Protein: KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)

Gene: KCC2A, Camk2a
Organism: Mus musculus
Interactions: 60
UniProt ID: P11798

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0002931 - response to ischemia
GO:0004674 - protein serine/threonine kinase activity
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

515229

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

3

10

High-throughput

0.847

High

515214

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

16

Small-scale

0.757

High

515226

NMDE2
Glutamate receptor ionotropic, NMDA 2B

7

15

Small-scale

0.731

High

515225

RGS14
Regulator of G-protein signaling 14

1

4

High-throughput

0.724

High

515254

ACTN2
Alpha-actinin-2

1

6

Small-scale

0.724

High

57825

KALRN
Kalirin

1

8

High-throughput

0.691

High

292112

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

13

High-throughput

0.691

High

515224

TNIK
Traf2 and NCK-interacting protein kinase

1

11

High-throughput

0.691

High

515228

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

8

High-throughput

0.691

High

515242

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.691

High

515244

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

15

High-throughput

0.691

High

515240

NEB2
Neurabin-2

4

20

Small-scale

0.680

High

99901

SYGP1
Ras/Rap GTPase-activating protein SynGAP

3

11

High-throughput

0.667

High

515234

DLG4
Disks large homolog 4

3

15

High-throughput

0.667

High

515233

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

Small-scale

0.665

High

515217

NMDZ1
Glutamate receptor ionotropic, NMDA 1

3

15

Small-scale

0.633

High

222823

ACK1
Activated CDC42 kinase 1

1

10

Small-scale

0.618

High

515213

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

3

High-throughput

0.618

High

515216

ACM4
Muscarinic acetylcholine receptor M4

1

3

Small-scale

0.618

High

515238

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

3

High-throughput

0.590

High

515259

BAG6
Large proline-rich protein BAG6

1

3

High-throughput

0.590

High

192649

CAN1
Calpain-1 catalytic subunit

1

14

Small-scale

0.575

High

515220

CDK5
Cyclin-dependent kinase 5

1

7

Small-scale

0.575

High

515223

IRF3
Interferon regulatory factor 3

1

0

Small-scale

0.554

High

515230

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

5

High-throughput

0.536

High

515232

FXR1
RNA-binding protein FXR1

1

18

High-throughput

0.536

High

515241

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

5

High-throughput

0.536

High

515243

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.536

High

515245

MYOME
Myomegalin

1

1

High-throughput

0.536

High

515249

PEX5R
PEX5-related protein

1

7

High-throughput

0.536

High

515252

DLGP1
Disks large-associated protein 1

1

9

High-throughput

0.536

High

515253

TSC1
Hamartin

1

6

High-throughput

0.536

High

515261

HOME1
Homer protein homolog 1

1

0

High-throughput

0.513

High

515246

RHG32
Rho GTPase-activating protein 32

1

5

Small-scale

0.501

High

515215

NCKP1
Nck-associated protein 1

1

1

High-throughput

0.489

High

250512

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

0

Small-scale

0.480

High

92888

PRRT2
Proline-rich transmembrane protein 2

1

2

High-throughput

0.479

High

102757

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

192906

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

5

High-throughput

0.479

High

292461

SYN1
Synapsin-1

1

2

Small-scale

0.479

High

515221

1433Z
14-3-3 protein zeta/delta

1

19

High-throughput

0.479

High

515227

TRI72
Tripartite motif-containing protein 72

1

3

Small-scale

0.479

High

515231

PPP5
Serine/threonine-protein phosphatase 5

1

13

High-throughput

0.479

High

515236

INADL
InaD-like protein

1

17

Small-scale

0.479

High

515247

Q8BPK8
Agenet-like domain-containing protein

1

18

High-throughput

0.479

High

515260

MECP2
Methyl-CpG-binding protein 2

1

4

Small-scale

0.479

High

515248

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.458

High

222319

O54737
BCA protein

1

2

High-throughput

0.457

High

515222

IMB1
Importin subunit beta-1

1

3

High-throughput

0.457

High

515237

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

1

5

High-throughput

0.457

High

515250

ABI1
Abl interactor 1

1

7

High-throughput

0.457

High

515255

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

11

High-throughput

0.457

High

515218

FMR1
Fragile X messenger ribonucleoprotein 1

1

18

High-throughput

0.445

High

515256

SRCN1
SRC kinase signaling inhibitor 1

1

4

High-throughput

0.445

High

515219

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

1

0

High-throughput

0.438

High

515235

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

5

Small-scale

0.437

High

515257

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.437

High

515251

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

2

High-throughput

0.417

High

515258

PDC6I
Programmed cell death 6-interacting protein

1

2

High-throughput

0.417

High

515239

GPBP1
Vasculin

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024