Protein: SP1
Transcription factor Sp1 (Specificity protein 1)

Gene: SP1
Organism: Mus musculus
Interactions: 37
UniProt ID: O89090

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313390

EGR1
Early growth response protein 1

1

17

Small-scale

0.665

High

267156

SP3
Transcription factor Sp3

1

17

Small-scale

0.647

High

148634

HDAC1
Histone deacetylase 1

2

20

Small-scale

0.624

High

313409

CSK21
Casein kinase II subunit alpha

1

13

Small-scale

0.618

High

313411

E2F1
Transcription factor E2F1

2

9

Small-scale

0.611

High

313395

PO5F1
POU domain, class 5, transcription factor 1

2

10

Small-scale

0.611

High

313402

MK14
Mitogen-activated protein kinase 14

1

10

High-throughput

0.590

High

313412

JAK3
Tyrosine-protein kinase JAK3

2

7

Small-scale

0.584

High

313416

BHE41
Class E basic helix-loop-helix protein 41

1

1

Small-scale

0.573

High

313414

NANOG
Homeobox protein NANOG

1

14

Small-scale

0.554

High

236467

CSK22
Casein kinase II subunit alpha'

1

13

Small-scale

0.553

High

313403

CEBPG
CCAAT/enhancer-binding protein gamma

1

15

Small-scale

0.515

High

313400

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.501

High

313413

ARF
Tumor suppressor ARF

1

0

Small-scale

0.493

High

313388

P53
Cellular tumor antigen p53

1

8

Small-scale

0.479

High

313389

JUN
Transcription factor Jun

1

9

Small-scale

0.479

High

313397

MDM2
E3 ubiquitin-protein ligase Mdm2

1

3

Small-scale

0.479

High

313398

TNR5
Tumor necrosis factor receptor superfamily member 5

1

8

Small-scale

0.479

High

313399

CEBPB
CCAAT/enhancer-binding protein beta

1

13

Small-scale

0.479

High

313401

STAT3
Signal transducer and activator of transcription 3

1

4

Small-scale

0.479

High

313404

PRS8
26S proteasome regulatory subunit 8

1

7

Small-scale

0.479

High

313405

MSX3
Homeobox protein MSX-3

1

18

Small-scale

0.479

High

313406

CREB1
Cyclic AMP-responsive element-binding protein 1

1

3

Small-scale

0.479

High

313407

TF65
Transcription factor p65

1

14

Small-scale

0.479

High

313408

SOX8
Transcription factor SOX-8

1

11

Small-scale

0.479

High

313410

NR0B1
Nuclear receptor subfamily 0 group B member 1

1

20

Small-scale

0.479

High

313415

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

313418

Q9JM08
Histone deacetylase

1

19

Small-scale

0.479

High

313419

SRBP1
Sterol regulatory element-binding protein 1

1

20

Small-scale

0.479

High

313420

MECP2
Methyl-CpG-binding protein 2

1

8

Small-scale

0.479

High

313392

BCL2
Apoptosis regulator Bcl-2

1

0

Small-scale

0.458

High

313417

OGA
Protein O-GlcNAcase

1

0

Small-scale

0.458

High

313393

FGL2
Fibroleukin

1

1

Small-scale

0.437

High

313394

LYAM1
L-selectin

1

1

Small-scale

0.437

High

313396

MFGM
Lactadherin

1

14

Small-scale

0.437

High

313421

Z4YJL0
Bromo adjacent homology domain containing 1

1

1

Small-scale

0.437

High

313391

CCL2
C-C motif chemokine 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025