Protein: PTN11
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2)

Gene: PTN11, Ptpn11
Organism: Rattus norvegicus
Interactions: 12
UniProt ID: P41499

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0001784 - phosphotyrosine residue binding
GO:0004721 - phosphoprotein phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0004726 - non-membrane spanning protein tyrosine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

835037

T2CB11
Tyrosine-protein kinase receptor

2

20

Small-scale

0.754

High

835036

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.646

High

835031

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.618

High

835033

JAK2
Tyrosine-protein kinase JAK2

1

20

Small-scale

0.618

High

835034

NTRK2
BDNF/NT-3 growth factors receptor

1

20

Small-scale

0.618

High

835035

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

8

Small-scale

0.618

High

835032

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

10

Small-scale

0.589

High

93207

D4A244
Fibroblast growth factor receptor substrate 2

2

6

Small-scale

0.584

High

98917

F1MAL5
Insulin receptor substrate 2

1

9

Small-scale

0.500

High

81602

B5DFH3
Protein sprouty homolog 1

1

1

Small-scale

0.479

High

98699

F1LST4
Microtubule-associated protein

1

3

Small-scale

0.479

High

772587

IRS1
Insulin receptor substrate 1

1

9

Small-scale

0.479

High


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Last updated: 11Aug2025