Interactor 1: SH3G2 (Q62420)
Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4)
Gene: Sh3gl2
Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.59 | 1.00 | 0.770 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20064468 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, pull down, enzymatic study |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH3_1~ubiquitin |
| Common GO terms | GO:0010629 - negative regulation of gene expression GO:0048471 - perinuclear region of cytoplasm GO:0098978 - glutamatergic synapse |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
