Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 20379791, 21911421
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_4~PK_Tyr_Ser-Thr, LRR_4~SH3_1, LRR_8~PK_Tyr_Ser-Thr, LRR_8~SH2
Common GO terms GO:0005102 - signaling receptor binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014911 - positive regulation of smooth muscle cell migration
GO:0036120 - cellular response to platelet-derived growth factor stimulus
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 839
Hs

1 536
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Last updated: 15 Jul 2024