Protein: AP2C
Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer-binding protein 2 gamma) (Transcription factor ERF-1)

Gene: AP2C, TFAP2C
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q92754

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

370131

ESR1
Estrogen receptor

4

6

Small-scale

0.666

High

1270263

CITE2
Cbp/p300-interacting transactivator 2

2

4

Small-scale

0.625

High

930326

UBC9
SUMO-conjugating enzyme UBC9

2

2

Small-scale

0.620

High

1070993

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

2

Small-scale

0.561

High

265876

NR1I2
Nuclear receptor subfamily 1 group I member 2

1

9

High-throughput

0.541

High

1270272

WWOX
WW domain-containing oxidoreductase

1

0

Small-scale

0.537

High

157068

AIM2
Interferon-inducible protein AIM2

1

2

High-throughput

0.536

High

1192065

AP2D
Transcription factor AP-2-delta

1

9

High-throughput

0.536

High

158516

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

0

High-throughput

0.518

High

851788

CCNG1
Cyclin-G1

1

0

High-throughput

0.518

High

487999

RARA
Retinoic acid receptor alpha

1

5

Small-scale

0.505

High

387218

P53
Cellular tumor antigen p53

1

2

Small-scale

0.501

High

1270260

CITE4
Cbp/p300-interacting transactivator 4

1

7

Small-scale

0.501

High

1270261

GPR22
G-protein coupled receptor 22

1

1

High-throughput

0.494

High

244726

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

347483

MYC
Myc proto-oncogene protein

1

4

Small-scale

0.479

High

403672

AP2A
Transcription factor AP-2-alpha

1

9

Small-scale

0.479

High

749731

BRCA1
Breast cancer type 1 susceptibility protein

1

1

Small-scale

0.479

High

917680

H4
Histone H4

1

2

High-throughput

0.479

High

998936

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1174578

KCTD1
BTB/POZ domain-containing protein KCTD1

1

5

Small-scale

0.479

High

301950

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

Small-scale

0.458

High

1080186

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1270275

KDM5B
Lysine-specific demethylase 5B

1

0

Small-scale

0.458

High

118590

EYA2
Eyes absent homolog 2

1

2

High-throughput

0.457

High

172694

LAMA5
Laminin subunit alpha-5

1

1

High-throughput

0.457

High

211636

ACTN4
Alpha-actinin-4

1

1

High-throughput

0.457

High

283125

CCN5
CCN family member 5

1

1

High-throughput

0.457

High

365281

MT2
Metallothionein-2

1

1

High-throughput

0.457

High

523910

XRCC6
X-ray repair cross-complementing protein 6

1

4

High-throughput

0.457

High

771440

IFI27
Interferon alpha-inducible protein 27, mitochondrial

1

3

High-throughput

0.457

High

823076

AGRE5
Adhesion G protein-coupled receptor E5

1

1

High-throughput

0.457

High

946740

TMF1
TATA element modulatory factor

1

1

High-throughput

0.457

High

1050736

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.457

High

1076492

TRIP6
Thyroid receptor-interacting protein 6

1

3

High-throughput

0.457

High

1080742

ZYX
Zyxin

1

3

High-throughput

0.457

High

1270259

RMD5B
E3 ubiquitin-protein transferase RMND5B

1

1

High-throughput

0.457

High

1270267

I27L2
Interferon alpha-inducible protein 27-like protein 2

1

3

High-throughput

0.457

High

620540

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

1

Small-scale

0.445

High

268806

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.438

High

383500

PRM2
Protamine-2

1

0

High-throughput

0.438

High

542985

FABP4
Fatty acid-binding protein, adipocyte

1

0

High-throughput

0.438

High

623156

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.438

High

644114

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.438

High

670375

AQP1
Aquaporin-1

1

0

High-throughput

0.438

High

682196

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.438

High

786493

STAT6
Signal transducer and activator of transcription 6

1

0

High-throughput

0.438

High

862445

ACLY
ATP-citrate synthase

1

0

High-throughput

0.438

High

900053

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.438

High

928788

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.438

High

932806

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.438

High

991173

TISB
mRNA decay activator protein ZFP36L1

1

0

High-throughput

0.438

High

1049499

SAFB2
Scaffold attachment factor B2

1

0

High-throughput

0.438

High

1164856

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.438

High

1262688

ATX2L
Ataxin-2-like protein

1

0

High-throughput

0.438

High

1270256

FUBP2
Far upstream element-binding protein 2

1

0

High-throughput

0.438

High

1270258

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.438

High

1270262

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.438

High

1270266

SHRPN
Sharpin

1

0

High-throughput

0.438

High

1270268

JUPI2
Jupiter microtubule associated homolog 2

1

0

High-throughput

0.438

High

1270270

PLS3
Phospholipid scramblase 3

1

0

High-throughput

0.438

High

1270271

MA2C1
Alpha-mannosidase 2C1

1

0

High-throughput

0.438

High

1270273

UXT
Protein UXT

1

0

High-throughput

0.438

High

1270277

SRTD3
SERTA domain-containing protein 3

1

0

High-throughput

0.438

High

1270278

FLVC1
Heme transporter FLVCR1

1

0

High-throughput

0.438

High

313980

PPN
Papilin

1

1

High-throughput

0.417

High

328026

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

8

High-throughput

0.417

High

358546

CO1A1
Collagen alpha-1(I) chain

1

4

High-throughput

0.417

High

358639

CO3A1

1

4

High-throughput

0.417

High

363245

FINC
Fibronectin

1

2

High-throughput

0.417

High

436041

CO1A2
Collagen alpha-2(I) chain

1

4

High-throughput

0.417

High

441762

CFAH
Complement factor H

1

3

High-throughput

0.417

High

518026

CO6A2

1

3

High-throughput

0.417

High

556469

ITB4
Integrin beta-4

1

2

High-throughput

0.417

High

604227

TENX
Tenascin-X

1

6

High-throughput

0.417

High

612893

FBLN1
Fibulin-1

1

10

High-throughput

0.417

High

657682

LYOX
Protein-lysine 6-oxidase

1

2

High-throughput

0.417

High

760513

COFA1
Collagen alpha-1(XV) chain [Cleaved into: Restin

1

6

High-throughput

0.417

High

957280

FBLN2
Fibulin-2

1

10

High-throughput

0.417

High

995490

LOXL1
Lysyl oxidase homolog 1

1

2

High-throughput

0.417

High

1016980

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

7

High-throughput

0.417

High

1081913

TENXA
Putative tenascin-XA

1

4

High-throughput

0.417

High

1176308

CCD80
Coiled-coil domain-containing protein 80

1

1

High-throughput

0.417

High

1270269

CD248
Endosialin

1

8

High-throughput

0.417

High

1270274

FBLN5
Fibulin-5

1

8

High-throughput

0.417

High

1270276

DPP2
Dipeptidyl peptidase 2

1

1

High-throughput

0.417

High

1270279

FCGBP
IgGFc-binding protein

1

3

High-throughput

0.417

High

1204243

ZFAN4
AN1-type zinc finger protein 4

1

0

High-throughput

0.282

High

170558

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

1

0

High-throughput

0.238

Low

1229981

SHSA5
Protein shisa-5

1

0

High-throughput

0.238

Low

1270257

CTHR1
Collagen triple helix repeat-containing protein 1

1

0

High-throughput

0.238

Low

1270264

APOL4
Apolipoprotein L4

1

0

High-throughput

0.238

Low

1270265

WDR83
WD repeat domain-containing protein 83

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024