Protein: EGR1
Early growth response protein 1 (EGR-1) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor Zif268) (Zinc finger protein Krox-24)

Gene: EGR1
Organism: Mus musculus
Interactions: 24
UniProt ID: P08046

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313390

SP1
Transcription factor Sp1

1

17

Small-scale

0.665

High

464760

SRF
Serum response factor

3

3

Small-scale

0.640

High

464743

EGR1
Early growth response protein 1

1

18

High-throughput

0.621

High

464758

CDK9
Cyclin-dependent kinase 9

1

2

Small-scale

0.618

High

464747

ELK1
ETS domain-containing protein Elk-1

2

8

Small-scale

0.584

High

92662

D3YZC9
Splicing factor 1

1

1

Small-scale

0.552

High

464752

NAB2
NGFI-A-binding protein 2

1

6

High-throughput

0.541

High

373661

MYC
Myc proto-oncogene protein

1

8

Small-scale

0.479

High

464746

ELK4
ETS domain-containing protein Elk-4

1

9

Small-scale

0.479

High

464748

ELK3
ETS domain-containing protein Elk-3

1

8

Small-scale

0.479

High

464750

PITX1
Pituitary homeobox 1

1

8

Small-scale

0.479

High

464751

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

Small-scale

0.479

High

464754

SMAD3
Mothers against decapentaplegic homolog 3

1

5

Small-scale

0.479

High

464755

EPHB1
Ephrin type-B receptor 1

1

6

Small-scale

0.479

High

464756

DMTF1
Cyclin-D-binding Myb-like transcription factor 1

1

2

Small-scale

0.479

High

464759

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

1

Small-scale

0.479

High

464745

TBP
TATA-box-binding protein

1

0

Small-scale

0.458

High

464749

TF2B
Transcription initiation factor IIB

1

0

Small-scale

0.458

High

464753

ARF
Tumor suppressor ARF

1

0

Small-scale

0.458

High

464757

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

0

Small-scale

0.458

High

464761

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.458

High

464762

MBD2
Methyl-CpG-binding domain protein 2

1

0

Small-scale

0.458

High

464744

SAMP
Serum amyloid P-component

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025