HitPredict

Interactor 1: UBC18 (Q21633)
Ubiquitin-conjugating enzyme E2 ubc-18 (EC 2.3.2.23)
Gene: ubc-18

Interactor 2: WWP1 (Q9N2Z7)
E3 ubiquitin-protein ligase wwp-1 (EC 2.3.2.26)
Gene: wwp-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 16457801, 19123269, 19553937
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HECT~UQ_con
Common GO terms GO:0008340 - determination of adult lifespan
GO:0016567 - protein ubiquitination
GO:0061631 - ubiquitin conjugating enzyme activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 153
Ce

1 794
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Service provided by Combinatics, Japan

Last updated: 11Aug2025