Protein: HUNK
Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (B19) (Serine/threonine-protein kinase MAK-V)

Gene: HUNK
Organism: Homo sapiens
Interactions: 108
UniProt ID: P57058

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0007165 - signal transduction
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

943611

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

2

3

High-throughput

0.817

High

922240

LIMK1
LIM domain kinase 1

2

16

Small-scale

0.793

High

658877

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

4

High-throughput

0.698

High

727745

DNJA1
DnaJ homolog subfamily A member 1

1

5

High-throughput

0.698

High

828190

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

13

High-throughput

0.698

High

943571

DYST
Dystonin

1

6

High-throughput

0.698

High

943575

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

12

High-throughput

0.698

High

943596

ZN655
Zinc finger protein 655

1

1

High-throughput

0.698

High

943598

DP13B
DCC-interacting protein 13-beta

1

11

High-throughput

0.698

High

943613

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

3

High-throughput

0.698

High

943621

ARP8
Actin-related protein 8

1

4

High-throughput

0.698

High

943623

SH2B1
SH2B adapter protein 1

1

13

High-throughput

0.698

High

943628

KS6A6
Ribosomal protein S6 kinase alpha-6

1

16

High-throughput

0.691

High

244078

ZN292
Zinc finger protein 292

1

1

High-throughput

0.625

High

783693

ZNF76
Zinc finger protein 76

1

2

High-throughput

0.625

High

943565

RAB5B
Ras-related protein Rab-5B

1

9

High-throughput

0.625

High

943566

VISL1
Visinin-like protein 1

1

14

High-throughput

0.625

High

943591

ZN662
Zinc finger protein 662

1

1

High-throughput

0.625

High

943597

ZBT44
Zinc finger and BTB domain-containing protein 44

1

2

High-throughput

0.625

High

943614

MCHR1
Melanin-concentrating hormone receptor 1

1

3

High-throughput

0.625

High

605614

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

19

High-throughput

0.618

High

651634

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

19

High-throughput

0.618

High

717742

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

8

Small-scale

0.618

High

161535

ZN197
Zinc finger protein 197

1

0

High-throughput

0.584

High

472560

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.584

High

943587

ZN343
Zinc finger protein 343

1

0

High-throughput

0.584

High

943590

ZN793
Zinc finger protein 793

1

0

High-throughput

0.584

High

124761

AIP
AH receptor-interacting protein

1

5

High-throughput

0.541

High

159174

ABLM1
Actin-binding LIM protein 1

1

2

High-throughput

0.541

High

287893

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

3

High-throughput

0.541

High

443738

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

5

High-throughput

0.541

High

614673

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

5

High-throughput

0.541

High

627947

ANXA7
Annexin A7

1

3

High-throughput

0.541

High

639697

TAF1
Transcription initiation factor TFIID subunit 1

1

9

High-throughput

0.541

High

838905

AK1C3
Aldo-keto reductase family 1 member C3

1

1

High-throughput

0.541

High

921850

COPA
Coatomer subunit alpha

1

1

High-throughput

0.541

High

943572

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

High-throughput

0.541

High

943573

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.541

High

943585

TRI68
E3 ubiquitin-protein ligase TRIM68

1

3

High-throughput

0.541

High

943589

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

4

High-throughput

0.541

High

943602

IFT81
Intraflagellar transport protein 81 homolog

1

8

High-throughput

0.541

High

943604

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.541

High

943606

TTC28
Tetratricopeptide repeat protein 28

1

3

High-throughput

0.541

High

943608

MOAP1
Modulator of apoptosis 1

1

8

High-throughput

0.541

High

943615

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

5

High-throughput

0.541

High

943617

SRBS1
Sorbin and SH3 domain-containing protein 1

1

9

High-throughput

0.541

High

943618

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

9

High-throughput

0.541

High

943622

PICK1
PRKCA-binding protein

1

3

High-throughput

0.541

High

943624

SMYD2
N-lysine methyltransferase SMYD2

1

2

High-throughput

0.541

High

943629

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.541

High

943630

CHIP
E3 ubiquitin-protein ligase CHIP

1

5

High-throughput

0.541

High

943632

KIF3A
Kinesin-like protein KIF3A

1

4

High-throughput

0.541

High

943633

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

2

High-throughput

0.541

High

943567

GRB2
Growth factor receptor-bound protein 2

1

15

High-throughput

0.536

High

943625

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.536

High

943631

TPPC4
Trafficking protein particle complex subunit 4

1

1

High-throughput

0.536

High

943634

TPPC1
Trafficking protein particle complex subunit 1

1

1

High-throughput

0.536

High

138468

BIN1
Myc box-dependent-interacting protein 1

1

0

High-throughput

0.518

High

460478

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.518

High

533630

CLUS
Clusterin

1

0

High-throughput

0.518

High

599568

STMN1
Stathmin

1

0

High-throughput

0.518

High

884499

SYAC
Alanine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.518

High

943576

SPRL1
SPARC-like protein 1

1

0

High-throughput

0.518

High

943609

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.518

High

943610

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.518

High

943616

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.518

High

943619

PITH1
PITH domain-containing protein 1

1

0

High-throughput

0.518

High

943626

MTMRA
Myotubularin-related protein 10

1

0

High-throughput

0.518

High

660012

COF1
Cofilin-1

1

4

Small-scale

0.515

High

874024

TPC10
Trafficking protein particle complex subunit 10

1

0

High-throughput

0.513

High

943594

TPC6B
Trafficking protein particle complex subunit 6B

1

0

High-throughput

0.513

High

943612

TPPC9
Trafficking protein particle complex subunit 9

1

0

High-throughput

0.513

High

194538

KDM6A
Lysine-specific demethylase 6A

1

3

High-throughput

0.494

High

522402

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.494

High

635250

EFNA1
Ephrin-A1

1

1

High-throughput

0.494

High

720386

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

5

High-throughput

0.494

High

787955

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.494

High

943569

OLR1
Oxidized low-density lipoprotein receptor 1

1

1

High-throughput

0.494

High

943574

IFT88
Intraflagellar transport protein 88 homolog

1

2

High-throughput

0.494

High

943580

NDF2
Neurogenic differentiation factor 2

1

2

High-throughput

0.494

High

943581

GEN
Flap endonuclease GEN homolog 1

1

1

High-throughput

0.494

High

943588

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.494

High

943595

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

3

High-throughput

0.494

High

943600

DI3L1
DIS3-like exonuclease 1

1

1

High-throughput

0.494

High

943620

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

4

High-throughput

0.494

High

943627

MBD1
Methyl-CpG-binding domain protein 1

1

3

High-throughput

0.494

High

943635

MAGD1
Melanoma-associated antigen D1

1

4

High-throughput

0.494

High

943599

LNX1
E3 ubiquitin-protein ligase LNX

1

10

Small-scale

0.481

High

943568

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

11

Small-scale

0.479

High

943579

RABE1
Rab GTPase-binding effector protein 1

1

4

Small-scale

0.439

High

943583

ARMX4
Armadillo repeat-containing X-linked protein 4

1

3

High-throughput

0.417

High

552933

PIP
Prolactin-inducible protein

2

0

High-throughput

0.313

High

567741

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.282

High

852130

ACY2
Aspartoacylase

1

0

High-throughput

0.282

High

896683

ASCL1
Achaete-scute homolog 1

1

0

High-throughput

0.282

High

932985

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.282

High

943577

COG2
Conserved oligomeric Golgi complex subunit 2

1

0

High-throughput

0.282

High

943578

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.282

High

943582

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.282

High

943584

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.282

High

943586

SNR48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

1

0

High-throughput

0.282

High

943592

CXXC5
CXXC-type zinc finger protein 5

1

0

High-throughput

0.282

High

943593

VP35L
VPS35 endosomal protein-sorting factor-like

1

0

High-throughput

0.282

High

943603

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.282

High

943605

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

0

High-throughput

0.282

High

943607

TOM6
Mitochondrial import receptor subunit TOM6 homolog

1

0

High-throughput

0.282

High

943601

TPC14
Trafficking protein particle complex subunit 14

1

0

High-throughput

0.279

Low

943570

H11
Histone H1.1

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025