HitPredict

Interactor 1: TSC2 (P49815)
Tuberin (Tuberous sclerosis 2 protein)
Gene: TSC2

Interactor 2: RAP1A (P62834)
Ras-related protein Rap-1A (EC 3.6.5.2) (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1)
Gene: RAP1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 12842888, 12147258
Identification Methods affinity chromatography technology, biochemical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rap_GAP~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031267 - small GTPase binding
GO:0048471 - perinuclear region of cytoplasm
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1807
Hs

1 184
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024