Protein: NFIX
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)

Gene: NFIX
Organism: Homo sapiens
Interactions: 204
UniProt ID: Q14938

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

135119

NFIB
Nuclear factor 1 B-type

5

14

Small-scale

0.925

High

1060288

NFIX
Nuclear factor 1 X-type

1

13

High-throughput

0.698

High

443190

NFIC
Nuclear factor 1 C-type

1

13

High-throughput

0.691

High

1018223

NFIA
Nuclear factor 1 A-type

1

13

High-throughput

0.691

High

1035435

SMAD4
Mothers against decapentaplegic homolog 4

1

7

High-throughput

0.691

High

1060298

QRIC1
Transcriptional regulator QRICH1

3

10

High-throughput

0.675

High

271766

PRDM1
PR domain zinc finger protein 1

2

5

Small-scale

0.595

High

818059

SOX2
Transcription factor SOX-2

2

20

High-throughput

0.595

High

3191

A0A0S2Z4H3
Nuclear factor 1 B-type

1

13

High-throughput

0.590

High

980754

TLE3
Transducin-like enhancer protein 3

2

20

High-throughput

0.584

High

1021110

FOXC1
Forkhead box protein C1

2

20

High-throughput

0.584

High

1060359

CIC
Protein capicua homolog

2

20

High-throughput

0.584

High

776321

MLH1
DNA mismatch repair protein Mlh1

2

0

High-throughput

0.580

High

1060329

ZN614
Zinc finger protein 614

1

1

High-throughput

0.573

High

632734

TYY1
Transcriptional repressor protein YY1

1

5

High-throughput

0.561

High

818805

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.561

High

988763

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.561

High

175970

FOXN1
Forkhead box protein N1

1

20

High-throughput

0.536

High

402019

JUN
Transcription factor Jun

1

11

High-throughput

0.536

High

877734

FOXA1
Hepatocyte nuclear factor 3-alpha

1

20

High-throughput

0.536

High

981246

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

3

High-throughput

0.536

High

986911

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.536

High

556868

CREB1
Cyclic AMP-responsive element-binding protein 1

1

4

High-throughput

0.515

High

1060308

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

8

High-throughput

0.508

High

211858

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.501

High

213337

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.501

High

225745

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.501

High

620155

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.501

High

641412

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.501

High

727745

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.501

High

727871

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.501

High

881803

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.501

High

973852

PAX2
Paired box protein Pax-2

1

20

High-throughput

0.501

High

1060295

TBR1
T-box brain protein 1

1

11

High-throughput

0.501

High

1060334

SP7
Transcription factor Sp7

1

14

High-throughput

0.501

High

1060346

LHX4
LIM/homeobox protein Lhx4

1

16

High-throughput

0.501

High

1060367

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.501

High

776689

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.493

High

521271

SKI
Ski oncogene

1

0

Small-scale

0.480

High

124209

TAF4
Transcription initiation factor TFIID subunit 4

1

14

High-throughput

0.479

High

146223

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

149861

RFXK
DNA-binding protein RFXANK

1

9

High-throughput

0.479

High

152648

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

164227

ZN609
Zinc finger protein 609

1

17

High-throughput

0.479

High

165678

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

High-throughput

0.479

High

167158

ZN536
Zinc finger protein 536

1

1

High-throughput

0.479

High

170368

TIF1A
Transcription intermediary factor 1-alpha

1

7

High-throughput

0.479

High

183116

KDM6A
Lysine-specific demethylase 6A

1

9

High-throughput

0.479

High

231239

ZEB2
Zinc finger E-box-binding homeobox 2

1

9

High-throughput

0.479

High

245604

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

14

High-throughput

0.479

High

260381

ZN217
Zinc finger protein 217

1

2

High-throughput

0.479

High

261511

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

265650

E2F6
Transcription factor E2F6

1

6

High-throughput

0.479

High

321773

WIZ
Protein Wiz

1

6

High-throughput

0.479

High

345438

FOS
Protein c-Fos

1

11

High-throughput

0.479

High

473514

ATX1L
Ataxin-1-like

1

9

High-throughput

0.479

High

486911

MYBB
Myb-related protein B

1

3

High-throughput

0.479

High

487440

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

501054

IRF1
Interferon regulatory factor 1

1

4

Small-scale

0.479

High

515593

SRF
Serum response factor

1

1

High-throughput

0.479

High

525316

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

10

High-throughput

0.479

High

540847

PO2F1
POU domain, class 2, transcription factor 1

1

14

High-throughput

0.479

High

550390

ZEP1
Zinc finger protein 40

1

8

High-throughput

0.479

High

575441

EGR1
Early growth response protein 1

1

5

High-throughput

0.479

High

610162

RFX1
MHC class II regulatory factor RFX1

1

10

Small-scale

0.479

High

631427

BRD2
Bromodomain-containing protein 2

1

11

High-throughput

0.479

High

692137

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

741052

ZEB1
Zinc finger E-box-binding homeobox 1

1

4

High-throughput

0.479

High

764648

CUX1
Homeobox protein cut-like 1

1

18

High-throughput

0.479

High

817564

RFX5
DNA-binding protein RFX5

1

4

High-throughput

0.479

High

824017

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

846776

SMCA2
Probable global transcription activator SNF2L2

1

7

High-throughput

0.479

High

855912

ZN131
Zinc finger protein 131

1

2

High-throughput

0.479

High

856020

ZN143
Zinc finger protein 143

1

1

High-throughput

0.479

High

868495

ATX1
Ataxin-1

1

9

High-throughput

0.479

High

878408

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.479

High

917280

H4
Histone H4

1

5

High-throughput

0.479

High

964183

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.479

High

966243

TFAP4
Transcription factor AP-4

1

2

High-throughput

0.479

High

975253

KMT2A
Histone-lysine N-methyltransferase 2A

1

20

High-throughput

0.479

High

980606

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

987770

GABPA
GA-binding protein alpha chain

1

20

High-throughput

0.479

High

987973

RING1
E3 ubiquitin-protein ligase RING1

1

15

High-throughput

0.479

High

993425

TLE5
TLE family member 5

1

11

High-throughput

0.479

High

1017296

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

1025103

RLF
Zinc finger protein Rlf

1

4

High-throughput

0.479

High

1036581

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

1038384

HDAC1
Histone deacetylase 1

1

4

Small-scale

0.479

High

1050503

TFDP1
Transcription factor Dp-1

1

1

High-throughput

0.479

High

1057257

SMC1A
Structural maintenance of chromosomes protein 1A

1

3

High-throughput

0.479

High

1060289

RBBP5
Retinoblastoma-binding protein 5

1

12

High-throughput

0.479

High

1060290

TAF5
Transcription initiation factor TFIID subunit 5

1

11

High-throughput

0.479

High

1060291

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1060292

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

1

High-throughput

0.479

High

1060293

ZFHX3
Zinc finger homeobox protein 3

1

7

High-throughput

0.479

High

1060299

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1060300

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

4

High-throughput

0.479

High

1060301

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

1

High-throughput

0.479

High

1060304

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

1060305

NIPBL
Nipped-B-like protein

1

18

High-throughput

0.479

High

1060307

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

1060310

NFRKB
Nuclear factor related to kappa-B-binding protein

1

9

High-throughput

0.479

High

1060311

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

11

High-throughput

0.479

High

1060312

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

9

High-throughput

0.479

High

1060313

BCOR
BCL-6 corepressor

1

12

High-throughput

0.479

High

1060314

SRCAP
Helicase SRCAP

1

9

High-throughput

0.479

High

1060315

PAXI1
PAX-interacting protein 1

1

12

High-throughput

0.479

High

1060316

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1060317

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.479

High

1060319

I2BP2
Interferon regulatory factor 2-binding protein 2

1

4

High-throughput

0.479

High

1060320

PB1
Protein polybromo-1

1

9

High-throughput

0.479

High

1060321

ZFHX4
Zinc finger homeobox protein 4

1

4

High-throughput

0.479

High

1060323

I2BP1
Interferon regulatory factor 2-binding protein 1

1

4

High-throughput

0.479

High

1060324

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.479

High

1060325

MGAP
MAX gene-associated protein

1

11

High-throughput

0.479

High

1060328

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.479

High

1060330

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

1060331

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

1060332

KDM2B
Lysine-specific demethylase 2B

1

8

High-throughput

0.479

High

1060333

SMRC2
SWI/SNF complex subunit SMARCC2

1

19

High-throughput

0.479

High

1060337

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

4

High-throughput

0.479

High

1060338

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1060339

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1060340

RREB1
Ras-responsive element-binding protein 1

1

2

High-throughput

0.479

High

1060341

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

1060342

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

1060343

KAT2A
Histone acetyltransferase KAT2A

1

12

High-throughput

0.479

High

1060344

SMRC1
SWI/SNF complex subunit SMARCC1

1

18

High-throughput

0.479

High

1060345

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

17

High-throughput

0.479

High

1060347

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

11

High-throughput

0.479

High

1060348

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

5

High-throughput

0.479

High

1060349

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

4

High-throughput

0.479

High

1060350

ZBT10
Zinc finger and BTB domain-containing protein 10

1

6

High-throughput

0.479

High

1060351

MCRS1
Microspherule protein 1

1

1

High-throughput

0.479

High

1060352

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

9

High-throughput

0.479

High

1060353

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

4

High-throughput

0.479

High

1060355

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

8

High-throughput

0.479

High

1060357

ZN512
Zinc finger protein 512

1

3

High-throughput

0.479

High

1060358

PHF12
PHD finger protein 12

1

10

High-throughput

0.479

High

1060360

MINT
Msx2-interacting protein

1

6

High-throughput

0.479

High

1060361

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

1060362

PCGF1
Polycomb group RING finger protein 1

1

9

High-throughput

0.479

High

1060364

SP130
Histone deacetylase complex subunit SAP130

1

14

High-throughput

0.479

High

1060365

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.479

High

1060366

ZN644
Zinc finger protein 644

1

7

High-throughput

0.479

High

1060368

CSR2B
Cysteine-rich protein 2-binding protein

1

3

High-throughput

0.479

High

1060369

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

8

High-throughput

0.479

High

1060373

BRD7
Bromodomain-containing protein 7

1

8

High-throughput

0.479

High

1060374

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

1060377

ZBT40
Zinc finger and BTB domain-containing protein 40

1

1

High-throughput

0.479

High

1060378

ING3
Inhibitor of growth protein 3

1

5

High-throughput

0.479

High

1060379

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

20

High-throughput

0.479

High

1060380

CXXC1
CXXC-type zinc finger protein 1

1

16

High-throughput

0.479

High

1060381

KANL3
KAT8 regulatory NSL complex subunit 3

1

1

High-throughput

0.479

High

1060382

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

3

High-throughput

0.479

High

1060383

TRPS1
Zinc finger transcription factor Trps1

1

12

High-throughput

0.479

High

1060384

DACH1
Dachshund homolog 1

1

1

High-throughput

0.479

High

1060385

SIX4
Homeobox protein SIX4

1

5

High-throughput

0.479

High

1060386

ZN608
Zinc finger protein 608

1

14

High-throughput

0.479

High

1060387

PRR12
Proline-rich protein 12

1

19

High-throughput

0.479

High

1060388

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

1060389

SATB2
DNA-binding protein SATB2

1

3

High-throughput

0.479

High

1060390

SMC3
Structural maintenance of chromosomes protein 3

1

3

High-throughput

0.479

High

1060391

ZN148
Zinc finger protein 148

1

9

High-throughput

0.479

High

1060392

ZN281
Zinc finger protein 281

1

7

High-throughput

0.479

High

1060394

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

3

High-throughput

0.479

High

1060396

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

1060397

ZHX2
Zinc fingers and homeoboxes protein 2

1

6

High-throughput

0.479

High

1060398

MORC2
ATPase MORC2

1

1

High-throughput

0.479

High

134705

PIR
Pirin

1

0

Small-scale

0.460

High

124330

RFXAP
Regulatory factor X-associated protein

1

0

High-throughput

0.458

High

224436

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

317437

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.458

High

414290

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.458

High

836222

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.458

High

1060294

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.458

High

1060296

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.458

High

1060306

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.458

High

1060327

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.458

High

1060336

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1060354

ZN521
Zinc finger protein 521

1

0

High-throughput

0.458

High

1060371

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.458

High

1060372

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.458

High

1060375

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

1060376

SALL1
Sal-like protein 1

1

0

High-throughput

0.458

High

1060393

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

717836

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.445

High

1060302

Q5VW31
Nuclear factor I B

1

12

High-throughput

0.445

High

397971

ISG15
Ubiquitin-like protein ISG15

1

7

High-throughput

0.437

High

1016363

TF3C1
General transcription factor 3C polypeptide 1

1

1

High-throughput

0.437

High

1057812

GSE1
Genetic suppressor element 1

1

4

High-throughput

0.437

High

1060297

QSER1
Glutamine and serine-rich protein 1

1

20

High-throughput

0.437

High

1060303

ZMYM4
Zinc finger MYM-type protein 4

1

3

High-throughput

0.437

High

1060318

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

17

High-throughput

0.437

High

1060322

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

9

High-throughput

0.437

High

1060356

EP400
E1A-binding protein p400

1

8

High-throughput

0.437

High

1060363

DDA1
DET1- and DDB1-associated protein 1

1

3

High-throughput

0.437

High

1060395

TF3C3
General transcription factor 3C polypeptide 3

1

9

High-throughput

0.437

High

969050

GCYB1
Guanylate cyclase soluble subunit beta-1

1

0

Small-scale

0.249

Low

1060309

MSD2
Myb/SANT-like DNA-binding domain-containing protein 2

1

0

High-throughput

0.249

Low

1060326

BAP18
Chromatin complexes subunit BAP18

1

0

High-throughput

0.249

Low

1060335

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.249

Low

1060370

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024