Protein: XIAP
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP homolog A) (Inhibitor of apoptosis protein 3) (IAP-3) (mIAP-3) (mIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)

Gene: XIAP
Organism: Mus musculus
Interactions: 17
UniProt ID: Q60989

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1141991

DBLOH
Diablo IAP-binding mitochondrial protein

3

11

Small-scale

0.827

High

476824

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

15

High-throughput

0.647

High

957027

CASP7
Caspase-7

1

20

Small-scale

0.621

High

936913

CASP3
Caspase-3

1

20

Small-scale

0.618

High

1141992

HTRA2
Serine protease HTRA2, mitochondrial

2

15

Small-scale

0.595

High

139406

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.561

High

864287

CCHL
Holocytochrome c-type synthase

1

2

Small-scale

0.534

High

1141988

TGFR1
TGF-beta receptor type-1

1

6

Small-scale

0.515

High

1141993

MAGD1
Melanoma-associated antigen D1

1

5

Small-scale

0.501

High

659544

SEPT4
Septin-4

1

6

Small-scale

0.479

High

925796

RAC1
Ras-related C3 botulinum toxin substrate 1

1

11

Small-scale

0.479

High

966323

NOTC1
Neurogenic locus notch homolog protein 1

1

15

Small-scale

0.479

High

1110680

STING
Stimulator of interferon genes protein

1

5

High-throughput

0.479

High

1141989

NEB2
Neurabin-2

1

4

High-throughput

0.479

High

1141990

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

14

Small-scale

0.479

High

1141987

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.457

High

103631

G5E8L8
Mitogen-activated protein kinase kinase kinase 2

1

8

Small-scale

0.437

High


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Last updated: 15 Jul 2024