HitPredict

Interactor 1: MSI4 (O22607)
WD-40 repeat-containing protein MSI4 (Altered cold-responsive gene 1 protein) (Nucleosome remodeling factor complex component 4) (Protein MULTICOPY SUPPRESSOR OF IRA1 4) (AtMSI4)
Gene: MSI4

Interactor 2: TPL (Q94AI7)
Protein TOPLESS (WUS-interacting protein 1)
Gene: TPL

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22065421
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 507 At			1 1131
+	Hs
		964797 WDR5_HUMAN (4-365): 1.99e-52: 182: 10.48		WDR5_HUMAN (593-904): 8.78e-51: 184: 14.29
+	Hs
		992773 RBBP7_HUMAN (51-494): 1.89e-87: 276: 32.17		RACK1_HUMAN (386-586): 8.2e-16: 81.7: 23.47
+	Hs
		965071 WDR5_HUMAN (4-365): 1.99e-52: 182: 10.48		WDR5B_HUMAN (186-535): 2.67e-45: 168: 13.48
+	Hs
		965276 WDR5_HUMAN (4-365): 1.99e-52: 182: 10.48		NLE1_HUMAN (867-1127): 7.63e-43: 165: 13.09
+	Hs
		964894 WDR5_HUMAN (4-365): 1.99e-52: 182: 10.48		TBL3_HUMAN (166-535): 7.1e-38: 155: 12.44
+	Hs
		845264 WDR5_HUMAN (4-365): 1.99e-52: 182: 10.48		LIS1_HUMAN (293-538): 1.04e-35: 143: 16.38
+	Ce
		1018621 LIN53_CAEEL (291-507): 2.11e-34: 135: 20.44		GBLP_CAEEL (366-667): 1.12e-52: 189: 20.67
+	Hs
		964891 RBBP4_HUMAN (291-507): 9.51e-33: 131: 20.35		WDR5_HUMAN (593-904): 8.78e-51: 184: 14.29
+	Mm
		988931 LIS1_MOUSE (37-323): 2.99e-35: 137: 12.42		LIS1_MOUSE (171-538): 7.23e-48: 178: 13.74
+	Sp
		1068482 TUP11_SCHPO (7-417): 4.41e-62: 215: 17.78		TUP11_SCHPO (950-1131): 3.23e-20: 98.2: 9.09
+	Hs
		845250 LIS1_HUMAN (37-323): 3.58e-35: 137: 12.42		LIS1_HUMAN (293-538): 1.04e-35: 143: 16.38
+	Hs
		261440 TBL1X_HUMAN (145-506): 3.22e-59: 206: 14.55		TBL1R_HUMAN (1004-1115): 5.43e-09: 62: 13.04
+	Hs
		964829 WDR5_HUMAN (4-365): 1.99e-52: 182: 10.48		RACK1_HUMAN (386-586): 8.2e-16: 81.7: 23.47
+	Dm
		1463899 WDS_DROME (75-365): 1.6e-51: 181: 13.61		WDS_DROME (219-387): 9.82e-10: 63.9: 8.72
+	Hs
		845282 LIS1_HUMAN (37-323): 3.58e-35: 137: 12.42		RACK1_HUMAN (386-586): 8.2e-16: 81.7: 23.47
+	Hs
		845346 LIS1_HUMAN (37-323): 3.58e-35: 137: 12.42		KTNB1_HUMAN (746-1034): 2.96e-14: 79.4: 18.21
+	Hs
		992707 RBBP4_HUMAN (291-507): 9.51e-33: 131: 20.35		RACK1_HUMAN (386-586): 8.2e-16: 81.7: 23.47
+	Hs
		992873 POC1B_HUMAN (324-507): 1.91e-26: 114: 17.94		RACK1_HUMAN (386-586): 8.2e-16: 81.7: 23.47