Protein: G5ED33
Epidermal growth factor receptor pathway substrate 8 splice variant A (SH3 domain-containing protein)

Gene: G5ED33, eps-8
Organism: Caenorhabditis elegans
Interactions: 59
UniProt ID: G5ED33

Gene Ontology (top 5):
GO:0002119 - nematode larval development
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005903 - brush border

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

111354

LIN2
Protein lin-2

4

11

Small-scale

0.875

High

111347

ABL1
Tyrosine-protein kinase abl-1

2

20

High-throughput

0.801

High

111382

Q9U2T9
Intersectin-1

2

20

Small-scale

0.768

High

110344

SRBS1
Sorbin and SH3 domain-containing protein 1 homolog

2

20

High-throughput

0.754

High

111335

G5ED33
Epidermal growth factor receptor pathway substrate 8 splice variant A

1

18

High-throughput

0.656

High

111337

SRC1
Tyrosine protein-kinase src-1

1

20

High-throughput

0.656

High

111345

SRC2
Tyrosine protein-kinase src-2

1

20

High-throughput

0.656

High

111350

LASP1
LIM and SH3 domain protein F42H10.3

1

20

High-throughput

0.656

High

111356

Q10929
SH3 domain-containing protein

1

20

High-throughput

0.656

High

111361

PEX13
Peroxisomal membrane protein PEX13

1

20

High-throughput

0.656

High

111383

Q9U2Z5
Osteoclast-stimulating factor 1

1

15

High-throughput

0.656

High

111379

WWP1
E3 ubiquitin-protein ligase wwp-1

2

9

High-throughput

0.632

High

110409

G5EC35
Beta chain spectrin homolog Sma1

1

17

High-throughput

0.621

High

111360

Q18239
DiSHevelled related

1

20

High-throughput

0.621

High

109655

G5EBH3
Spectrin beta chain

1

17

High-throughput

0.590

High

111368

MIG5
Segment polarity protein dishevelled homolog mig-5

1

20

High-throughput

0.590

High

111342

O02174
C3H1-type domain-containing protein

3

2

High-throughput

0.589

High

111338

G5EFG1
PDZ and LIM domain protein Zasp

2

19

High-throughput

0.584

High

111352

LIN36
Protein lin-36

3

6

High-throughput

0.583

High

111341

UNC89
Muscle M-line assembly protein unc-89

1

6

Small-scale

0.555

High

111359

YTE4
Uncharacterized protein C09G1.4

1

1

High-throughput

0.512

High

110785

TACC1
Transforming acid coiled-coil-containing protein 1

1

0

High-throughput

0.486

High

111336

G5EDN8
ANK_REP_REGION domain-containing protein

1

12

Small-scale

0.481

High

111376

PAT12
Protein pat-12

1

1

High-throughput

0.481

High

111349

PLK1
Serine/threonine-protein kinase plk-1

1

2

High-throughput

0.479

High

111343

O16638
EF-hand domain-containing protein

1

2

High-throughput

0.464

High

111346

PHM2
Pharyngeal muscle protein 2

1

15

High-throughput

0.464

High

111362

Q20476
BTB domain-containing protein

1

12

High-throughput

0.464

High

111369

Q22387
Centrosomal protein of 162 kDa

1

3

High-throughput

0.464

High

111374

Q8MQ13
Potassium channel tetramerisation-type BTB domain-containing protein

1

15

High-throughput

0.464

High

111375

HM08
Homeobox protein ceh-8

1

6

High-throughput

0.464

High

110646

G5EC72
PDZ and LIM domain protein Zasp

1

20

High-throughput

0.457

High

111339

H2KZI6
C3H1-type domain-containing protein

1

2

High-throughput

0.451

High

111358

Q17744
EF-hand domain-containing protein

1

2

High-throughput

0.451

High

111340

H8W3X6
EF-hand domain-containing protein

1

2

High-throughput

0.439

High

111348

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

2

High-throughput

0.439

High

111351

ESS2
Splicing factor ESS-2

1

1

High-throughput

0.439

High

111355

GEX3
Membrane-associated protein gex-3

1

3

Small-scale

0.439

High

111372

Q8IU04
RING-type domain-containing protein

1

1

High-throughput

0.439

High

111377

Q95QI3
PDZ domain-containing protein

1

4

High-throughput

0.439

High

111378

Q9GYK4
Charged multivesicular body protein 3

1

8

High-throughput

0.439

High

111386

F161
Protein fam-161

1

2

High-throughput

0.439

High

111344

O44490
ELKS/RAB6-interacting/CAST family member 2

1

11

High-throughput

0.437

High

49373

A0PD34
BTB domain-containing protein

1

15

High-throughput

0.417

High

111370

Q4VNJ8
LIN-65S

1

1

High-throughput

0.417

High

111373

Q8MNT0
PDZ domain-containing protein

1

4

High-throughput

0.417

High

111353

ZTF17
Zinc finger transcription factor family protein 17

2

0

High-throughput

0.329

High

111367

HIUH1
Probable 5-hydroxyisourate hydrolase R09H10.3

2

0

High-throughput

0.329

High

111357

YPC4
Uncharacterized protein C05D10.4

1

0

High-throughput

0.265

Low

111363

Q20712
CLASP_N domain-containing protein

1

0

High-throughput

0.265

Low

111364

Q20759
GDP/GTP exchange factor Sec2 N-terminal domain-containing protein

1

0

High-throughput

0.265

Low

111365

Q20769
NIM-2 protein

1

0

High-throughput

0.265

Low

111366

Q21648

1

0

High-throughput

0.265

Low

111380

SCPL3
CTD small phosphatase-like protein 3

1

0

High-throughput

0.265

Low

111381

Q9NET8
Verprolin

1

0

High-throughput

0.265

Low

111384

Q9XTW8
Glycine-rich cell wall structural protein 1

1

0

High-throughput

0.265

Low

111385

Q9XUW7
GATA-type domain-containing protein

1

0

High-throughput

0.265

Low

111371

Q8ITW3
BZIP domain-containing protein

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025