Protein: SUMO
Small ubiquitin-related modifier (SUMO) (Ubiquitin-like protein SMT3)

Gene: SUMO, smo-1
Organism: Caenorhabditis elegans
Interactions: 70
UniProt ID: P55853

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002119 - nematode larval development
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

939151

GEI17
E3 SUMO-protein ligase gei-17

5

20

Small-scale

0.920

High

939153

UBC9
SUMO-conjugating enzyme UBC9

5

19

Small-scale

0.918

High

939124

SUMO
Small ubiquitin-related modifier

4

12

Small-scale

0.888

High

939152

MEL26
Protein maternal effect lethal 26

5

2

Small-scale

0.721

High

195319

FIGL1
Fidgetin-like protein 1

3

11

Small-scale

0.674

High

939127

ULP4
Ubiquitin-like protease 4

1

20

Small-scale

0.647

High

939128

SENP
Sentrin-specific protease

1

20

Small-scale

0.647

High

939125

FAN1
Fanconi-associated nuclease 1 homolog

2

0

High-throughput

0.613

High

116186

H2L2C8
Alpha-actinin, sarcomeric

3

8

High-throughput

0.583

High

939129

PAR3
Partitioning defective protein 3

2

1

High-throughput

0.576

High

939141

BARD1
BRCA1-associated RING domain protein 1

2

1

Small-scale

0.576

High

939142

MEP1
MOG interacting and ectopic P-granules protein 1

2

1

High-throughput

0.576

High

939145

TPM1
Tropomyosin isoforms a/b/d/f

2

1

High-throughput

0.576

High

939165

MBK2
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2

2

8

High-throughput

0.576

High

939154

SOP2
Polycomb protein sop-2

1

3

Small-scale

0.561

High

116048

H2L0F9
Exonuclease domain-containing protein

2

0

High-throughput

0.551

High

264030

PRY1
Axin-like protein pry-1

2

0

High-throughput

0.551

High

939146

Q23158
Alpha-actinin, sarcomeric

2

8

High-throughput

0.544

High

939144

DYL1
Dynein light chain 1, cytoplasmic

1

1

High-throughput

0.541

High

628553

LIN11
Protein lin-11

1

0

Small-scale

0.537

High

939139

ADD2
Adducin-related protein 2

1

0

High-throughput

0.536

High

939157

Q9GZG5
ERCC4 domain-containing protein

1

0

High-throughput

0.536

High

939162

Q9NF71
ELM2 domain-containing protein

1

0

High-throughput

0.536

High

939149

DVE1
Homeobox protein dve-1

1

0

Small-scale

0.529

High

939156

Q9GYG1
C2H2-type domain-containing protein

1

0

Small-scale

0.529

High

113469

G5EFM8
PAP-associated domain-containing protein

2

1

High-throughput

0.526

High

939131

Q18076
G domain-containing protein

2

1

High-throughput

0.526

High

939137

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.518

High

939159

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.518

High

939134

Q18994
Translation initiation factor eIF2B subunit epsilon

1

1

High-throughput

0.512

High

810568

DYN1
Dynamin

1

3

High-throughput

0.508

High

111791

G5EDL0
ETS domain-containing protein

1

3

Small-scale

0.501

High

113528

HSF1
Heat shock transcription factor hsf-1

1

4

Small-scale

0.501

High

144602

AIR2
Aurora/IPL1-related protein kinase 2

1

3

Small-scale

0.501

High

878242

DPY27
Chromosome condensation protein dpy-27

1

7

Small-scale

0.501

High

939132

Q18241
Helicase ARIP4

1

16

Small-scale

0.501

High

939143

BUB1
Mitotic checkpoint serine/threonine-protein kinase bub-1

1

6

Small-scale

0.501

High

939164

CND1
Condensin complex subunit 1

1

2

Small-scale

0.501

High

63417

A5JYT9
C2H2-type domain-containing protein

1

2

High-throughput

0.494

High

113019

G5EF87
SWI/SNF complex subunit SMARCC2

1

5

High-throughput

0.494

High

116571

H8ESF3
SWI/SNF complex subunit SMARCC2

1

3

High-throughput

0.481

High

939135

NHR25
Nuclear hormone receptor family member nhr-25

1

16

Small-scale

0.481

High

939138

Q20130
C2H2-type domain-containing protein

1

3

High-throughput

0.481

High

939148

Q86G90
Nuclear Pore complex Protein

1

9

High-throughput

0.481

High

939150

Q86NC1
Alpha-1,4 glucan phosphorylase

1

1

High-throughput

0.481

High

939155

HMR1
Cadherin-related hmr-1

1

0

Small-scale

0.480

High

232030

HMP2
Beta-catenin-like protein hmp-2

1

3

Small-scale

0.479

High

939126

SPD5
Spindle-defective protein 5

1

1

High-throughput

0.479

High

939163

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.458

High

939168

LS14H
Protein LSM14 homolog car-1

1

0

Small-scale

0.458

High

110125

EGL9
Hypoxia-inducible factor prolyl hydroxylase

1

3

High-throughput

0.457

High

939140

Q21021
Nuclear Pore complex Protein

1

9

High-throughput

0.457

High

939160

Q9N5U1
Alpha-1,4 glucan phosphorylase

1

1

High-throughput

0.457

High

113497

G5EFR3
PAP-associated domain-containing protein

1

1

High-throughput

0.451

High

115098

H2KYD4
C2H2-type domain-containing protein

1

3

High-throughput

0.451

High

63080

A5A8Q6
C2H2-type domain-containing protein

1

2

High-throughput

0.439

High

939147

Q2AAC3
Glutaredoxin domain-containing protein

1

1

High-throughput

0.439

High

234403

RL18
Large ribosomal subunit protein eL18

1

2

Small-scale

0.437

High

939136

RL26
Large ribosomal subunit protein uL24

1

2

Small-scale

0.437

High

939166

RL8
Large ribosomal subunit protein uL2

1

1

Small-scale

0.437

High

115272

H2KYV3
G domain-containing protein

1

1

High-throughput

0.417

High

939158

Q9N4P2
Glutaredoxin domain-containing protein

1

1

High-throughput

0.417

High

939167

Q9XVU8
Alpha-actinin, sarcomeric

1

7

High-throughput

0.417

High

234067

O45548
Phosphoprotein

1

0

High-throughput

0.292

High

939130

Q17987
Fibrous sheath-interacting protein 1

1

0

High-throughput

0.292

High

939161

Q9NA84
SPK domain-containing protein

1

0

High-throughput

0.292

High

759450

MTSS1
Single-stranded DNA-binding protein, mitochondrial

1

0

Small-scale

0.249

Low

939133

Q18577
SXP/RAL-2 family protein Ani s 5-like cation-binding domain-containing protein

1

0

Small-scale

0.249

Low

115422

HRDE4
Protein hrde-4

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025