Protein: NDKB
Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2)

Gene: NDKB, NME2
Organism: Homo sapiens
Interactions: 215
UniProt ID: P22392

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
GO:0004550 - nucleoside diphosphate kinase activity
GO:0004673 - protein histidine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548860

NDKA
Nucleoside diphosphate kinase A

7

17

Small-scale

0.957

High

607647

NDK3
Nucleoside diphosphate kinase 3

5

17

Small-scale

0.929

High

607586

NDKB
Nucleoside diphosphate kinase B

4

16

Small-scale

0.884

High

135574

NDKM
Nucleoside diphosphate kinase, mitochondrial

3

17

High-throughput

0.849

High

226526

PRKN
E3 ubiquitin-protein ligase parkin

3

8

Small-scale

0.656

High

496304

TAU
Microtubule-associated protein tau

3

3

High-throughput

0.650

High

368986

ESR1
Estrogen receptor

3

5

Small-scale

0.633

High

361821

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

2

High-throughput

0.611

High

362645

A2GL
Leucine-rich alpha-2-glycoprotein

2

1

High-throughput

0.611

High

394123

A4
Amyloid-beta precursor protein

2

4

High-throughput

0.611

High

607626

NPC2
NPC intracellular cholesterol transporter 2

2

2

High-throughput

0.611

High

607664

CCNG2
Cyclin-G2

2

4

High-throughput

0.611

High

607732

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.611

High

607721

TRABD
TraB domain-containing protein

3

1

High-throughput

0.599

High

499528

CH60
60 kDa heat shock protein, mitochondrial

2

6

High-throughput

0.584

High

607617

TERA
Transitional endoplasmic reticulum ATPase

2

3

High-throughput

0.584

High

607614

ACLY
ATP-citrate synthase

2

0

Small-scale

0.576

High

233739

NDK8
Putative nucleoside diphosphate kinase

1

16

High-throughput

0.575

High

607668

Q32Q12
Nucleoside diphosphate kinase

1

16

High-throughput

0.575

High

607630

RS6
Small ribosomal subunit protein eS6

2

1

High-throughput

0.571

High

607690

RHG24
Rho GTPase-activating protein 24

2

3

High-throughput

0.571

High

607701

PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

2

2

High-throughput

0.571

High

607727

RHG35
Rho GTPase-activating protein 35

2

4

High-throughput

0.571

High

152732

ITBP1
Integrin beta-1-binding protein 1

1

0

Small-scale

0.561

High

607723

WDR76
WD repeat-containing protein 76

2

0

High-throughput

0.559

High

607736

HERC5
E3 ISG15--protein ligase HERC5

1

3

Small-scale

0.552

High

607609

DYN2
Dynamin-2

1

5

Small-scale

0.550

High

607642

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.549

High

607673

HRG1
Heme transporter HRG1

2

1

High-throughput

0.549

High

607696

DOCK8
Dedicator of cytokinesis protein 8

2

0

High-throughput

0.547

High

607611

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.541

High

198400

KLK10
Kallikrein-10

1

5

High-throughput

0.536

High

474922

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

7

High-throughput

0.536

High

562624

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

1

High-throughput

0.536

High

607623

ARP2
Actin-related protein 2

1

1

High-throughput

0.536

High

607636

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.536

High

607640

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.536

High

607641

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

3

High-throughput

0.536

High

607712

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

3

High-throughput

0.536

High

607719

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

2

High-throughput

0.536

High

607722

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

3

High-throughput

0.536

High

592101

RAB5A
Ras-related protein Rab-5A

1

0

High-throughput

0.518

High

607650

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.518

High

156221

PSA7
Proteasome subunit alpha type-7

1

3

High-throughput

0.515

High

607588

PSA2
Proteasome subunit alpha type-2

1

2

High-throughput

0.515

High

607595

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.515

High

607619

EPIPL
Epiplakin

1

2

High-throughput

0.515

High

607632

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.515

High

607646

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

1

High-throughput

0.515

High

607659

PDIA6
Protein disulfide-isomerase A6

1

3

High-throughput

0.515

High

607671

CP135
Centrosomal protein of 135 kDa

1

3

High-throughput

0.515

High

607738

RUVB2
RuvB-like 2

1

2

High-throughput

0.515

High

294197

DDAH1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

1

0

High-throughput

0.513

High

301471

WDR47
WD repeat-containing protein 47

1

0

High-throughput

0.513

High

351519

ANF
Natriuretic peptides A

1

0

High-throughput

0.513

High

607600

ACTN2
Alpha-actinin-2

1

0

High-throughput

0.513

High

607601

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

0

High-throughput

0.513

High

607603

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

607607

CSRP3
Cysteine and glycine-rich protein 3

1

0

High-throughput

0.513

High

607692

ZN843
Zinc finger protein 843

1

0

High-throughput

0.513

High

607694

FA24B
Protein FAM24B

1

0

High-throughput

0.513

High

607698

PPTC7
Protein phosphatase PTC7 homolog

1

0

High-throughput

0.513

High

607699

HMGC2
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic

1

0

High-throughput

0.513

High

607700

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

607711

IER2
Immediate early response gene 2 protein

1

0

High-throughput

0.513

High

607718

KDM4C
Lysine-specific demethylase 4C

1

0

High-throughput

0.513

High

607747

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

607713

KLF16
Krueppel-like factor 16

1

2

High-throughput

0.500

High

607594

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

High-throughput

0.493

High

607596

KINH
Kinesin-1 heavy chain

1

0

High-throughput

0.493

High

607613

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.493

High

607625

LYSC
Lysozyme C

1

0

High-throughput

0.493

High

607635

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.493

High

607653

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.493

High

607662

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.493

High

445247

CEL3B
Chymotrypsin-like elastase family member 3B

1

2

High-throughput

0.489

High

607693

ARG39
Rho guanine nucleotide exchange factor 39

1

2

High-throughput

0.489

High

607652

GIT2
ARF GTPase-activating protein GIT2

1

1

High-throughput

0.481

High

607658

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

3

Small-scale

0.481

High

607685

HERC6
Probable E3 ubiquitin-protein ligase HERC6

1

3

Small-scale

0.481

High

135367

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

1

High-throughput

0.479

High

165931

PER2
Period circadian protein homolog 2

1

1

Small-scale

0.479

High

199665

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.479

High

216172

CALU
Calumenin

1

4

High-throughput

0.479

High

236404

RNBP6
Ran-binding protein 6

1

2

High-throughput

0.479

High

323586

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.479

High

341575

CFAB
Complement factor B

1

4

High-throughput

0.479

High

373684

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

403086

LA
Lupus La protein

1

1

High-throughput

0.479

High

443329

VIME
Vimentin

1

2

Small-scale

0.479

High

488572

ARAF
Serine/threonine-protein kinase A-Raf

1

6

High-throughput

0.479

High

501678

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.479

High

503436

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

541962

OXDA
D-amino-acid oxidase

1

1

High-throughput

0.479

High

542817

BRAF
Serine/threonine-protein kinase B-raf

1

5

High-throughput

0.479

High

548638

VAV
Proto-oncogene vav

1

3

High-throughput

0.479

High

551948

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

556583

CBR1
Carbonyl reductase [NADPH] 1

1

3

High-throughput

0.479

High

569187

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

575269

EGR1
Early growth response protein 1

1

2

High-throughput

0.479

High

601124

VDAC1
Voltage-dependent anion-selective channel protein 1

1

2

High-throughput

0.479

High

607587

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

607589

EF1G
Elongation factor 1-gamma

1

3

High-throughput

0.479

High

607590

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

607591

PSB4
Proteasome subunit beta type-4

1

3

High-throughput

0.479

High

607593

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.479

High

607597

H2B1B
Histone H2B type 1-B

1

1

High-throughput

0.479

High

607604

EFTU
Elongation factor Tu, mitochondrial

1

3

High-throughput

0.479

High

607606

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

607608

F10A1
Hsc70-interacting protein

1

3

High-throughput

0.479

High

607610

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

607612

KS6A3
Ribosomal protein S6 kinase alpha-3

1

2

High-throughput

0.479

High

607615

RD23A
UV excision repair protein RAD23 homolog A

1

5

High-throughput

0.479

High

607618

HDAC4
Histone deacetylase 4

1

4

High-throughput

0.479

High

607621

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

1

High-throughput

0.479

High

607627

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.479

High

607628

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

607631

H4
Histone H4

1

1

High-throughput

0.479

High

607633

RAC1
Ras-related C3 botulinum toxin substrate 1

1

2

High-throughput

0.479

High

607634

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.479

High

607638

H33
Histone H3.3

1

1

High-throughput

0.479

High

607643

SET
Protein SET

1

2

High-throughput

0.479

High

607644

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

1

High-throughput

0.479

High

607645

SOS1
Son of sevenless homolog 1

1

4

High-throughput

0.479

High

607648

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

607656

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.479

High

607657

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

607660

KS6A2
Ribosomal protein S6 kinase alpha-2

1

2

High-throughput

0.479

High

607661

PCBP1
Poly(rC)-binding protein 1

1

1

High-throughput

0.479

High

607663

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

607665

RHG44
Rho GTPase-activating protein 44

1

3

High-throughput

0.479

High

607666

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

607667

RHG31
Rho GTPase-activating protein 31

1

4

High-throughput

0.479

High

607670

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.479

High

607675

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

607678

ASXL2
Putative Polycomb group protein ASXL2

1

5

High-throughput

0.479

High

607682

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

607683

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

607684

GOLI
E3 ubiquitin-protein ligase RNF130

1

3

High-throughput

0.479

High

607686

ASXL1
Polycomb group protein ASXL1

1

4

High-throughput

0.479

High

607687

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

607695

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.479

High

607697

PLBL2
Putative phospholipase B-like 2

1

1

High-throughput

0.479

High

607702

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

607704

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

607705

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

607706

ARHG1
Rho guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

607708

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

607709

RUFY1
RUN and FYVE domain-containing protein 1

1

2

High-throughput

0.479

High

607710

OVOL2
Transcription factor Ovo-like 2

1

1

Small-scale

0.479

High

607714

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.479

High

607715

ASXL3
Putative Polycomb group protein ASXL3

1

5

High-throughput

0.479

High

607717

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

1

High-throughput

0.479

High

607725

INO1
Inositol-3-phosphate synthase 1

1

1

High-throughput

0.479

High

607726

RTN4
Reticulon-4

1

2

High-throughput

0.479

High

607728

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

607731

Q9NZ23
Drug-sensitive protein 1

1

1

High-throughput

0.479

High

607734

HDAC6
Histone deacetylase 6

1

4

High-throughput

0.479

High

607735

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

607739

NINL
Ninein-like protein

1

4

High-throughput

0.479

High

607746

STRAP
Serine-threonine kinase receptor-associated protein

1

1

High-throughput

0.479

High

234069

O10H3
Olfactory receptor 10H3

1

2

High-throughput

0.470

High

607592

5HT1B
5-hydroxytryptamine receptor 1B

1

1

High-throughput

0.470

High

313752

SVIL
Supervillin

1

0

Small-scale

0.460

High

607680

BNIPL
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein

1

0

High-throughput

0.460

High

121931

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

High-throughput

0.458

High

123499

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.458

High

298154

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

353186

KVD28
Immunoglobulin kappa variable 2D-28

1

0

High-throughput

0.458

High

381800

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

607598

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

607602

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

607616

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.458

High

607620

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

607622

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

607624

MGN
Protein mago nashi homolog

1

0

High-throughput

0.458

High

607637

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

0

High-throughput

0.458

High

607649

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

0

Small-scale

0.458

High

607651

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

607655

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

607672

Q6FHQ0
Histone-binding protein RBBP7

1

0

High-throughput

0.458

High

607679

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.458

High

607681

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

607688

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

607691

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

0

High-throughput

0.458

High

607716

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

607724

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

607730

HYPK
Huntingtin-interacting protein K

1

0

Small-scale

0.458

High

607741

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.458

High

607744

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.458

High

607745

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

607629

RHOB
Rho-related GTP-binding protein RhoB

1

3

Small-scale

0.457

High

607677

TBA1A
Tubulin alpha-1A chain

1

5

High-throughput

0.445

High

607689

CDK20
Cyclin-dependent kinase 20

1

3

High-throughput

0.445

High

607740

AMOL2
Angiomotin-like protein 2

1

2

High-throughput

0.445

High

205045

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

607599

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

607654

RCN2
Reticulocalbin-2

1

5

High-throughput

0.437

High

607720

SMOC1
SPARC-related modular calcium-binding protein 1

1

1

High-throughput

0.437

High

607729

OCAD1
OCIA domain-containing protein 1

1

3

High-throughput

0.437

High

607733

MTCH1
Mitochondrial carrier homolog 1

1

3

High-throughput

0.437

High

607742

RT28
Small ribosomal subunit protein bS1m

1

1

High-throughput

0.437

High

607743

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

607639

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.426

High

607707

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

607605

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.408

High

600863

TA2R
Thromboxane A2 receptor

1

0

Small-scale

0.299

High

130437

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.279

Low

607703

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.279

Low

607737

PILRB
Paired immunoglobulin-like type 2 receptor beta

1

0

High-throughput

0.279

Low

390714

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

607669

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

607674

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

607676

CEFIP
Cardiac-enriched FHL2-interacting protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024