Protein: Q9VVL7
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)

Gene: Q9VVL7, Dld
Organism: Drosophila melanogaster
Interactions: 192
UniProt ID: Q9VVL7

Gene Ontology (top 5):
GO:0004148 - dihydrolipoyl dehydrogenase (NADH) activity
GO:0005759 - mitochondrial matrix
GO:0005960 - glycine cleavage complex
GO:0006086 - pyruvate decarboxylation to acetyl-CoA
GO:0006099 - tricarboxylic acid cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1019686

TRXR1
Thioredoxin reductase 1, mitochondrial

2

15

High-throughput

0.726

High

1031293

PGK
Phosphoglycerate kinase

2

2

High-throughput

0.571

High

1480441

Q9VL70
HL08109p

2

1

High-throughput

0.571

High

357625

INO1
Inositol-3-phosphate synthase

2

1

High-throughput

0.521

High

477060

NDKA
Nucleoside diphosphate kinase

2

1

High-throughput

0.521

High

762660

UCHL
Ubiquitin carboxyl-terminal hydrolase

2

2

High-throughput

0.521

High

1375083

ATU
Another transcription unit protein

2

1

High-throughput

0.521

High

1486335

Q9VTY2
Uncharacterized protein, isoform A

2

9

High-throughput

0.521

High

929600

PDI
Protein disulfide-isomerase

1

8

High-throughput

0.514

High

1014752

CYC2
Cytochrome c-2

1

1

High-throughput

0.514

High

1191731

Q3YMU0
Protein disulfide-isomerase

1

6

High-throughput

0.514

High

1465079

THIO2
Thioredoxin-2

1

10

High-throughput

0.514

High

1465301

PDIA6
Protein disulfide-isomerase A6 homolog

1

7

High-throughput

0.514

High

1474372

Q9VG33
Sulfurtransferase

1

1

High-throughput

0.514

High

1487363

TXND5
Thioredoxin domain-containing protein 5 homolog

1

8

High-throughput

0.514

High

1487366

Q9W022
GEO01508p1

1

16

High-throughput

0.514

High

120129

M9PCG1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

1

16

High-throughput

0.479

High

641874

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

1

High-throughput

0.457

High

460194

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.445

High

1070837

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

3

High-throughput

0.445

High

1263088

Q7JXC4
CG6459 protein

1

1

High-throughput

0.445

High

1343077

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

1

High-throughput

0.445

High

1467678

Q9VAC1
GM14349p

1

1

High-throughput

0.445

High

1468227

Q9VAN7
Phosphoglycerate mutase

1

2

High-throughput

0.445

High

1472514

Q9VEB1
Malate dehydrogenase, mitochondrial

1

6

High-throughput

0.445

High

1472960

FLNA
Filamin-A

1

4

High-throughput

0.445

High

1474448

Q9VG69
LP03547p

1

2

High-throughput

0.445

High

1477411

Q9VIE8
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.445

High

1481392

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

16

High-throughput

0.445

High

1485639

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

3

High-throughput

0.445

High

1486474

Q9VU35
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.445

High

1487372

Q9W3X6
fumarate hydratase

1

1

High-throughput

0.445

High

1487374

CISY
Probable citrate synthase, mitochondrial

1

3

High-throughput

0.445

High

1487376

Q9W457
Serine hydroxymethyltransferase

1

2

High-throughput

0.445

High

56223

A1ZA03
Pms2

1

1

High-throughput

0.439

High

1304133

Q8INQ9
LIM domain-containing protein

1

2

High-throughput

0.439

High

654403

DDX6
ATP-dependent RNA helicase me31b

1

1

High-throughput

0.437

High

1061467

GRAP
Growth factor receptor-bound protein 2

1

1

High-throughput

0.437

High

714700

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.426

High

875185

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.426

High

1026677

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.426

High

1176829

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.426

High

303890

O76417
MutL homolog PMS2

1

1

High-throughput

0.417

High

1304165

Q8INR0
LIM domain-containing protein

1

2

High-throughput

0.417

High

1487266

MSIR6
RNA-binding protein Musashi homolog Rbp6

1

1

High-throughput

0.417

High

47815

A0AQH0
Proteasome subunit beta

1

2

High-throughput

0.407

High

54109

A1Z892
1-Cys peroxiredoxin

1

10

High-throughput

0.407

High

57668

A1ZB71
Glutathione S transferase E6

1

3

High-throughput

0.407

High

57889

A1ZB77
Uncharacterized protein, isoform J

1

2

High-throughput

0.407

High

86598

B9EQV3
Endoplasmic reticulum transmembrane protein

1

1

High-throughput

0.407

High

121347

ALDR
Aldo-keto reductase 1B

1

9

High-throughput

0.407

High

195151

O16043
Anon1A4

1

1

High-throughput

0.407

High

197889

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.407

High

234644

VINC
Vinculin

1

2

High-throughput

0.407

High

234803

O46067
Hypoxia up-regulated protein 1

1

5

High-throughput

0.407

High

304734

RS21
Small ribosomal subunit protein eS21

1

1

High-throughput

0.407

High

305282

TRMB
tRNA

1

1

High-throughput

0.407

High

305743

IPYR
Inorganic pyrophosphatase

1

2

High-throughput

0.407

High

356463

O97102
Small ubiquitin-related modifier

1

2

High-throughput

0.407

High

357395

O97428
Ciboulot, isoform A

1

1

High-throughput

0.407

High

556800

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.407

High

578175

ENO
Enolase

1

4

High-throughput

0.407

High

609498

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.407

High

611556

PSA4
Proteasome subunit alpha type-4

1

2

High-throughput

0.407

High

648973

ANXB9
Annexin B9

1

4

High-throughput

0.407

High

649137

ANX10
Annexin B10

1

4

High-throughput

0.407

High

682844

PROF
Profilin

1

3

High-throughput

0.407

High

712444

CALR
Calreticulin

1

1

High-throughput

0.407

High

821938

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.407

High

835226

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

1

High-throughput

0.407

High

856159

MOEH
Moesin/ezrin/radixin homolog 1

1

1

High-throughput

0.407

High

871715

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

7

High-throughput

0.407

High

874731

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

1

High-throughput

0.407

High

929082

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

2

High-throughput

0.407

High

930244

VATE
V-type proton ATPase subunit E

1

1

High-throughput

0.407

High

1052300

HMGD
High mobility group protein D

1

1

High-throughput

0.407

High

1052503

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.407

High

1069913

Q0E993
Valine--tRNA ligase

1

4

High-throughput

0.407

High

1176371

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

3

High-throughput

0.407

High

1176636

NLP
Nucleoplasmin-like protein

1

3

High-throughput

0.407

High

1260907

Q76NR6
Regucalcin

1

2

High-throughput

0.407

High

1262200

Q7JVH6
LD24696p

1

9

High-throughput

0.407

High

1262687

Q7JWV7
Tetraspanin

1

1

High-throughput

0.407

High

1262889

Q7JX87
1-Cys peroxiredoxin

1

10

High-throughput

0.407

High

1264171

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.407

High

1264749

Q7K148
Proteasome subunit beta

1

2

High-throughput

0.407

High

1265333

Q7K2K2
FI04612p

1

1

High-throughput

0.407

High

1267994

TERA
Transitional endoplasmic reticulum ATPase TER94

1

5

High-throughput

0.407

High

1268304

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

1

High-throughput

0.407

High

1269343

Q7KTJ7
Basigin, isoform G

1

1

High-throughput

0.407

High

1269518

Q7KTW5
Inositol-1-monophosphatase

1

2

High-throughput

0.407

High

1303994

Q8INK3
Fatty acid-binding protein, muscle

1

1

High-throughput

0.407

High

1305794

Q8IQZ7
FI19014p1

1

6

High-throughput

0.407

High

1306188

Q8IRD3
Glutathione peroxidase

1

1

High-throughput

0.407

High

1321748

Q8MT58
Carnosine dipeptidase 2, isoform A

1

1

High-throughput

0.407

High

1322008

Q8MYY7
RE44624p

1

3

High-throughput

0.407

High

1343371

OLA1
Obg-like ATPase 1

1

2

High-throughput

0.407

High

1345317

Q8T0L3
E1 ubiquitin-activating enzyme

1

2

High-throughput

0.407

High

1374616

NACA
Nascent polypeptide-associated complex subunit alpha

1

2

High-throughput

0.407

High

1374735

ACPM
Acyl carrier protein, mitochondrial

1

3

High-throughput

0.407

High

1377720

FAXC
Failed axon connections

1

2

High-throughput

0.407

High

1427906

IF5A
Eukaryotic translation initiation factor 5A

1

1

High-throughput

0.407

High

1440089

JUPIT
Microtubule-associated protein Jupiter

1

1

High-throughput

0.407

High

1440206

NASP
Nuclear autoantigenic sperm protein homolog

1

1

High-throughput

0.407

High

1440629

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

2

High-throughput

0.407

High

1445475

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

1

High-throughput

0.407

High

1463714

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

1

High-throughput

0.407

High

1464378

Q9V3V2
peptidylprolyl isomerase

1

7

High-throughput

0.407

High

1464630

Q9V3V9
Endonuclease G inhibitor, isoform A

1

1

High-throughput

0.407

High

1466104

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.407

High

1467018

Q9V9U3
LD45254p

1

1

High-throughput

0.407

High

1467771

Q9VAC4
GEO09167p1

1

3

High-throughput

0.407

High

1468685

Q9VAY2
Heat shock protein 83

1

4

High-throughput

0.407

High

1469548

Q9VBR6
RE74917p

1

1

High-throughput

0.407

High

1470546

Q9VCK6
LD34157p

1

1

High-throughput

0.407

High

1471011

Q9VD02
GH14779p

1

3

High-throughput

0.407

High

1471177

Q9VD29
small monomeric GTPase

1

5

High-throughput

0.407

High

1474791

Q9VGK3
peptidylprolyl isomerase

1

7

High-throughput

0.407

High

1475151

TCTP
Translationally-controlled tumor protein homolog

1

1

High-throughput

0.407

High

1475770

Q9VH81
protein-serine/threonine phosphatase

1

4

High-throughput

0.407

High

1475972

TEBPH
Cytosolic Prostaglandin E synthase

1

2

High-throughput

0.407

High

1476498

Q9VHN7
transketolase

1

4

High-throughput

0.407

High

1476898

Q9VHX4
LD24679p

1

9

High-throughput

0.407

High

1477003

Q9VI04
Beta-ureidopropionase

1

1

High-throughput

0.407

High

1478506

Q9VJJ0
Proteasome subunit beta

1

4

High-throughput

0.407

High

1479239

Q9VK60
GH25425p

1

3

High-throughput

0.407

High

1479327

Q9VKB0
threonine--tRNA ligase

1

3

High-throughput

0.407

High

1479937

Q9VKW5
Prolyl endopeptidase

1

1

High-throughput

0.407

High

1480097

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

2

High-throughput

0.407

High

1480192

EF1D
Probable elongation factor 1-delta

1

3

High-throughput

0.407

High

1480376

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

4

High-throughput

0.407

High

1480518

FKB59
FK506-binding protein 59

1

5

High-throughput

0.407

High

1480553

Q9VL89
Methionine aminopeptidase 2

1

2

High-throughput

0.407

High

1480644

Q9VLB7
Rab GDP dissociation inhibitor

1

1

High-throughput

0.407

High

1480852

AK200
A-kinase anchor protein 200

1

4

High-throughput

0.407

High

1480917

SYAC
Alanine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.407

High

1481123

Q9VLS7
LD21067p

1

1

High-throughput

0.407

High

1482008

Q9VMU6
LD31822p

1

1

High-throughput

0.407

High

1482470

PSB4
Proteasome subunit beta type-4

1

6

High-throughput

0.407

High

1482513

Q9VNB2
RE42193p

1

1

High-throughput

0.407

High

1483403

Q9VPN5
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.407

High

1483699

Q9VPX6
Adenylyl cyclase-associated protein

1

2

High-throughput

0.407

High

1484142

BACC
Bacchus

1

1

High-throughput

0.407

High

1484322

Q9VQL1
serine--tRNA ligase

1

4

High-throughput

0.407

High

1484357

Q9VQL7
Fatty acid synthase

1

3

High-throughput

0.407

High

1484833

Q9VRD6
NTF2-related export protein

1

2

High-throughput

0.407

High

1484966

Q9VRL1
GEO06356p1

1

1

High-throughput

0.407

High

1485045

Q9VRP2
Uncharacterized protein, isoform A

1

2

High-throughput

0.407

High

1485682

Q9VSL2
Glutathione S transferase O3

1

3

High-throughput

0.407

High

1486549

WDR1
Actin-interacting protein 1

1

1

High-throughput

0.407

High

1486621

Q9VUC1
Hsc70Cb, isoform A

1

7

High-throughput

0.407

High

1487186

Y9705
Cold shock domain-containing protein CG9705

1

1

High-throughput

0.407

High

1487358

Q9VW59
Rho GDP-dissociation inhibitor 3

1

1

High-throughput

0.407

High

1487359

RS10B
Small ribosomal subunit protein eS10B

1

1

High-throughput

0.407

High

1487360

Q9VWQ7
Coactosin-like protein

1

1

High-throughput

0.407

High

1487361

DHB4
Peroxisomal multifunctional enzyme type 2

1

2

High-throughput

0.407

High

1487362

CLIC
Chloride intracellular channel Clic

1

3

High-throughput

0.407

High

1487364

Q9VZI1
Transgelin

1

2

High-throughput

0.407

High

1487365

Q9VZY0
LD45195p

1

1

High-throughput

0.407

High

1487367

Q9W0H8
Reticulocalbin-3

1

1

High-throughput

0.407

High

1487368

SND1
Staphylococcal nuclease domain-containing protein 1

1

2

High-throughput

0.407

High

1487369

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.407

High

1487373

Q9W3Y3
Calcyclin-binding protein

1

3

High-throughput

0.407

High

1487375

WUHO
tRNA

1

2

High-throughput

0.407

High

1487377

Q9W478
RE43153p

1

1

High-throughput

0.407

High

1487378

PSB3
Proteasome subunit beta type-3

1

4

High-throughput

0.407

High

1487379

Q9XYZ9
Glutathione S transferase E12, isoform A

1

3

High-throughput

0.407

High

1487380

Q9XZ57
Eb1, isoform E

1

1

High-throughput

0.407

High

1487381

PSA6
Proteasome subunit alpha type-6

1

5

High-throughput

0.407

High

1487382

PURA
Adenylosuccinate synthetase

1

1

High-throughput

0.407

High

1487383

Q9Y112
BcDNA.GH10614

1

9

High-throughput

0.407

High

1473713

Q9VFB9
GH09339p

1

0

High-throughput

0.265

Low

1377510

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

146006

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.232

Low

197537

SPS1
Inactive selenide, water dikinase-like protein

1

0

High-throughput

0.232

Low

356595

O97121
cystathionine gamma-lyase

1

0

High-throughput

0.232

Low

426827

HP1
Heterochromatin protein 1

1

0

High-throughput

0.232

Low

633015

GLNA1
Glutamine synthetase 1, mitochondrial

1

0

High-throughput

0.232

Low

1175393

NETB
Netrin-B

1

0

High-throughput

0.232

Low

1176762

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.232

Low

1268122

Q7KN85
ATP-citrate synthase

1

0

High-throughput

0.232

Low

1344478

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.232

Low

1409512

Q9BN17
Echinoid

1

0

High-throughput

0.232

Low

1463350

Q9V3D8
GH27579p

1

0

High-throughput

0.232

Low

1466289

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.232

Low

1473828

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

0

High-throughput

0.232

Low

1474322

Q9VG31
Malic enzyme

1

0

High-throughput

0.232

Low

1476643

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.232

Low

1482185

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.232

Low

1483830

Q9VQ61
Aspartate aminotransferase

1

0

High-throughput

0.232

Low

1487370

Q9W2M4
Farnesoic acid O-methyl transferase domain-containing protein

1

0

High-throughput

0.232

Low

1487371

Q9W3F6
Bleomycin hydrolase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025