HitPredict

Interactor 1: HCK (P08103)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (B-cell/myeloid kinase) (BMK) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p56-HCK/p59-HCK)
Gene: HCK

Interactor 2: ITB1 (P09055)
Integrin beta-1 (Fibronectin receptor subunit beta) (VLA-4 subunit beta) (CD antigen CD29)
Gene: Itgb1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19903482
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 524 Mm			1 798
+	Mm
		478492 FGR_MOUSE (11-522): 0: 590: 56.29		ITB1_MOUSE (1-798): 0: 826: 100.00
+	Hs
		431659 LYN_HUMAN (22-524): 0: 571: 69.92		ITB1_HUMAN (1-798): 0: 820: 92.48
+	Mm
		362434 ABL1_MOUSE (42-521): 2.06e-174: 523: 39.34		ITB1_MOUSE (1-798): 0: 826: 100.00
+	Mm
		236548 SRC_MOUSE (26-522): 0: 592: 57.52		ITB3_MOUSE (23-797): 0: 684: 44.16
+	Rn
		1057712 LYN_RAT (22-524): 0: 575: 69.92		ITB3_RAT (23-797): 0: 679: 43.39
+	Hs
		424051 LYN_HUMAN (22-524): 0: 571: 69.92		ITB2_HUMAN (20-796): 0: 683: 45.07
+	Hs
		424003 SRC_HUMAN (26-522): 0: 592: 57.11		ITB3_HUMAN (25-797): 0: 656: 43.89
+	Hs
		423995 LYN_HUMAN (22-524): 0: 571: 69.92		ITB3_HUMAN (25-797): 0: 656: 43.89
+	Hs
		362118 ABL1_HUMAN (42-521): 2e-174: 523: 39.34		ITB2_HUMAN (20-796): 0: 683: 45.07
+	Dm
		262710 ABL_DROME (55-517): 8.99e-171: 525: 40.59		TENM_DROME (472-738): 1.46e-39: 160: 20.22
+	Hs
		439989 LCK_HUMAN (22-524): 0: 591: 64.24		NOTC1_HUMAN (345-630): 9.81e-15: 80.9: 10.40
+	Hs
		463258 YES_HUMAN (19-522): 0: 583: 59.68		TEN1_HUMAN (364-490): 1.01e-12: 74.3: 11.36
+	Hs
		463394 LYN_HUMAN (22-524): 0: 571: 69.92		NOTC1_HUMAN (345-630): 9.81e-15: 80.9: 10.40
+	Hs
		362206 ABL1_HUMAN (42-521): 2e-174: 523: 39.34		NOTC1_HUMAN (345-630): 9.81e-15: 80.9: 10.40