Protein: CDKA1
Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor)

Gene: CDKA1, CDK2AP1
Organism: Homo sapiens
Interactions: 120
UniProt ID: O14519

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001934 - positive regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

146816

HDAC1
Histone deacetylase 1

8

6

Small-scale

0.750

High

146822

RBBP7
Histone-binding protein RBBP7

8

4

Small-scale

0.748

High

146817

CHD4
Chromodomain-helicase-DNA-binding protein 4

7

9

Small-scale

0.745

High

146847

HDAC2
Histone deacetylase 2

7

6

Small-scale

0.745

High

146782

CDKA2
Cyclin-dependent kinase 2-associated protein 2

1

2

Small-scale

0.740

High

146810

RBBP4
Histone-binding protein RBBP4

6

6

Small-scale

0.732

High

146832

P66A
Transcriptional repressor p66-alpha

6

3

Small-scale

0.732

High

146846

P66B
Transcriptional repressor p66-beta

6

3

Small-scale

0.732

High

146876

ZN219
Zinc finger protein 219

5

2

High-throughput

0.718

High

146812

CHD3
Chromodomain-helicase-DNA-binding protein 3

5

9

Small-scale

0.716

High

146786

MBD3
Methyl-CpG-binding domain protein 3

5

5

Small-scale

0.712

High

146877

MBD2
Methyl-CpG-binding domain protein 2

5

5

Small-scale

0.712

High

146859

MTA3
Metastasis-associated protein MTA3

5

8

Small-scale

0.706

High

146784

MTA2
Metastasis-associated protein MTA2

4

8

Small-scale

0.691

High

146815

MTA1
Metastasis-associated protein MTA1

4

8

Small-scale

0.683

High

146845

MB3L1
Methyl-CpG-binding domain protein 3-like 1

3

5

High-throughput

0.667

High

146851

MR1L1
MORF4 family-associated protein 1-like 1

5

2

High-throughput

0.661

High

146885

STRAP
Serine-threonine kinase receptor-associated protein

2

2

High-throughput

0.628

High

146838

ZBTB2
Zinc finger and BTB domain-containing protein 2

2

1

High-throughput

0.611

High

146841

CHD5
Chromodomain-helicase-DNA-binding protein 5

2

9

High-throughput

0.611

High

146862

BC11B
B-cell lymphoma/leukemia 11B

2

4

High-throughput

0.611

High

146881

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

2

2

High-throughput

0.584

High

146837

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.580

High

146850

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

146865

CARD9
Caspase recruitment domain-containing protein 9

2

0

High-throughput

0.580

High

146872

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

146874

SPG21
Maspardin

2

0

High-throughput

0.580

High

146883

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

2

0

High-throughput

0.580

High

146769

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

2

Small-scale

0.575

High

146789

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

146800

CDK2
Cyclin-dependent kinase 2

1

0

Small-scale

0.537

High

146772

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

2

High-throughput

0.536

High

146773

HDAC3
Histone deacetylase 3

1

6

High-throughput

0.536

High

146776

IMA7
Importin subunit alpha-7

1

2

High-throughput

0.536

High

146778

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

2

High-throughput

0.536

High

146785

PHF14
PHD finger protein 14

1

1

High-throughput

0.536

High

146803

IMA5
Importin subunit alpha-5

1

2

High-throughput

0.536

High

146831

RAI1
Retinoic acid-induced protein 1

1

1

High-throughput

0.536

High

146835

ZN687
Zinc finger protein 687

1

2

High-throughput

0.536

High

146858

MEP50
Methylosome protein WDR77

1

2

High-throughput

0.536

High

146860

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

2

High-throughput

0.536

High

146878

TCF20
Transcription factor 20

1

1

High-throughput

0.536

High

146880

TRPS1
Zinc finger transcription factor Trps1

1

3

High-throughput

0.536

High

146791

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.513

High

146795

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.513

High

146796

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.513

High

146806

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.513

High

146823

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

146824

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

High-throughput

0.513

High

146834

DDX60
Probable ATP-dependent RNA helicase DDX60

1

0

High-throughput

0.513

High

146844

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.513

High

146848

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.513

High

146866

ESF1
ESF1 homolog

1

0

High-throughput

0.513

High

146868

CSN7B
COP9 signalosome complex subunit 7b

1

0

High-throughput

0.513

High

146871

HM20A
High mobility group protein 20A

1

0

High-throughput

0.513

High

146884

SHLB1
Endophilin-B1

1

0

High-throughput

0.513

High

146792

DPOLA
DNA polymerase alpha catalytic subunit

1

0

Small-scale

0.480

High

146774

PHF1
PHD finger protein 1

1

1

High-throughput

0.479

High

146775

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

9

High-throughput

0.479

High

146777

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

146779

SIN3B
Paired amphipathic helix protein Sin3b

1

1

High-throughput

0.479

High

146781

EED
Polycomb protein EED

1

3

High-throughput

0.479

High

146783

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.479

High

146790

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

146798

CBL
E3 ubiquitin-protein ligase CBL

1

1

High-throughput

0.479

High

146801

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

146802

SMCA1
Probable global transcription activator SNF2L1

1

9

High-throughput

0.479

High

146809

ERCC6
DNA excision repair protein ERCC-6

1

10

High-throughput

0.479

High

146811

BPTF
Nucleosome-remodeling factor subunit BPTF

1

7

High-throughput

0.479

High

146814

CAF1B
Chromatin assembly factor 1 subunit B

1

3

High-throughput

0.479

High

146818

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

10

High-throughput

0.479

High

146820

BRD3
Bromodomain-containing protein 3

1

4

High-throughput

0.479

High

146827

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

1

High-throughput

0.479

High

146842

ZN296
Zinc finger protein 296

1

4

High-throughput

0.479

High

146853

Z512B
Zinc finger protein 512B

1

1

High-throughput

0.479

High

146856

PHF12
PHD finger protein 12

1

9

High-throughput

0.479

High

146857

SIN3A
Paired amphipathic helix protein Sin3a

1

1

High-throughput

0.479

High

146864

BC11A
B-cell lymphoma/leukemia 11A

1

4

High-throughput

0.479

High

146867

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

1

High-throughput

0.479

High

146886

MTF2
Metal-response element-binding transcription factor 2

1

1

High-throughput

0.479

High

146840

ZN420
Zinc finger protein 420

1

0

High-throughput

0.460

High

146770

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

146771

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

146780

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.458

High

146794

MYBB
Myb-related protein B

1

0

High-throughput

0.458

High

146804

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

146805

H4
Histone H4

1

0

High-throughput

0.458

High

146808

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

146813

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.458

High

146819

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

146821

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

146825

ARI4B
AT-rich interactive domain-containing protein 4B

1

0

High-throughput

0.458

High

146826

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.458

High

146828

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

146829

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

146830

BCOR
BCL-6 corepressor

1

0

High-throughput

0.458

High

146833

BAP18
Chromatin complexes subunit BAP18

1

0

High-throughput

0.458

High

146836

PGBD3
PiggyBac transposable element-derived protein 3

1

0

High-throughput

0.458

High

146839

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.458

High

146843

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

146849

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

146854

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

146855

PWP2A
PWWP domain-containing protein 2A

1

0

High-throughput

0.458

High

146861

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

146863

SP130
Histone deacetylase complex subunit SAP130

1

0

High-throughput

0.458

High

146869

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

146882

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.458

High

91455

E7EQY4
Metastasis associated 1 family member 3

1

8

High-throughput

0.445

High

146807

CSK2B
Casein kinase II subunit beta

1

0

Small-scale

0.438

High

146787

IGHA1
Immunoglobulin heavy constant alpha 1

1

1

High-throughput

0.437

High

146788

IGHA2
Immunoglobulin heavy constant alpha 2

1

1

High-throughput

0.437

High

146875

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.426

High

146852

CC136
Coiled-coil domain-containing protein 136

2

0

High-throughput

0.330

High

146799

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

0

High-throughput

0.279

Low

146870

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.279

Low

146797

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

146793

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.249

Low

146873

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low

146879

HMGX4
HMG domain-containing protein 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024