Protein: PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (PEPCK-C) (EC 4.1.1.32) (Serine-protein kinase PCK1) (EC 2.7.11.-)

Gene: PCKGC, PCK1
Organism: Homo sapiens
Interactions: 108
UniProt ID: P35558

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004613 - phosphoenolpyruvate carboxykinase (GTP) activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

724439

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

2

0

High-throughput

0.770

High

304047

UBR5
E3 ubiquitin-protein ligase UBR5

3

0

Small-scale

0.623

High

724433

EP300
Histone acetyltransferase p300

2

1

Small-scale

0.584

High

181068

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.578

High

724475

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.578

High

724478

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.537

High

681694

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.536

High

724443

NHLC1
E3 ubiquitin-protein ligase NHLRC1

1

1

High-throughput

0.536

High

724450

CUL5
Cullin-5

1

1

High-throughput

0.536

High

724470

ZMYM2
Zinc finger MYM-type protein 2

1

4

High-throughput

0.536

High

245478

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.513

High

270183

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.513

High

451851

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.513

High

657870

CYTD
Cystatin-D

1

0

High-throughput

0.513

High

685627

PRDX2
Peroxiredoxin-2

1

0

High-throughput

0.513

High

724435

DNJC3
DnaJ homolog subfamily C member 3

1

0

High-throughput

0.513

High

724459

CIB3
Calcium and integrin-binding family member 3

1

0

High-throughput

0.513

High

724463

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

0

High-throughput

0.513

High

724464

DUS15
Dual specificity protein phosphatase 15

1

0

High-throughput

0.513

High

724466

VPP4
V-type proton ATPase 116 kDa subunit a 4

1

0

High-throughput

0.513

High

724473

AR2BP
ADP-ribosylation factor-like protein 2-binding protein

1

0

High-throughput

0.513

High

394220

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

146601

SOCS2
Suppressor of cytokine signaling 2

1

0

High-throughput

0.493

High

724462

MAD3
Max dimerization protein 3

1

1

High-throughput

0.489

High

724448

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

499576

CH60
60 kDa heat shock protein, mitochondrial

1

1

Small-scale

0.479

High

573150

TCPA
T-complex protein 1 subunit alpha

1

1

Small-scale

0.479

High

594463

PSB1
Proteasome subunit beta type-1

1

1

Small-scale

0.479

High

611383

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

3

Small-scale

0.479

High

637638

PSA2
Proteasome subunit alpha type-2

1

1

Small-scale

0.479

High

656157

PSA5
Proteasome subunit alpha type-5

1

1

Small-scale

0.479

High

656421

PSB4
Proteasome subunit beta type-4

1

4

Small-scale

0.479

High

724407

PRS7
26S proteasome regulatory subunit 7

1

2

Small-scale

0.479

High

724409

NUP62
Nuclear pore glycoprotein p62

1

1

Small-scale

0.479

High

724410

HNF4A
Hepatocyte nuclear factor 4-alpha

1

2

Small-scale

0.479

High

724411

PRS6B
26S proteasome regulatory subunit 6B

1

2

Small-scale

0.479

High

724413

TCPE
T-complex protein 1 subunit epsilon

1

2

Small-scale

0.479

High

724417

TCPD
T-complex protein 1 subunit delta

1

1

Small-scale

0.479

High

724418

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

Small-scale

0.479

High

724421

PRS4
26S proteasome regulatory subunit 4

1

2

Small-scale

0.479

High

724422

PRS8
26S proteasome regulatory subunit 8

1

3

Small-scale

0.479

High

724426

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

1

Small-scale

0.479

High

724427

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

1

Small-scale

0.479

High

724430

TCPB
T-complex protein 1 subunit beta

1

2

Small-scale

0.479

High

724431

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

1

Small-scale

0.479

High

724446

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

1

Small-scale

0.479

High

724460

PSB7
Proteasome subunit beta type-7

1

1

Small-scale

0.479

High

724465

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

1

Small-scale

0.479

High

724468

DDX21
Nucleolar RNA helicase 2

1

1

Small-scale

0.479

High

724472

MAGD2
Melanoma-associated antigen D2

1

1

Small-scale

0.479

High

724476

MAGD1
Melanoma-associated antigen D1

1

1

Small-scale

0.479

High

724471

ZMYM5
Zinc finger MYM-type protein 5

1

4

High-throughput

0.470

High

341159

C1R
Complement C1r subcomponent

1

0

High-throughput

0.460

High

121951

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

Small-scale

0.458

High

130769

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

Small-scale

0.458

High

133902

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.458

High

151727

IRS4
Insulin receptor substrate 4

1

0

Small-scale

0.458

High

334148

LDHA
L-lactate dehydrogenase A chain

1

0

Small-scale

0.458

High

400767

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.458

High

475415

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

488143

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

Small-scale

0.458

High

616148

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

646679

1433T
14-3-3 protein theta

1

0

Small-scale

0.458

High

681347

DNJA1
DnaJ homolog subfamily A member 1

1

0

Small-scale

0.458

High

713914

HS71L
Heat shock 70 kDa protein 1-like

1

0

Small-scale

0.458

High

724406

BASI
Basigin

1

0

Small-scale

0.458

High

724408

RL4
Large ribosomal subunit protein uL4

1

0

Small-scale

0.458

High

724412

BAG6
Large proline-rich protein BAG6

1

0

Small-scale

0.458

High

724414

FAS
Fatty acid synthase

1

0

Small-scale

0.458

High

724415

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

Small-scale

0.458

High

724416

RL14
Large ribosomal subunit protein eL14

1

0

Small-scale

0.458

High

724419

ACTB
Actin, cytoplasmic 1

1

0

Small-scale

0.458

High

724420

RS3A
Small ribosomal subunit protein eS1

1

0

Small-scale

0.458

High

724423

RS15A
Small ribosomal subunit protein uS8

1

0

Small-scale

0.458

High

724424

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.458

High

724425

RL23
Large ribosomal subunit protein uL14

1

0

Small-scale

0.458

High

724428

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

724429

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.458

High

724432

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.458

High

724434

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

Small-scale

0.458

High

724436

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

724437

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

Small-scale

0.458

High

724438

ELOC
Elongin-C

1

0

Small-scale

0.458

High

724444

GGYF2
GRB10-interacting GYF protein 2

1

0

Small-scale

0.458

High

724447

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

0

Small-scale

0.458

High

724454

FAF2
FAS-associated factor 2

1

0

Small-scale

0.458

High

724458

RL10L
Ribosomal protein uL16-like

1

0

Small-scale

0.458

High

724461

T22D3
TSC22 domain family protein 3

1

0

Small-scale

0.458

High

724467

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

Small-scale

0.458

High

724474

SRPRB
Signal recognition particle receptor subunit beta

1

0

Small-scale

0.458

High

168345

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.279

Low

215837

ANGL7
Angiopoietin-related protein 7

1

0

High-throughput

0.279

Low

351145

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.279

Low

724441

SPAT1
Spermatogenesis-associated protein 1

1

0

High-throughput

0.279

Low

724442

ACKMT
ATP synthase subunit C lysine N-methyltransferase

1

0

High-throughput

0.279

Low

724445

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.279

Low

724449

DCNL4
DCN1-like protein 4

1

0

High-throughput

0.279

Low

724451

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

724452

ZDH16
Palmitoyltransferase ZDHHC16

1

0

High-throughput

0.279

Low

724453

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.279

Low

724455

ZN501
Zinc finger protein 501

1

0

High-throughput

0.279

Low

724456

MITOK
Mitochondrial potassium channel

1

0

High-throughput

0.279

Low

724457

MYEOV
Myeloma-overexpressed gene protein

1

0

High-throughput

0.279

Low

724469

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.279

Low

724477

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.279

Low

724440

Z585B
Zinc finger protein 585B

1

0

High-throughput

0.269

Low

163759

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

Small-scale

0.249

Low

252807

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024