protein O4

1

16

High-throughput

0.646

High

683962

1433S
14-3-3 protein sigma

2

20

High-throughput

0.631

High

683267

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

716994

CTNB1
Catenin beta-1

2

10

Small-scale

0.584

High

958170

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

8

Small-scale

0.584

High

958171

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

12

Small-scale

0.578

High

68647

FOXO6
Forkhead box protein O6

1

16

High-throughput

0.575

High

162631

XPO1
Exportin-1

1

9

Small-scale

0.561

High

958166

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

Small-scale

0.561

High

958172

NLK
Serine/threonine-protein kinase NLK

1

5

Small-scale

0.561

High

380765

S100B
Protein S100-B

1

6

High-throughput

0.536

High

764366

FEN1
Flap endonuclease 1

1

1

High-throughput

0.536

High

926923

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.536

High

958165

SMAD4
Mothers against decapentaplegic homolog 4

1

18

Small-scale

0.534

High

174806

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

7

Small-scale

0.515

High

559653

H12
Histone H1.2

1

1

High-throughput

0.515

High

950142

SMAD3
Mothers against decapentaplegic homolog 3

1

18

Small-scale

0.515

High

369407

ESR1
Estrogen receptor

1

20

Small-scale

0.501

High

386528

P53
Cellular tumor antigen p53

1

12

Small-scale

0.501

High

509932

VDR
Vitamin D3 receptor

1

20

Small-scale

0.479

High

557093

PGFRA
Platelet-derived growth factor receptor alpha

1

4

Small-scale

0.479

High

909442

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.479

High

958167

CSN6
COP9 signalosome complex subunit 6

1

4

Small-scale

0.479

High

958168

COP1
E3 ubiquitin-protein ligase COP1

1

10

Small-scale

0.479

High

868141

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

958173

FBX7
F-box only protein 7

1

0

Small-scale

0.458

High


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Last updated: 15 Jul 2024