Protein: THIOM
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)

Gene: THIOM, Txn2
Organism: Mus musculus
Interactions: 169
UniProt ID: P97493

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0006979 - response to oxidative stress
GO:0008113 - peptide-methionine (S)-S-oxide reductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

139705

PRDX6
Peroxiredoxin-6

1

20

High-throughput

0.575

High

139927

PRDX4
Peroxiredoxin-4

1

20

High-throughput

0.575

High

561158

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

4

High-throughput

0.575

High

589514

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

20

High-throughput

0.575

High

727682

PRDX1
Peroxiredoxin-1

1

20

High-throughput

0.575

High

956717

PRDX5
Peroxiredoxin-5, mitochondrial

1

6

High-throughput

0.575

High

956730

PRDX2
Peroxiredoxin-2

1

20

High-throughput

0.575

High

956783

MSRA
Mitochondrial peptide methionine sulfoxide reductase

1

4

High-throughput

0.575

High

193435

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

3

High-throughput

0.514

High

595804

TNNC2
Troponin C, skeletal muscle

1

1

High-throughput

0.514

High

933696

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.514

High

956728

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

4

High-throughput

0.514

High

956740

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.514

High

956743

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

6

High-throughput

0.514

High

956754

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

2

High-throughput

0.514

High

956772

PLST
Plastin-3

1

4

High-throughput

0.514

High

956780

ERP44
Endoplasmic reticulum resident protein 44

1

16

High-throughput

0.514

High

956798

MLRA
Myosin regulatory light chain 2, atrial isoform

1

3

High-throughput

0.514

High

956805

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

3

High-throughput

0.514

High

139111

DPYL2
Dihydropyrimidinase-related protein 2

1

2

High-throughput

0.445

High

140350

SODE
Extracellular superoxide dismutase [Cu-Zn]

1

10

High-throughput

0.445

High

223113

SEPT7
Septin-7

1

2

High-throughput

0.445

High

292366

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

1

High-throughput

0.445

High

355175

HBB1
Hemoglobin subunit beta-1

1

4

High-throughput

0.445

High

355186

HBB2
Hemoglobin subunit beta-2

1

4

High-throughput

0.445

High

410697

LDHA
L-lactate dehydrogenase A chain

1

7

High-throughput

0.445

High

514319

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.445

High

536044

RSSA
Small ribosomal subunit protein uS2

1

4

High-throughput

0.445

High

537694

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.445

High

560433

ASSY
Argininosuccinate synthase

1

1

High-throughput

0.445

High

562129

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

8

High-throughput

0.445

High

566047

ENOA
Alpha-enolase

1

6

High-throughput

0.445

High

578584

COF1
Cofilin-1

1

2

High-throughput

0.445

High

599322

ENOB
Beta-enolase

1

6

High-throughput

0.445

High

621298

CRYAB
Alpha-crystallin B chain

1

1

High-throughput

0.445

High

623424

AL1A1
Aldehyde dehydrogenase 1A1

1

4

High-throughput

0.445

High

751912

GRP75
Stress-70 protein, mitochondrial

1

13

High-throughput

0.445

High

812894

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

4

High-throughput

0.445

High

840022

VATA
V-type proton ATPase catalytic subunit A

1

5

High-throughput

0.445

High

880612

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.445

High

885075

ACTN4
Alpha-actinin-4

1

2

High-throughput

0.445

High

886065

TB182
182 kDa tankyrase-1-binding protein

1

1

High-throughput

0.445

High

919324

RAN
GTP-binding nuclear protein Ran

1

3

High-throughput

0.445

High

926302

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.445

High

930591

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.445

High

932484

ACTC
Actin, alpha cardiac muscle 1

1

8

High-throughput

0.445

High

936749

IDHG1
Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial

1

3

High-throughput

0.445

High

936798

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

6

High-throughput

0.445

High

956719

ATPA
ATP synthase subunit alpha, mitochondrial

1

4

High-throughput

0.445

High

956733

DPYL3
Dihydropyrimidinase-related protein 3

1

2

High-throughput

0.445

High

956737

KCRS
Creatine kinase S-type, mitochondrial

1

2

High-throughput

0.445

High

956738

SYNE2
Nesprin-2

1

2

High-throughput

0.445

High

956741

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

956742

EFTU
Elongation factor Tu, mitochondrial

1

4

High-throughput

0.445

High

956746

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.445

High

956748

FLNA
Filamin-A

1

9

High-throughput

0.445

High

956751

MIC60
MICOS complex subunit Mic60

1

2

High-throughput

0.445

High

956752

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

6

High-throughput

0.445

High

956755

AL1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase

1

4

High-throughput

0.445

High

956756

Q8R112
Ttn protein

1

6

High-throughput

0.445

High

956757

ERO1A
ERO1-like protein alpha

1

9

High-throughput

0.445

High

956760

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.445

High

956762

Q8VCQ8
Caldesmon 1

1

2

High-throughput

0.445

High

956765

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

2

High-throughput

0.445

High

956766

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

1

High-throughput

0.445

High

956767

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

1

High-throughput

0.445

High

956769

TWF1
Twinfilin-1

1

2

High-throughput

0.445

High

956773

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.445

High

956774

PARK7
Parkinson disease protein 7 homolog

1

4

High-throughput

0.445

High

956775

ACS2L
Acetyl-coenzyme A synthetase 2-like, mitochondrial

1

2

High-throughput

0.445

High

956778

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

3

High-throughput

0.445

High

956782

IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

3

High-throughput

0.445

High

956786

CNN3
Calponin-3

1

5

High-throughput

0.445

High

956788

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.445

High

956790

ECHP
Peroxisomal bifunctional enzyme

1

2

High-throughput

0.445

High

956797

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

1

6

High-throughput

0.445

High

956802

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.445

High

618934

IRF8
Interferon regulatory factor 8

1

1

High-throughput

0.437

High

222654

AKAP2
PALM2-AKAP2 fusion protein

1

0

High-throughput

0.426

High

516264

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.426

High

532719

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

1

0

High-throughput

0.426

High

554794

CAH3
Carbonic anhydrase 3

1

0

High-throughput

0.426

High

910230

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.426

High

915140

RS4X
Small ribosomal subunit protein eS4

1

0

High-throughput

0.426

High

956722

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.426

High

956731

IGBP1
Immunoglobulin-binding protein 1

1

0

High-throughput

0.426

High

956735

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.426

High

956770

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.426

High

956771

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.426

High

956777

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.426

High

956781

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.426

High

956791

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.426

High

956792

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.426

High

69788

B1AQ77
Keratin 15

1

3

High-throughput

0.407

High

192429

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

2

High-throughput

0.407

High

393846

ALDOA
Fructose-bisphosphate aldolase A

1

5

High-throughput

0.407

High

409483

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

1

High-throughput

0.407

High

426895

KCRM
Creatine kinase M-type

1

2

High-throughput

0.407

High

427718

ANXA2
Annexin A2

1

5

High-throughput

0.407

High

525128

GELS
Gelsolin

1

1

High-throughput

0.407

High

554839

LEG1
Galectin-1

1

9

High-throughput

0.407

High

568430

SBP1
Methanethiol oxidase

1

1

High-throughput

0.407

High

570798

TPIS
Triosephosphate isomerase

1

3

High-throughput

0.407

High

589624

VIME
Vimentin

1

5

High-throughput

0.407

High

640173

TLN1
Talin-1

1

1

High-throughput

0.407

High

660830

MEP1A
Meprin A subunit alpha

1

5

High-throughput

0.407

High

786245

SEPT2
Septin-2

1

2

High-throughput

0.407

High

805501

MYO1B
Unconventional myosin-Ib

1

4

High-throughput

0.407

High

812920

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.407

High

812939

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.407

High

844340

ICAL
Calpastatin

1

2

High-throughput

0.407

High

880534

CDD
Cytidine deaminase

1

1

High-throughput

0.407

High

888803

PCBP1
Poly(rC)-binding protein 1

1

3

High-throughput

0.407

High

892162

ACTB
Actin, cytoplasmic 1

1

7

High-throughput

0.407

High

897160

ACTZ
Alpha-centractin

1

10

High-throughput

0.407

High

904240

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

4

High-throughput

0.407

High

910980

RS18
Small ribosomal subunit protein uS13

1

1

High-throughput

0.407

High

915549

ACTA
Actin, aortic smooth muscle

1

8

High-throughput

0.407

High

918836

VATB2
V-type proton ATPase subunit B, brain isoform

1

5

High-throughput

0.407

High

933082

ACTS
Actin, alpha skeletal muscle

1

8

High-throughput

0.407

High

936744

MYBPH
Myosin-binding protein H

1

6

High-throughput

0.407

High

956502

MYL11
Myosin regulatory light chain 11

1

3

High-throughput

0.407

High

956718

RSU1
Ras suppressor protein 1

1

1

High-throughput

0.407

High

956720

CNN2
Calponin-2

1

5

High-throughput

0.407

High

956725

Q5M8R7
Ldhb protein

1

2

High-throughput

0.407

High

956726

MYPC2
Myosin-binding protein C, fast-type

1

8

High-throughput

0.407

High

956727

SRC8
Src substrate cortactin

1

5

High-throughput

0.407

High

956729

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.407

High

956732

LASP1
LIM and SH3 domain protein 1

1

5

High-throughput

0.407

High

956734

MYOM1
Myomesin-1

1

2

High-throughput

0.407

High

956736

SBP2
Selenium-binding protein 2

1

1

High-throughput

0.407

High

956745

DUS29
Dual specificity phosphatase 29

1

5

High-throughput

0.407

High

956747

Q8BRB8
PDZ domain-containing protein

1

2

High-throughput

0.407

High

956749

SEP11
Septin-11

1

2

High-throughput

0.407

High

956753

CBR3
Carbonyl reductase [NADPH] 3

1

2

High-throughput

0.407

High

956759

ACY2
Aspartoacylase

1

1

High-throughput

0.407

High

956761

TXLNB
Beta-taxilin

1

3

High-throughput

0.407

High

956763

MYH9
Myosin-9

1

1

High-throughput

0.407

High

956764

VIGLN
Vigilin

1

6

High-throughput

0.407

High

956768

ACY3
N-acyl-aromatic-L-amino acid amidohydrolase

1

1

High-throughput

0.407

High

956779

ILEUA
Leukocyte elastase inhibitor A

1

2

High-throughput

0.407

High

956784

DUS3
Dual specificity protein phosphatase 3

1

5

High-throughput

0.407

High

956785

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.407

High

956793

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

6

High-throughput

0.407

High

956794

Q9JHR4
Myosin heavy chain IIB

1

2

High-throughput

0.407

High

956795

Q9JHV3
Klra19 protein

1

3

High-throughput

0.407

High

956796

MYOTI
Myotilin

1

6

High-throughput

0.407

High

956799

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

9

High-throughput

0.407

High

956800

DEST
Destrin

1

2

High-throughput

0.407

High

956803

RUVB2
RuvB-like 2

1

1

High-throughput

0.407

High

956804

CCS
Copper chaperone for superoxide dismutase

1

10

High-throughput

0.407

High

90159

D6RJ85
RNA binding motif protein 39

1

0

High-throughput

0.232

Low

93710

E9Q851
Rac GTPase-activating protein 1

1

0

High-throughput

0.232

Low

429986

ALBU
Albumin

1

0

High-throughput

0.232

Low

588467

LSP1
Lymphocyte-specific protein 1

1

0

High-throughput

0.232

Low

777820

INMT
Indolethylamine N-methyltransferase

1

0

High-throughput

0.232

Low

814216

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

High-throughput

0.232

Low

867159

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.232

Low

956721

UAP1L
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1

1

0

High-throughput

0.232

Low

956723

Q3UWR0
PWWP domain-containing protein

1

0

High-throughput

0.232

Low

956724

ST1D1
Sulfotransferase 1 family member D1

1

0

High-throughput

0.232

Low

956739

3HAO
3-hydroxyanthranilate 3,4-dioxygenase

1

0

High-throughput

0.232

Low

956744

Q8BIL4
Uncharacterized protein

1

0

High-throughput

0.232

Low

956750

CA198
Uncharacterized protein C1orf198 homolog

1

0

High-throughput

0.232

Low

956758

Q8R1X5
Edem3 protein

1

0

High-throughput

0.232

Low

956776

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.232

Low

956787

IAH1
Isoamyl acetate-hydrolyzing esterase 1 homolog

1

0

High-throughput

0.232

Low

956789

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

0

High-throughput

0.232

Low

956801

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024