Protein: SCYL2
SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa)

Gene: SCYL2
Organism: Homo sapiens
Interactions: 171
UniProt ID: Q6P3W7

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0005102 - signaling receptor binding
GO:0005524 - ATP binding
GO:0005794 - Golgi apparatus
GO:0007420 - brain development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

914146

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.754

High

414964

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.691

High

932213

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.665

High

882930

RBM11
Splicing regulator RBM11

1

2

High-throughput

0.625

High

1084496

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

5

High-throughput

0.618

High

1159496

THOC4
THO complex subunit 4

1

1

High-throughput

0.618

High

227798

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.618

High

255870

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.618

High

338568

EGFR
Epidermal growth factor receptor

1

11

High-throughput

0.618

High

385016

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

508065

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

591599

RAB3B
Ras-related protein Rab-3B

1

4

High-throughput

0.618

High

592326

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.618

High

601532

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.618

High

608015

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

884517

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.618

High

915763

RHOB
Rho-related GTP-binding protein RhoB

1

10

High-throughput

0.618

High

960295

CDK5
Cyclin-dependent kinase 5

1

1

High-throughput

0.618

High

1070254

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.618

High

1159546

ST38L
Serine/threonine-protein kinase 38-like

1

9

High-throughput

0.618

High

451474

CLCA
Clathrin light chain A

2

2

High-throughput

0.611

High

369834

ESR1
Estrogen receptor

2

9

High-throughput

0.594

High

1159521

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.578

High

609358

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.575

High

150720

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

9

Small-scale

0.561

High

130950

PSDE
26S proteasome non-ATPase regulatory subunit 14

2

3

High-throughput

0.558

High

318166

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.553

High

326687

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.553

High

564577

RHOQ
Rho-related GTP-binding protein RhoQ

1

13

High-throughput

0.553

High

591894

RAB4A
Ras-related protein Rab-4A

1

5

High-throughput

0.553

High

845551

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.553

High

900592

RHOA
Transforming protein RhoA

1

9

High-throughput

0.553

High

951087

RHOG
Rho-related GTP-binding protein RhoG

1

8

High-throughput

0.553

High

1036670

SQSTM
Sequestosome-1

1

4

High-throughput

0.553

High

1159490

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.553

High

1159498

MIB1
E3 ubiquitin-protein ligase MIB1

1

2

High-throughput

0.553

High

1159500

MIRO2
Mitochondrial Rho GTPase 2

1

14

High-throughput

0.553

High

1159525

OVOL2
Transcription factor Ovo-like 2

1

1

Small-scale

0.553

High

1159529

RHOJ
Rho-related GTP-binding protein RhoJ

1

13

High-throughput

0.553

High

1159530

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.553

High

1159540

PD1L1
Programmed cell death 1 ligand 1

1

4

Small-scale

0.553

High

1159544

UBQL2
Ubiquilin-2

1

5

High-throughput

0.553

High

1159547

NINL
Ninein-like protein

1

7

High-throughput

0.553

High

504264

HSP7C
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.536

High

685991

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

818166

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.536

High

871622

HSP72
Heat shock-related 70 kDa protein 2

1

8

High-throughput

0.536

High

873042

KAD2
Adenylate kinase 2, mitochondrial

1

1

High-throughput

0.536

High

1057058

EPN4
Clathrin interactor 1

1

2

High-throughput

0.536

High

1159523

AKAP9
A-kinase anchor protein 9

1

7

High-throughput

0.536

High

386938

P53
Cellular tumor antigen p53

2

6

Small-scale

0.533

High

802627

CRK
Adapter molecule crk

2

1

High-throughput

0.521

High

1159522

SH3G3
Endophilin-A3

2

7

High-throughput

0.521

High

960845

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1035220

FZD5
Frizzled-5

1

2

Small-scale

0.512

High

364316

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

164930

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.489

High

323839

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.489

High

611262

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.489

High

827230

ARRB1
Beta-arrestin-1

1

1

High-throughput

0.489

High

960529

PURA
Transcriptional activator protein Pur-alpha

1

2

High-throughput

0.489

High

1039635

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.489

High

1159515

TGM7
Protein-glutamine gamma-glutamyltransferase Z

1

1

High-throughput

0.489

High

1159520

CDC5L
Cell division cycle 5-like protein

1

9

High-throughput

0.489

High

1159528

NSRP1
Nuclear speckle splicing regulatory protein 1

1

2

High-throughput

0.489

High

1159539

GTSE1
G2 and S phase-expressed protein 1

1

2

High-throughput

0.489

High

205544

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

212883

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

241697

F262
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

1

1

High-throughput

0.479

High

305506

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.479

High

451695

CLCB
Clathrin light chain B

1

2

High-throughput

0.479

High

567117

CXA1
Gap junction alpha-1 protein

1

4

High-throughput

0.479

High

757655

IF4A3
Eukaryotic initiation factor 4A-III

1

2

High-throughput

0.479

High

908707

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

925914

AP2B1
AP-2 complex subunit beta

1

7

High-throughput

0.479

High

1159493

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1159499

CUL9
Cullin-9

1

3

High-throughput

0.479

High

1159504

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

4

Small-scale

0.479

High

1159506

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1159524

GORS1
Golgi reassembly-stacking protein 1

1

3

High-throughput

0.479

High

1159527

WWTR1
WW domain-containing transcription regulator protein 1

1

4

High-throughput

0.479

High

1159531

GORS2
Golgi reassembly-stacking protein 2

1

3

High-throughput

0.479

High

313551

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

3

High-throughput

0.464

High

262016

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

684822

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

1159538

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

1159543

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

0

High-throughput

0.458

High

1159518

CK5P2
CDK5 regulatory subunit-associated protein 2

1

8

High-throughput

0.445

High

117284

PDLI1
PDZ and LIM domain protein 1

1

14

High-throughput

0.437

High

132506

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

2

High-throughput

0.437

High

133530

NOP56
Nucleolar protein 56

1

1

Small-scale

0.437

High

162883

XPO1
Exportin-1

1

7

High-throughput

0.437

High

166261

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.437

High

169500

BET1
BET1 homolog

1

3

High-throughput

0.437

High

177043

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

3

Small-scale

0.437

High

178605

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

244580

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.437

High

273851

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.437

High

301876

TRI37
E3 ubiquitin-protein ligase TRIM37

1

10

High-throughput

0.437

High

443594

VIME
Vimentin

1

2

High-throughput

0.437

High

522010

CADH1
Cadherin-1

1

3

High-throughput

0.437

High

527545

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.437

High

540855

PO2F1
POU domain, class 2, transcription factor 1

1

2

Small-scale

0.437

High

552977

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

651480

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

670075

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.437

High

720724

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

781920

PERI
Peripherin

1

2

High-throughput

0.437

High

823422

PAXI
Paxillin

1

2

High-throughput

0.437

High

840501

VASP
Vasodilator-stimulated phosphoprotein

1

6

High-throughput

0.437

High

890708

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.437

High

902326

COPZ1
Coatomer subunit zeta-1

1

2

High-throughput

0.437

High

1080946

SEPT7
Septin-7

1

2

High-throughput

0.437

High

1082122

CRY1
Cryptochrome-1

1

1

High-throughput

0.437

High

1118968

AMOT
Angiomotin

1

10

High-throughput

0.437

High

1134095

UBAP2
Ubiquitin-associated protein 2

1

3

High-throughput

0.437

High

1151909

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1159489

SYNE3
Nesprin-3

1

7

High-throughput

0.437

High

1159494

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

1159497

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1159501

CNTRB
Centrobin

1

9

High-throughput

0.437

High

1159502

RHG18
Rho GTPase-activating protein 18

1

1

High-throughput

0.437

High

1159505

SMAP2
Stromal membrane-associated protein 2

1

2

High-throughput

0.437

High

1159507

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.437

High

1159508

ESR2
Estrogen receptor beta

1

9

High-throughput

0.437

High

1159510

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.437

High

1159512

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

1159514

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

1159526

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

4

High-throughput

0.437

High

1159535

SEP11
Septin-11

1

2

High-throughput

0.437

High

1159536

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

1159541

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

3

High-throughput

0.437

High

1159542

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.437

High

1159545

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.437

High

1159549

SHLB1
Endophilin-B1

1

7

High-throughput

0.437

High

1159550

RPGF2
Rap guanine nucleotide exchange factor 2

1

1

High-throughput

0.437

High

1159517

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.426

High

497190

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.407

High

1159516

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

5

High-throughput

0.407

High

601279

VDAC1
Voltage-dependent anion-selective channel protein 1

1

0

High-throughput

0.279

Low

664240

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.279

Low

725812

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

1022523

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.279

Low

1139289

SPAT1
Spermatogenesis-associated protein 1

1

0

High-throughput

0.279

Low

1159492

COX15
Heme A synthase COX15

1

0

High-throughput

0.279

Low

1159503

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.279

Low

1159513

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

1159533

DPOE3
DNA polymerase epsilon subunit 3

1

0

High-throughput

0.279

Low

122830

MEN1
Menin

1

0

High-throughput

0.249

Low

242103

PAGE4
P antigen family member 4

1

0

High-throughput

0.249

Low

298593

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

352643

TNFA
Tumor necrosis factor

1

0

High-throughput

0.249

Low

409120

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.249

Low

430227

PROF1
Profilin-1

1

0

High-throughput

0.249

Low

867218

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.249

Low

899508

MGN
Protein mago nashi homolog

1

0

High-throughput

0.249

Low

948881

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.249

Low

1072761

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

1126635

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

1146102

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1146517

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.249

Low

1148635

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1159491

MOB2
MOB kinase activator 2

1

0

High-throughput

0.249

Low

1159495

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1159509

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.249

Low

1159511

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1159519

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1159532

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

1159534

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low

1159537

FBX34
F-box only protein 34

1

0

Small-scale

0.249

Low

1159548

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024