HitPredict

Interactor 1: STXB3 (O00186)
Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C)
Gene: STXBP3

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Hs			1 192
+	Hs
		119609 STXB3_HUMAN (1-592): 0: 679: 100.00		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		119607 STXB3_HUMAN (1-592): 0: 679: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		119666 STXB3_HUMAN (1-592): 0: 679: 100.00		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		119622 STXB3_HUMAN (1-592): 0: 679: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		119629 STXB3_HUMAN (1-592): 0: 679: 100.00		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		119623 STXB3_HUMAN (1-592): 0: 679: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		119624 STXB3_HUMAN (1-592): 0: 679: 100.00		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		119604 STXB3_HUMAN (1-592): 0: 679: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		925654 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		545641 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		1330938 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892619 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		951382 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		894486 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900953 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436530 VPS45_HUMAN (18-576): 1.26e-146: 437: 19.04		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		545528 SCFD1_HUMAN (23-582): 6.54e-138: 417: 15.82		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		892512 SCFD1_HUMAN (23-582): 6.54e-138: 417: 15.82		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		894257 SCFD1_HUMAN (23-582): 6.54e-138: 417: 15.82		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		436433 SCFD1_HUMAN (23-582): 6.54e-138: 417: 15.82		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45