Protein: SH3G2
Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4)

Gene: SH3G2, Sh3gl2
Organism: Mus musculus
Interactions: 23
UniProt ID: Q62420

Gene Ontology (top 5):
GO:0002090 - regulation of receptor internalization
GO:0005769 - early endosome
GO:0008289 - lipid binding
GO:0010629 - negative regulation of gene expression
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

810526

DYN1
Dynamin-1

3

20

Small-scale

0.840

High

1224168

PRKN
E3 ubiquitin-protein ligase parkin

1

18

Small-scale

0.770

High

1224161

SH3G2
Endophilin-A1

1

16

Small-scale

0.692

High

92772

D3Z656
Synaptojanin-1

3

20

Small-scale

0.667

High

147420

BIN1
Myc box-dependent-interacting protein 1

1

20

Small-scale

0.647

High

1224163

AMPH
Amphiphysin

1

20

Small-scale

0.647

High

1193759

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

15

High-throughput

0.575

High

1223548

DLG4
Disks large homolog 4

1

9

High-throughput

0.575

High

1013600

TNIK
Traf2 and NCK-interacting protein kinase

1

20

High-throughput

0.536

High

266847

ATX2
Ataxin-2

1

20

Small-scale

0.515

High

1224165

DEN1A
DENN domain-containing protein 1A

1

13

Small-scale

0.515

High

1224164

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

10

High-throughput

0.514

High

205281

RASD1
Dexamethasone-induced Ras-related protein 1

1

11

Small-scale

0.508

High

108713

G3X9H5
Huntingtin

1

11

Small-scale

0.501

High

313064

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.479

High

958593

DRD2
D(2) dopamine receptor

1

20

Small-scale

0.479

High

1224166

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

Small-scale

0.479

High

313177

SYN1
Synapsin-1

1

20

Small-scale

0.457

High

1191074

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

6

High-throughput

0.437

High

1222256

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

20

Small-scale

0.437

High

1224167

PDC6I
Programmed cell death 6-interacting protein

1

20

Small-scale

0.417

High

1224162

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025