Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4
Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.60 | 1.00 | 0.776 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | LRR_4~PK_Tyr_Ser-Thr, LRR_4~SH3_1, LRR_8~PK_Tyr_Ser-Thr, LRR_8~SH2 |
Common GO terms | GO:0005102 - signaling receptor binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014911 - positive regulation of smooth muscle cell migration GO:0036120 - cellular response to platelet-derived growth factor stimulus and 4 others more... |
Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024