Protein: WWP1
E3 ubiquitin-protein ligase wwp-1 (EC 2.3.2.26)

Gene: WWP1, wwp-1
Organism: Caenorhabditis elegans
Interactions: 53
UniProt ID: Q9N2Z7

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0008340 - determination of adult lifespan
GO:0016567 - protein ubiquitination
GO:0042176 - regulation of protein catabolic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1170314

UBC18
Ubiquitin-conjugating enzyme E2 ubc-18

3

20

Small-scale

0.867

High

1444897

Q9U2T9
Intersectin-1

1

6

High-throughput

0.656

High

1444902

Q9XXI4
Arrestin C-terminal-like domain-containing protein

2

20

High-throughput

0.640

High

111379

G5ED33
Epidermal growth factor receptor pathway substrate 8 splice variant A

2

9

High-throughput

0.632

High

810581

DYN1
Dynamin

2

1

High-throughput

0.632

High

758613

PAC1
GTPase-activating protein pac-1

2

7

High-throughput

0.594

High

1166369

Q18966
GRAM domain-containing protein

2

10

High-throughput

0.584

High

1166401

Q19016
C2 domain-containing protein

1

2

High-throughput

0.570

High

1376997

Q95PX7
WW domain-containing protein

1

20

High-throughput

0.570

High

1444892

KLF1
Kruppel-like factor 1

1

14

Small-scale

0.561

High

1171394

LGG2
Protein lgg-2

1

9

High-throughput

0.560

High

1285999

Q86MN9
WW domain-containing protein

1

1

High-throughput

0.555

High

1444903

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

15

High-throughput

0.541

High

145294

O01900
TFIIS central domain-containing protein

1

13

High-throughput

0.512

High

233475

O44760
HTH La-type RNA-binding domain-containing protein

1

9

High-throughput

0.512

High

264111

PHM2
Pharyngeal muscle protein 2

1

11

High-throughput

0.512

High

759268

CCNT2
Cyclin-T1.2

1

5

High-throughput

0.512

High

1170400

Q21746
SGTA homodimerisation domain-containing protein

1

16

High-throughput

0.512

High

1171053

Q22805
C3H1-type domain-containing protein

1

2

High-throughput

0.512

High

1191519

Q3Y407
Ground-like domain-containing protein

1

5

High-throughput

0.512

High

1286009

SYD1
Rho GTPase-activating protein syd-1

1

6

High-throughput

0.512

High

1373911

Q94184
LITAF domain-containing protein

1

8

High-throughput

0.512

High

1444893

Q9TZK8
J domain-containing protein

1

1

High-throughput

0.512

High

1444898

Q9U304
RRM domain-containing protein

1

8

High-throughput

0.512

High

1444901

Q9XWV4
RRM domain-containing protein

1

9

High-throughput

0.512

High

1083537

CCNB1
G2/mitotic-specific cyclin-B1

1

1

Small-scale

0.501

High

233412

O44606

1

3

High-throughput

0.494

High

233998

NH111
Nuclear hormone receptor family member nhr-111

1

17

High-throughput

0.494

High

1166409

Q19019
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.494

High

1230708

Q6ABG8
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.481

High

1444891

Q9N3F4
RNA helicase

1

12

High-throughput

0.481

High

1165870

IFY1
Securin-like protein

1

0

Small-scale

0.480

High

111941

VAB3
Paired box protein 6 homolog

1

3

High-throughput

0.457

High

1226070

Q65XX1
RNA helicase

1

12

High-throughput

0.457

High

1378725

Q95XY1
RNA helicase

1

13

High-throughput

0.457

High

113700

G5EG65
HID-1

1

1

High-throughput

0.451

High

115539

H2KZI6
C3H1-type domain-containing protein

1

1

High-throughput

0.451

High

1444895

Q9U252
Arginine/serine-rich protein PNISR

1

6

High-throughput

0.451

High

1444899

Q9U3E2
LIM interaction domain-containing protein

1

6

High-throughput

0.451

High

72245

A8XQ35
Arginine/serine-rich protein PNISR

1

1

High-throughput

0.439

High

112578

LIDB1
LIM domain-binding protein 1

1

1

High-throughput

0.439

High

145720

O02174
C3H1-type domain-containing protein

1

1

High-throughput

0.439

High

1275281

Q7Z135
Protein HID1

1

1

High-throughput

0.439

High

1306843

Q8ITW3
BZIP domain-containing protein

1

1

High-throughput

0.439

High

116024

H2L0F6
BZIP domain-containing protein

1

1

High-throughput

0.417

High

1018937

P91245
Membrane protein BRI3

1

0

High-throughput

0.292

High

1165122

YTE4
Uncharacterized protein C09G1.4

1

0

High-throughput

0.292

High

1169824

Q20631
Early nodulin-75-like

1

0

High-throughput

0.292

High

1444896

Q9U2N7
Deoxyribonuclease TATDN2

1

0

High-throughput

0.292

High

1444900

YS0I
Uncharacterized protein F08G2.4

1

0

High-throughput

0.292

High

1169594

Q20048
Malonyl-CoA decarboxylase, mitochondrial

1

0

High-throughput

0.282

High

1427954

Q9GYJ3
ShKT domain-containing protein

1

0

High-throughput

0.282

High

1444894

Q9TZL2
GED domain-containing protein

1

0

High-throughput

0.257

Low


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Last updated: 11Aug2025