HitPredict

Interactor 1: TSC2 (P49815)
Tuberin (Tuberous sclerosis 2 protein)
Gene: TSC2

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30297842
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1807 Hs			1 196
+	Hs
		915714 RGPA2_HUMAN (1358-1777): 9.62e-131: 454: 21.70		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		951036 RGPA2_HUMAN (1358-1777): 9.62e-131: 454: 21.70		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		564550 RGPA2_HUMAN (1358-1777): 9.62e-131: 454: 21.70		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		925359 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900583 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915756 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		951081 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		892432 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		894131 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564573 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120494 RGPA1_HUMAN (1385-1780): 1.79e-109: 390: 20.74		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		196428 SI1L1_HUMAN (1451-1805): 8.9e-92: 333: 22.83		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		916041 SI1L2_HUMAN (1459-1800): 2.08e-79: 293: 20.17		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		230233 SI1L3_HUMAN (1459-1807): 3.43e-77: 286: 21.33		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		230232 SI1L3_HUMAN (1459-1807): 3.43e-77: 286: 21.33		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		925514 SIPA1_HUMAN (1258-1800): 6.13e-74: 271: 18.39		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900790 SIPA1_HUMAN (1258-1800): 6.13e-74: 271: 18.39		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Dm
		776929 X2JDH0_DROME (1477-1754): 1.11e-59: 230: 23.37		RAC1_DROME (1-196): 1.58e-77: 231: 53.06
+	Dm
		776932 X2JJU0_DROME (1477-1754): 1.09e-59: 230: 23.37		RAC1_DROME (1-196): 1.58e-77: 231: 53.06