Protein: HCK
Tyrosine-protein kinase HCK (EC 2.7.10.2) (B-cell/myeloid kinase) (BMK) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK/p59-HCK)

Gene: HCK
Organism: Mus musculus
Interactions: 14
UniProt ID: P08103

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

465765

HCK
Tyrosine-protein kinase HCK

3

20

Small-scale

0.789

High

465767

CBL
E3 ubiquitin-protein ligase CBL

3

20

Small-scale

0.678

High

465773

SH21C
SH2 domain-containing protein 1B2

1

20

Small-scale

0.553

High

108397

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

465768

FCGR1
High affinity immunoglobulin gamma Fc receptor I

1

15

Small-scale

0.479

High

465770

WASP
Actin nucleation-promoting factor WAS

1

20

Small-scale

0.479

High

465774

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

Small-scale

0.479

High

465775

FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

0.479

High

465772

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

465766

ITB1
Integrin beta-1

1

14

Small-scale

0.445

High

465769

CSF3R
Granulocyte colony-stimulating factor receptor

1

14

Small-scale

0.437

High

465771

LIRB3
Paired immunoglobulin-like receptor B

1

20

Small-scale

0.437

High

465776

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

4

High-throughput

0.437

High


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Last updated: 11Aug2025