Protein: MEL26
Protein maternal effect lethal 26

Gene: MEL26, mel-26
Organism: Caenorhabditis elegans
Interactions: 74
UniProt ID: Q94420

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0000209 - protein polyubiquitination
GO:0000793 - condensed chromosome
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1374040

MEL26
Protein maternal effect lethal 26

7

14

Small-scale

0.964

High

1164811

CUL3
Cullin-3

6

20

Small-scale

0.963

High

760741

KTNA1
Meiotic spindle formation protein mei-1

10

4

Small-scale

0.758

High

939152

SUMO
Small ubiquitin-related modifier

5

2

Small-scale

0.721

High

1164953

Q17581
Bromo domain-containing protein

2

7

Small-scale

0.632

High

1165917

Q18241
Helicase ARIP4

2

3

Small-scale

0.632

High

1374042

YKKA
Putative zinc finger protein C02F5.12

3

0

Small-scale

0.625

High

1170530

MED15
Mediator of RNA polymerase II transcription subunit 15

2

0

Small-scale

0.605

High

1374055

HECD1
E3 ubiquitin-protein ligase hecd-1

1

6

Small-scale

0.590

High

1169742

RAB33
Ras-related protein Rab-33

2

2

Small-scale

0.584

High

1374053

Q9XW53
Rho GTPase-activating protein 20

2

3

Small-scale

0.584

High

1067092

PCF11
Polyadenylation and cleavage factor homolog 11

2

1

High-throughput

0.576

High

114771

H1ZUX3
RING-type domain-containing protein

2

0

High-throughput

0.561

High

303825

O76398
C2H2-type domain-containing protein

1

5

High-throughput

0.560

High

111957

G5EDS2
Coronin-7

1

5

Small-scale

0.552

High

195329

FIGL1
Fidgetin-like protein 1

1

5

Small-scale

0.552

High

145095

UNC89
Muscle M-line assembly protein unc-89

1

3

Small-scale

0.549

High

110850

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

0

Small-scale

0.543

High

1171183

UNC83
Nuclear migration protein unc-83

2

1

Small-scale

0.543

High

110336

HCF1
Host cell factor homolog hcf-1

1

19

Small-scale

0.541

High

114044

CATZ1
Cathepsin Z-1

1

1

High-throughput

0.541

High

196389

SET6
Histone-lysine N-methyltransferase set-6

1

3

Small-scale

0.541

High

263890

O61845
Chromodomain and Helicase Domain protein

1

4

Small-scale

0.541

High

758643

YKR1
KH domain-containing protein hrpk-2

1

8

Small-scale

0.541

High

760702

PAL1
Homeobox protein pal-1

1

8

High-throughput

0.541

High

1166596

SCC1
Sister chromatid cohesion protein 1

1

1

Small-scale

0.541

High

1374041

UBC9
SUMO-conjugating enzyme UBC9

1

15

Small-scale

0.541

High

1374044

NHR97
Nuclear hormone receptor family member nhr-97

1

10

Small-scale

0.541

High

234216

NUD2
Protein nud-2

1

0

High-throughput

0.536

High

1066937

LAG3
Protein lag-3

1

0

High-throughput

0.536

High

1171007

TM201
Transmembrane protein 201 homolog

1

0

High-throughput

0.536

High

1372635

NEDD8
Ubiquitin-like protein NEDD8

1

7

Small-scale

0.536

High

115303

H2KYX3
FERM domain-containing protein

1

10

High-throughput

0.518

High

233737

O45146
Embryonic mRna

1

0

Small-scale

0.518

High

1170663

ATF4H
Transcription factor atf-4 homolog

1

0

Small-scale

0.518

High

1374049

Q9TYQ2
RNase NYN domain-containing protein

1

0

Small-scale

0.518

High

1374054

Q9XWB4
Major sperm protein

1

0

Small-scale

0.518

High

1164895

Q17493
Maelstrom domain-containing protein

1

3

High-throughput

0.512

High

1171352

RBX1
RING-box protein 1

1

8

Small-scale

0.501

High

109641

G5EBG1
Vitelline membrane outer layer protein 1

1

3

Small-scale

0.494

High

113808

G5EGE8
S phase cyclin A-associated protein in the endoplasmic reticulum N-terminal domain-containing protein

1

12

Small-scale

0.494

High

1171191

Q23083
Phosphatidylinositol 4-kinase type 2

1

1

Small-scale

0.494

High

1171350

Q23456
BPTI/Kunitz inhibitor domain-containing protein

1

3

Small-scale

0.494

High

1374051

Q9XUT0
DreBriN 1/DreBriN-like

1

5

Small-scale

0.494

High

115381

H2KZ17
DiSHevelled related

1

15

High-throughput

0.481

High

115420

H2KZ39
Forkhead box protein pes-1

1

5

Small-scale

0.481

High

233453

MEI2
Meiotic spindle formation protein 2

1

0

Small-scale

0.458

High

73243

B1Q240
DiSHevelled related

1

15

High-throughput

0.457

High

115729

ZTF16
Zinc finger protein ztf-16

1

3

Small-scale

0.457

High

115476

H2KZD6
HAT C-terminal dimerisation domain-containing protein

1

1

High-throughput

0.451

High

116098

ARL13
ADP-ribosylation factor-like protein 13B

1

5

Small-scale

0.439

High

144746

O01526
HAT C-terminal dimerisation domain-containing protein

1

1

High-throughput

0.439

High

857663

GOP1
Protein CLEC16A homolog

1

2

Small-scale

0.439

High

1374043

Q967F3
SH2 domain-containing protein

1

2

Small-scale

0.439

High

115821

H2L091
SH2 domain-containing protein

1

3

Small-scale

0.417

High

1374048

Q9NF71
ELM2 domain-containing protein

3

0

Small-scale

0.355

High

1374045

Q9GYQ9
CCR4-NOT transcription complex subunit 4

2

0

Small-scale

0.335

High

1066886

YQ15
Uncharacterized protein C05C10.5

2

0

Small-scale

0.334

High

1170334

Q21648

2

0

High-throughput

0.334

High

1165626

Q18013
GRIP domain-containing protein

2

0

Small-scale

0.329

High

1167038

Q19994
C2H2-type domain-containing protein

1

0

High-throughput

0.292

High

1372564

Q93510
Cactin_mid domain-containing protein

1

0

High-throughput

0.292

High

113474

G5EFM8
PAP-associated domain-containing protein

1

0

High-throughput

0.282

High

145464

O02076
FAM192A_Fyv6_N domain-containing protein

1

0

High-throughput

0.282

High

196796

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.282

High

264055

O62124
ERCC4 domain-containing protein

1

0

Small-scale

0.282

High

1018895

P91051
SKA2 domain-containing protein

1

0

High-throughput

0.282

High

1170287

Q21541
AD domain-containing protein

1

0

Small-scale

0.282

High

1372565

Q93520
AAA domain-containing protein

1

0

High-throughput

0.282

High

1374046

Q9N3I5
Lzipper-MIP1 domain-containing protein

1

0

High-throughput

0.282

High

1374047

Q9N5L0
tRNA

1

0

Small-scale

0.282

High

1374052

UNC80
Protein unc-80

1

0

Small-scale

0.282

High

1374050

Q9TZI2
RRM domain-containing protein

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025