Protein: EIF3K
Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28)

Gene: EIF3K
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q9UBQ5

Gene Ontology (top 5):
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1354227

EIF3L
Eukaryotic translation initiation factor 3 subunit L

12

2

Small-scale

0.984

High

888454

EIF3E
Eukaryotic translation initiation factor 3 subunit E

7

1

Small-scale

0.964

High

1184160

EIF3M
Eukaryotic translation initiation factor 3 subunit M

7

1

Small-scale

0.964

High

124953

EIF3F
Eukaryotic translation initiation factor 3 subunit F

6

4

Small-scale

0.944

High

1049669

EIF3A
Eukaryotic translation initiation factor 3 subunit A

5

2

Small-scale

0.919

High

1305028

EIF3C
Eukaryotic translation initiation factor 3 subunit C

4

1

Small-scale

0.893

High

177101

EIF3H
Eukaryotic translation initiation factor 3 subunit H

7

5

Small-scale

0.746

High

879355

EIF3B
Eukaryotic translation initiation factor 3 subunit B

4

1

Small-scale

0.697

High

275948

EIF3G
Eukaryotic translation initiation factor 3 subunit G

4

1

Small-scale

0.696

High

1032167

EIF3I
Eukaryotic translation initiation factor 3 subunit I

5

0

High-throughput

0.688

High

176873

EIF3D
Eukaryotic translation initiation factor 3 subunit D

4

0

Small-scale

0.660

High

122097

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

High-throughput

0.656

High

1051928

IF4A2
Eukaryotic initiation factor 4A-II

3

1

High-throughput

0.650

High

276058

EIF3J
Eukaryotic translation initiation factor 3 subunit J

3

0

Small-scale

0.636

High

320049

HERC2
E3 ubiquitin-protein ligase HERC2

3

1

Small-scale

0.633

High

1272667

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.618

High

673173

CCND3
G1/S-specific cyclin-D3

2

0

Small-scale

0.614

High

934536

CSK21
Casein kinase II subunit alpha

2

2

High-throughput

0.611

High

890488

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.585

High

980013

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

2

2

Small-scale

0.584

High

529847

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.576

High

370624

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

780254

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

669041

PML
Protein PML

1

0

Small-scale

0.549

High

592552

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

213911

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

1

High-throughput

0.536

High

727076

FUS
RNA-binding protein FUS

1

1

High-throughput

0.536

High

780797

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

1

High-throughput

0.536

High

1054643

RBM39
RNA-binding protein 39

1

1

High-throughput

0.536

High

1120025

PDCD4
Programmed cell death protein 4

1

2

High-throughput

0.536

High

1312084

RBM42
RNA-binding protein 42

1

1

High-throughput

0.536

High

1344148

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.536

High

1354225

G3BP2
Ras GTPase-activating protein-binding protein 2

1

3

High-throughput

0.536

High

1354229

DRG1
Developmentally-regulated GTP-binding protein 1

1

1

High-throughput

0.536

High

134235

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.513

High

255207

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

283618

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

380342

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

High-throughput

0.513

High

403359

LA
Lupus La protein

1

0

High-throughput

0.513

High

417036

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

418749

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

448009

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

452908

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

508756

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

545914

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

0

High-throughput

0.513

High

643413

HMGB2
High mobility group protein B2

1

0

High-throughput

0.513

High

718273

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.513

High

736785

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

806208

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

813811

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

817764

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.513

High

828925

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

831069

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.513

High

841025

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

873883

IF5
Eukaryotic translation initiation factor 5

1

0

High-throughput

0.513

High

908196

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

923264

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

929706

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

1054009

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

1062408

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

1148388

RHG17
Rho GTPase-activating protein 17

1

0

High-throughput

0.513

High

1221903

DDX60
Probable ATP-dependent RNA helicase DDX60

1

0

High-throughput

0.513

High

1243433

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

1245218

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.513

High

1263573

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

1271778

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1304432

DNJC2
DnaJ homolog subfamily C member 2

1

0

High-throughput

0.513

High

1329252

TARA
TRIO and F-actin-binding protein

1

0

High-throughput

0.513

High

1349630

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

1354223

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

1354228

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

1354233

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

239624

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.493

High

158050

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

203417

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

1

2

High-throughput

0.479

High

228958

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

295353

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

295833

ST17B
Serine/threonine-protein kinase 17B

1

2

High-throughput

0.479

High

400123

ICAM1
Intercellular adhesion molecule 1

1

1

High-throughput

0.479

High

587041

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.479

High

640652

DDX6
Probable ATP-dependent RNA helicase DDX6

1

1

High-throughput

0.479

High

1030531

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

1038232

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

1

High-throughput

0.479

High

1038248

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

1

1

High-throughput

0.479

High

1243565

CSK23
Casein kinase II subunit alpha 3

1

2

High-throughput

0.479

High

1269833

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1354220

ST17A
Serine/threonine-protein kinase 17A

1

2

High-throughput

0.479

High

1354224

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1354234

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

125772

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

160828

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

298855

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

303521

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

316511

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.458

High

339079

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

414096

GELS
Gelsolin

1

0

High-throughput

0.458

High

530763

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

553960

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

570143

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

618727

IF4B
Eukaryotic translation initiation factor 4B

1

0

Small-scale

0.458

High

631616

BRD2
Bromodomain-containing protein 2

1

0

High-throughput

0.458

High

632435

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

652501

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

772192

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

875391

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

881052

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

887510

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.458

High

887976

CD81
CD81 antigen

1

0

High-throughput

0.458

High

896248

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

909270

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1022229

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1028033

ERCC8
DNA excision repair protein ERCC-8

1

0

Small-scale

0.458

High

1042741

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1064798

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1080437

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1086011

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1088250

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

0

High-throughput

0.458

High

1148842

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1159318

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1199707

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

1261438

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

1267216

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1281795

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.458

High

1286731

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

1303014

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1319101

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1343358

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1344406

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1354221

TRM7
tRNA

1

0

High-throughput

0.458

High

1354222

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1354226

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.458

High

1354231

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

1354232

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.458

High

72126

B3KS98
Eukaryotic translation initiation factor 3 subunit H

1

5

High-throughput

0.445

High

484216

CALM3
Calmodulin-3

1

1

High-throughput

0.445

High

828044

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.438

High

1081430

E2F4
Transcription factor E2F4

1

1

High-throughput

0.437

High

1331528

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

375032

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.426

High

497726

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

532636

TCTP
Translationally-controlled tumor protein

1

0

Small-scale

0.426

High

989162

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.426

High

1124644

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.426

High

1130689

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1316307

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.426

High

151352

IDLC
Axonemal dynein light intermediate polypeptide 1

2

0

High-throughput

0.324

High

363334

FINC
Fibronectin

1

0

High-throughput

0.279

Low

1067640

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1342569

ENY2
Transcription and mRNA export factor ENY2

1

0

High-throughput

0.279

Low

1354230

EMC9
ER membrane protein complex subunit 9

1

0

High-throughput

0.279

Low

489629

OSTP
Osteopontin

1

0

Small-scale

0.251

Low

715009

PROF2
Profilin-2

1

0

High-throughput

0.249

Low

721679

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

824491

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1172106

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1198024

CLC14
C-type lectin domain family 14 member A

1

0

Small-scale

0.249

Low

1252045

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

581882

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.232

Low

968662

TAGL
Transgelin

1

0

High-throughput

0.232

Low

1134786

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024