Protein: ACY2
Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2)

Gene: ACY2, ASPA
Organism: Homo sapiens
Interactions: 16
UniProt ID: P45381

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006083 - acetate metabolic process
GO:0006531 - aspartate metabolic process
GO:0016788 - hydrolase activity, acting on ester bonds

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

852134

ACY3
N-acyl-aromatic-L-amino acid amidohydrolase

4

4

High-throughput

0.917

High

852129

ACY2
Aspartoacylase

2

4

Small-scale

0.800

High

852132

DUS29
Dual specificity phosphatase 29

2

0

High-throughput

0.580

High

852135

RUFY1
RUN and FYVE domain-containing protein 1

1

1

High-throughput

0.536

High

297503

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.515

High

852133

UBQLN
Ubiquilin-like protein

1

2

High-throughput

0.515

High

852136

UBQL3
Ubiquilin-3

1

2

High-throughput

0.515

High

852137

UBQL2
Ubiquilin-2

1

2

High-throughput

0.515

High

133643

WASL
Actin nucleation-promoting factor WASL

1

0

High-throughput

0.513

High

451683

PGK2
Phosphoglycerate kinase 2

1

0

High-throughput

0.513

High

852131

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.506

High

852138

CSN3
COP9 signalosome complex subunit 3

1

0

High-throughput

0.493

High

404716

PRIO
Major prion protein

1

0

High-throughput

0.426

High

852130

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.282

High

105517

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025