Protein: ELOC
Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)

Gene: ELOC
Organism: Homo sapiens
Interactions: 221
UniProt ID: Q15369

Gene Ontology (top 5):
GO:0001222 - transcription corepressor binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

771976

VHL
von Hippel-Lindau disease tumor suppressor

55

1

Small-scale

0.996

High

1072220

ELOB
Elongin-B

25

4

Small-scale

0.991

High

1072271

CUL5
Cullin-5

22

5

Small-scale

0.989

High

1041329

CUL2
Cullin-2

17

5

Small-scale

0.986

High

1072279

ASB9
Ankyrin repeat and SOCS box protein 9

10

8

Small-scale

0.972

High

181868

SOCS1
Suppressor of cytokine signaling 1

9

10

Small-scale

0.966

High

146630

SOCS2
Suppressor of cytokine signaling 2

7

10

Small-scale

0.960

High

1017272

RB40B
Ras-related protein Rab-40B

7

6

Small-scale

0.960

High

1072273

SPSB4
SPRY domain-containing SOCS box protein 4

5

6

Small-scale

0.933

High

1072341

ASB3
Ankyrin repeat and SOCS box protein 3

5

4

Small-scale

0.925

High

147523

SOCS6
Suppressor of cytokine signaling 6

5

10

Small-scale

0.919

High

1072309

ASB8
Ankyrin repeat and SOCS box protein 8

5

6

Small-scale

0.919

High

1072293

SPSB2
SPRY domain-containing SOCS box protein 2

4

6

Small-scale

0.910

High

1072321

ASB6
Ankyrin repeat and SOCS box protein 6

4

3

Small-scale

0.894

High

1072289

ASB2
Ankyrin repeat and SOCS box protein 2

4

4

Small-scale

0.874

High

1072290

RB40C
Ras-related protein Rab-40C

3

6

Small-scale

0.873

High

1041630

CUL3
Cullin-3

3

6

High-throughput

0.864

High

1072260

RB40A
Ras-related protein Rab-40A

3

6

High-throughput

0.861

High

1072274

SPSB1
SPRY domain-containing SOCS box protein 1

3

6

Small-scale

0.849

High

1072342

ASB1
Ankyrin repeat and SOCS box protein 1

3

11

Small-scale

0.829

High

1072343

WSB1
WD repeat and SOCS box-containing protein 1

3

1

Small-scale

0.829

High

1072259

SOCS4
Suppressor of cytokine signaling 4

3

10

Small-scale

0.821

High

469818

RB40L
Ras-related protein Rab-40A-like

2

6

High-throughput

0.789

High

475797

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

2

Small-scale

0.768

High

227522

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.754

High

1072223

NEDD8
NEDD8

2

0

Small-scale

0.748

High

1072226

HIF1A
Hypoxia-inducible factor 1-alpha

9

2

Small-scale

0.745

High

256854

SOCS5
Suppressor of cytokine signaling 5

2

10

Small-scale

0.743

High

1051946

ELOA1
Elongin-A

7

5

Small-scale

0.739

High

147428

SOCS3
Suppressor of cytokine signaling 3

6

10

Small-scale

0.736

High

1072327

NRBP
Nuclear receptor-binding protein

4

2

Small-scale

0.699

High

943716

PRAME
Melanoma antigen preferentially expressed in tumors

3

3

Small-scale

0.688

High

1072295

KLDC3
Kelch domain-containing protein 3

4

2

Small-scale

0.683

High

1072235

MT21C
Protein-lysine methyltransferase METTL21C

4

0

High-throughput

0.668

High

1072335

KLDC2
Kelch domain-containing protein 2

3

3

Small-scale

0.667

High

921275

RBX1
E3 ubiquitin-protein ligase RBX1

3

2

Small-scale

0.660

High

529154

CFTR
Cystic fibrosis transmembrane conductance regulator

4

0

High-throughput

0.658

High

1072328

FEM1B
Protein fem-1 homolog B

3

2

Small-scale

0.656

High

1072258

ASB11
Ankyrin repeat and SOCS box protein 11

1

5

Small-scale

0.647

High

929474

RACK1
Small ribosomal subunit protein RACK1

3

0

Small-scale

0.636

High

1072246

CSN6
COP9 signalosome complex subunit 6

3

0

High-throughput

0.634

High

244476

BRD4
Bromodomain-containing protein 4

3

0

Small-scale

0.619

High

63589

ASB14
Ankyrin repeat and SOCS box protein 14

1

4

High-throughput

0.618

High

1072243

ASB18
Ankyrin repeat and SOCS box protein 18

1

6

High-throughput

0.618

High

1072257

ASB5
Ankyrin repeat and SOCS box protein 5

1

10

High-throughput

0.618

High

1072261

ASB10
Ankyrin repeat and SOCS box protein 10

1

6

High-throughput

0.618

High

1072262

ASB15
Ankyrin repeat and SOCS box protein 15

1

4

High-throughput

0.618

High

1072263

ASB13
Ankyrin repeat and SOCS box protein 13

1

6

High-throughput

0.618

High

1072264

ASB12
Ankyrin repeat and SOCS box protein 12

1

6

High-throughput

0.618

High

1072288

ASB16
Ankyrin repeat and SOCS box protein 16

1

7

High-throughput

0.618

High

1072307

ASB7
Ankyrin repeat and SOCS box protein 7

1

5

High-throughput

0.618

High

1072315

CISH
Cytokine-inducible SH2-containing protein

1

10

Small-scale

0.618

High

1072297

NEUL2
Neuralized-like protein 2

1

0

Small-scale

0.614

High

1047440

PEBB
Core-binding factor subunit beta

3

0

Small-scale

0.613

High

299378

UBXN7
UBX domain-containing protein 7

2

1

Small-scale

0.611

High

312609

ARI2
E3 ubiquitin-protein ligase ARIH2

2

2

Small-scale

0.611

High

1072239

CTR9
RNA polymerase-associated protein CTR9 homolog

2

1

High-throughput

0.611

High

1072286

LLR1
Leucine-rich repeat protein 1

2

1

Small-scale

0.611

High

1072323

RBX2
RING-box protein 2

2

2

Small-scale

0.602

High

1072276

ANKR9
Ankyrin repeat domain-containing protein 9

2

0

Small-scale

0.602

High

1072247

ZER1
Protein zer-1 homolog

2

5

Small-scale

0.600

High

1072270

CSN5
COP9 signalosome complex subunit 5

2

0

High-throughput

0.585

High

1072284

DCNL1
DCN1-like protein 1

2

0

Small-scale

0.585

High

1072305

CHM4B
Charged multivesicular body protein 4b

2

1

High-throughput

0.584

High

1072251

COMD1
COMM domain-containing protein 1

2

0

Small-scale

0.577

High

1043361

CUL4B
Cullin-4B

1

5

High-throughput

0.575

High

369656

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1065771

LRC14
Leucine-rich repeat-containing protein 14

2

3

High-throughput

0.571

High

1072255

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

2

0

Small-scale

0.569

High

1072283

MED8
Mediator of RNA polymerase II transcription subunit 8

1

1

Small-scale

0.562

High

970573

ID2
DNA-binding protein inhibitor ID-2

1

2

Small-scale

0.561

High

1071595

LRC41
Leucine-rich repeat-containing protein 41

2

0

Small-scale

0.559

High

1072265

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

0

Small-scale

0.559

High

1072282

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

1072252

ARI1B
AT-rich interactive domain-containing protein 1B

1

0

Small-scale

0.537

High

1072248

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

1

High-throughput

0.536

High

1072278

FAF2
FAS-associated factor 2

1

1

High-throughput

0.536

High

1072294

EPAS1
Endothelial PAS domain-containing protein 1

1

2

High-throughput

0.536

High

1072298

FEM1A
Protein fem-1 homolog A

1

2

High-throughput

0.536

High

1072313

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.536

High

1072291

NOTC4
Neurogenic locus notch homolog protein 4

1

0

Small-scale

0.527

High

800388

CBX5
Chromobox protein homolog 5

1

0

High-throughput

0.518

High

975497

CENPC
Centromere protein C

1

0

High-throughput

0.518

High

1072233

CPTP
Ceramide-1-phosphate transfer protein

1

0

High-throughput

0.518

High

975260

KMT2A
Histone-lysine N-methyltransferase 2A

1

1

Small-scale

0.515

High

62820

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

0

High-throughput

0.513

High

813489

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

1072225

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.513

High

1072269

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1072320

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

1072303

ZY11B
Protein zyg-11 homolog B

1

5

Small-scale

0.508

High

1072250

ELOA2
Elongin-A2

1

5

Small-scale

0.501

High

884637

CORO7
Coronin-7

1

0

Small-scale

0.493

High

1069201

TCAL1
Transcription elongation factor A protein-like 1

1

0

High-throughput

0.493

High

1072228

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.493

High

63027

LR14B
Leucine-rich repeat-containing protein 14B

1

3

High-throughput

0.489

High

1072316

NRBP2
Nuclear receptor-binding protein 2

1

2

High-throughput

0.489

High

708922

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.480

High

64532

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

1

Small-scale

0.479

High

278814

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.479

High

374270

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

488724

ARAF
Serine/threonine-protein kinase A-Raf

1

1

High-throughput

0.479

High

528373

MYH6
Myosin-6

1

1

High-throughput

0.479

High

569761

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

649114

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

2

High-throughput

0.479

High

780967

ID1
DNA-binding protein inhibitor ID-1

1

2

Small-scale

0.479

High

971121

ID3
DNA-binding protein inhibitor ID-3

1

2

Small-scale

0.479

High

985670

CTSL2
CTD small phosphatase-like protein 2

1

1

High-throughput

0.479

High

1033477

ILK
Integrin-linked protein kinase

1

1

High-throughput

0.479

High

1072221

T22D1
TSC22 domain family protein 1

1

1

High-throughput

0.479

High

1072224

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1072231

SGO1
Shugoshin 1

1

1

High-throughput

0.479

High

1072236

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1072240

SPSB3
SPRY domain-containing SOCS box protein 3

1

6

Small-scale

0.479

High

1072241

BCOR
BCL-6 corepressor

1

2

High-throughput

0.479

High

1072267

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1072281

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.479

High

1072301

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

1

High-throughput

0.479

High

1072318

DJC11
DnaJ homolog subfamily C member 11

1

1

High-throughput

0.479

High

1072330

CSN3
COP9 signalosome complex subunit 3

1

1

High-throughput

0.479

High

1072337

FBX7
F-box only protein 7

1

1

High-throughput

0.479

High

1072339

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

1072340

ARI1
E3 ubiquitin-protein ligase ARIH1

1

2

High-throughput

0.479

High

1072310

ECT2
Protein ECT2

1

0

High-throughput

0.460

High

125474

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

148851

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

182766

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

294860

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

303260

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

345084

CYTA
Cystatin-A

1

0

High-throughput

0.458

High

396739

S10A8
Protein S100-A8

1

0

High-throughput

0.458

High

505638

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

509010

TOP2A
DNA topoisomerase 2-alpha

1

0

Small-scale

0.458

High

651273

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

718510

NOS2
Nitric oxide synthase, inducible

1

0

Small-scale

0.458

High

720529

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

724438

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

726837

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

779461

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

798904

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

807734

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

874102

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.458

High

880735

HDAC4
Histone deacetylase 4

1

0

High-throughput

0.458

High

896102

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

897737

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

908586

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

917311

H4
Histone H4

1

0

High-throughput

0.458

High

927955

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

0

High-throughput

0.458

High

958192

RBM3
RNA-binding protein 3

1

0

Small-scale

0.458

High

967878

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1031200

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

1036594

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

1056501

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

Small-scale

0.458

High

1064323

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1066150

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1071871

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1072227

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1072230

CENPW
Centromere protein W

1

0

Small-scale

0.458

High

1072234

PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

1

0

High-throughput

0.458

High

1072237

TET2
Methylcytosine dioxygenase TET2

1

0

Small-scale

0.458

High

1072238

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1072245

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

1072249

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1072254

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.458

High

1072256

DNJA4
DnaJ homolog subfamily A member 4

1

0

High-throughput

0.458

High

1072266

APBP2
Amyloid protein-binding protein 2

1

0

Small-scale

0.458

High

1072275

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.458

High

1072277

SGK3
Serine/threonine-protein kinase Sgk3

1

0

High-throughput

0.458

High

1072292

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1072296

MBB1A
Myb-binding protein 1A

1

0

Small-scale

0.458

High

1072299

PCGF1
Polycomb group RING finger protein 1

1

0

High-throughput

0.458

High

1072300

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.458

High

1072302

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1072308

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1072311

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1072312

MOV10
Helicase MOV-10

1

0

Small-scale

0.458

High

1072314

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

Small-scale

0.458

High

1072324

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

0

Small-scale

0.458

High

1072325

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1072329

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1072332

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.458

High

1072333

FBW1A
F-box/WD repeat-containing protein 1A

1

0

Small-scale

0.458

High

581165

EPOR
Erythropoietin receptor

1

1

Small-scale

0.457

High

241239

PRAM2
PRAME family member 2

1

3

Small-scale

0.437

High

1072322

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1072338

T22D4
TSC22 domain family protein 4

1

1

High-throughput

0.437

High

378057

PRIO
Major prion protein

1

0

High-throughput

0.426

High

497066

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

882311

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

1072232

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

500967

GHR
Growth hormone receptor

1

1

Small-scale

0.408

High

831346

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

156095

RASM
Ras-related protein M-Ras

1

0

High-throughput

0.282

High

283646

JTB
Protein JTB

1

0

High-throughput

0.282

High

847943

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.282

High

881898

WNT7B
Protein Wnt-7b

1

0

High-throughput

0.282

High

1051729

RCAN2
Calcipressin-2

1

0

High-throughput

0.282

High

1072222

EFNB3
Ephrin-B3

1

0

High-throughput

0.282

High

1072326

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.282

High

1072229

SETMR
Histone-lysine N-methyltransferase SETMAR

1

0

High-throughput

0.279

Low

1072334

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

239584

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.269

Low

1072272

EXT2
Exostosin-2

1

0

High-throughput

0.269

Low

1072280

SAT2
Thialysine N-epsilon-acetyltransferase

1

0

Small-scale

0.261

Low

100783

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

429048

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.249

Low

1044340

PTC1
Protein patched homolog 1

1

0

Small-scale

0.249

Low

1072242

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1072244

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1072253

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1072268

IOD2
Type II iodothyronine deiodinase

1

0

Small-scale

0.249

Low

1072285

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1072287

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.249

Low

1072304

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.249

Low

1072306

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1072317

PCMD2
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

1

0

Small-scale

0.249

Low

1072319

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1072336

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

230625

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low

240006

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

1072331

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024