HitPredict

Interactor 1: EP300 (B2RWS6)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: KAT2B (Q9JHD1)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.835

The method score is based on:

Property Details
Experiments 20211142, 9742083, 9659901
Identification Methods two hybrid, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bromodomain~Bromodomain, Bromodomain~RING_CBP-p300
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000123 - histone acetyltransferase complex
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
and 17 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2412
Mm

1 813
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024