Protein: PCGF2
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)

Gene: PCGF2
Organism: Homo sapiens
Interactions: 91
UniProt ID: P35227

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0001701 - in utero embryonic development
GO:0001739 - sex chromatin
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

718420

RING2
E3 ubiquitin-protein ligase RING2

16

19

Small-scale

0.988

High

718393

RING1
E3 ubiquitin-protein ligase RING1

12

19

Small-scale

0.983

High

718431

CBX8
Chromobox protein homolog 8

10

20

Small-scale

0.980

High

718398

CBX2
Chromobox protein homolog 2

9

20

Small-scale

0.972

High

123194

CBX4
E3 SUMO-protein ligase CBX4

9

20

Small-scale

0.970

High

327831

CBX7
Chromobox protein homolog 7

6

20

Small-scale

0.957

High

718410

RYBP
RING1 and YY1-binding protein

6

20

High-throughput

0.950

High

718409

YAF2
YY1-associated factor 2

6

20

Small-scale

0.945

High

315977

CBX6
Chromobox protein homolog 6

5

20

High-throughput

0.929

High

717489

BMI1
Polycomb complex protein BMI-1

4

20

Small-scale

0.892

High

718403

BCORL
BCL-6 corepressor-like protein 1

3

20

High-throughput

0.861

High

718387

UBC9
SUMO-conjugating enzyme UBC9

3

20

Small-scale

0.857

High

718376

PCGF2
Polycomb group RING finger protein 2

2

19

Small-scale

0.768

High

718390

PHC1
Polyhomeotic-like protein 1

11

20

Small-scale

0.758

High

718408

PHC2
Polyhomeotic-like protein 2

10

20

Small-scale

0.758

High

718405

BCOR
BCL-6 corepressor

2

20

High-throughput

0.754

High

718412

PHC3
Polyhomeotic-like protein 3

7

20

Small-scale

0.747

High

718418

SCMH1
Polycomb protein SCMH1

4

20

High-throughput

0.699

High

718419

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

20

High-throughput

0.698

High

718434

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

20

High-throughput

0.698

High

475406

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

Small-scale

0.691

High

718401

H2B2E
Histone H2B type 2-E

1

16

High-throughput

0.691

High

718414

UB2Q2
Ubiquitin-conjugating enzyme E2 Q2

1

0

High-throughput

0.663

High

718384

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

681691

AKT1
RAC-alpha serine/threonine-protein kinase

2

2

Small-scale

0.629

High

718417

LTV1
Protein LTV1 homolog

2

1

High-throughput

0.628

High

718404

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.625

High

718402

PCGF3
Polycomb group RING finger protein 3

1

19

High-throughput

0.618

High

718406

PCGF5
Polycomb group RING finger protein 5

1

19

High-throughput

0.618

High

718422

PCGF1
Polycomb group RING finger protein 1

1

19

High-throughput

0.618

High

718424

PCGF6
Polycomb group RING finger protein 6

1

19

High-throughput

0.618

High

718440

SCML1
Sex comb on midleg-like protein 1

2

20

High-throughput

0.611

High

718394

TRAF2
TNF receptor-associated factor 2

2

19

High-throughput

0.606

High

718397

NUCG
Endonuclease G, mitochondrial

2

0

High-throughput

0.602

High

718436

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

2

0

High-throughput

0.602

High

718382

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

20

Small-scale

0.597

High

718415

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

13

Small-scale

0.597

High

673027

CCND2
G1/S-specific cyclin-D2

1

2

Small-scale

0.589

High

265611

E2F6
Transcription factor E2F6

2

20

Small-scale

0.584

High

718426

KLH25
Kelch-like protein 25

2

1

High-throughput

0.574

High

718433

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

9

High-throughput

0.574

High

718392

HSF2
Heat shock factor protein 2

1

1

Small-scale

0.573

High

699247

STX2
Syntaxin-2

2

1

High-throughput

0.553

High

359706

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

19

Small-scale

0.552

High

309243

SPDEF
SAM pointed domain-containing Ets transcription factor

1

12

High-throughput

0.541

High

678989

HXC9
Homeobox protein Hox-C9

1

4

High-throughput

0.541

High

718383

SUMO3
Small ubiquitin-related modifier 3

1

4

High-throughput

0.541

High

718425

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

5

High-throughput

0.541

High

718400

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.536

High

718421

TBA1C
Tubulin alpha-1C chain

1

13

High-throughput

0.536

High

718432

MOV10
Helicase MOV-10

1

7

Small-scale

0.536

High

718435

LANC2
LanC-like protein 2

1

1

High-throughput

0.536

High

718441

NFS1
Cysteine desulfurase

1

1

High-throughput

0.536

High

718377

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.513

High

174668

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

7

High-throughput

0.501

High

312708

CXB5
Gap junction beta-5 protein

1

1

High-throughput

0.494

High

279453

FLOT1
Flotillin-1

1

4

High-throughput

0.489

High

434352

TPM2
Tropomyosin beta chain

1

6

High-throughput

0.489

High

718380

GBG10

1

1

High-throughput

0.489

High

718396

MSLN
Mesothelin

1

1

High-throughput

0.489

High

718411

KCD17
BTB/POZ domain-containing protein KCTD17

1

5

High-throughput

0.489

High

718438

FBLN5
Fibulin-5

1

3

High-throughput

0.489

High

244018

BRD4
Bromodomain-containing protein 4

1

10

High-throughput

0.479

High

267918

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

455144

PARP1
Poly [ADP-ribose] polymerase 1

1

15

High-throughput

0.479

High

586592

CSK22
Casein kinase II subunit alpha'

1

20

High-throughput

0.479

High

595115

LMNB1
Lamin-B1

1

20

Small-scale

0.479

High

632620

TYY1
Transcriptional repressor protein YY1

1

20

Small-scale

0.479

High

718378

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

Small-scale

0.479

High

718379

RAGP1
Ran GTPase-activating protein 1

1

4

Small-scale

0.479

High

718381

EMD
Emerin

1

2

Small-scale

0.479

High

718385

DCAF7
DDB1- and CUL4-associated factor 7

1

20

High-throughput

0.479

High

718386

SKP1
S-phase kinase-associated protein 1

1

10

High-throughput

0.479

High

718388

CSK2B
Casein kinase II subunit beta

1

9

High-throughput

0.479

High

718389

CSK21
Casein kinase II subunit alpha

1

20

High-throughput

0.479

High

718391

HSF1
Heat shock factor protein 1

1

1

Small-scale

0.479

High

718395

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

718399

PCBP1
Poly(rC)-binding protein 1

1

16

Small-scale

0.479

High

718407

MGAP
MAX gene-associated protein

1

12

High-throughput

0.479

High

718413

KDM2B
Lysine-specific demethylase 2B

1

20

High-throughput

0.479

High

718416

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

20

High-throughput

0.479

High

718428

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.479

High

718439

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

351136

EGF
Pro-epidermal growth factor

1

3

Small-scale

0.437

High

718429

FBRS
Probable fibrosin-1

1

20

High-throughput

0.437

High

718430

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

2

0

High-throughput

0.316

High

596507

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.282

High

718423

ABHD6
Monoacylglycerol lipase ABHD6

1

0

High-throughput

0.282

High

718437

CTNL1
Alpha-catulin

1

0

High-throughput

0.282

High

718427

CPVL
Probable serine carboxypeptidase CPVL

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024