Protein: TGM3
Protein-glutamine gamma-glutamyltransferase E (EC 2.3.2.13) (Transglutaminase E) (TG(E)) (TGE) (TGase E) (Transglutaminase-3) (TGase-3) [Cleaved into: Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain]

Gene: TGM3
Organism: Homo sapiens
Interactions: 154
UniProt ID: Q08188

Gene Ontology (top 5):
GO:0003810 - protein-glutamine gamma-glutamyltransferase activity
GO:0003824 - catalytic activity
GO:0005198 - structural molecule activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

365187

FRIH
Ferritin heavy chain

2

2

High-throughput

0.628

High

993995

MITOK
Mitochondrial potassium channel

3

2

High-throughput

0.609

High

386606

P53
Cellular tumor antigen p53

2

2

Small-scale

0.584

High

265637

E2F6
Transcription factor E2F6

2

1

High-throughput

0.574

High

994015

TB22B
TBC1 domain family member 22B

2

2

High-throughput

0.574

High

488694

ARAF
Serine/threonine-protein kinase A-Raf

2

2

High-throughput

0.571

High

993978

DOCK8
Dedicator of cytokinesis protein 8

2

2

High-throughput

0.571

High

883410

CF298
Cilia- and flagella-associated protein 298

2

1

High-throughput

0.558

High

993984

ARH40
Rho guanine nucleotide exchange factor 40

2

0

High-throughput

0.547

High

274995

RENR
Renin receptor

1

2

High-throughput

0.536

High

281986

ANXA9
Annexin A9

1

2

High-throughput

0.536

High

529030

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

565917

AATC
Aspartate aminotransferase, cytoplasmic

1

2

High-throughput

0.536

High

676738

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

2

High-throughput

0.536

High

686648

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

808105

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

High-throughput

0.536

High

993954

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.536

High

993965

APTX
Aprataxin

1

1

High-throughput

0.536

High

993973

CC103
Coiled-coil domain-containing protein 103

1

1

High-throughput

0.536

High

993976

PLD5
Inactive phospholipase D5

1

1

High-throughput

0.536

High

993980

MYBPP
MYCBP-associated protein

1

1

High-throughput

0.536

High

993996

MTNB
Methylthioribulose-1-phosphate dehydratase

1

1

High-throughput

0.536

High

993998

CDK15
Cyclin-dependent kinase 15

1

1

High-throughput

0.536

High

994005

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.536

High

994013

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

994033

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.536

High

994034

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

1

High-throughput

0.536

High

993974

SLX4
Structure-specific endonuclease subunit SLX4

2

3

High-throughput

0.521

High

812998

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

994037

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

1

Small-scale

0.501

High

993953

RHEB
GTP-binding protein Rheb

1

0

High-throughput

0.493

High

174384

FANCG
Fanconi anemia group G protein

1

1

High-throughput

0.489

High

333634

ADH1G
Alcohol dehydrogenase 1C

1

1

High-throughput

0.489

High

392928

IFNA4
Interferon alpha-4

1

1

High-throughput

0.489

High

624426

CCNC
Cyclin-C

1

1

High-throughput

0.489

High

708217

ERD22
ER lumen protein-retaining receptor 2

1

1

High-throughput

0.489

High

821552

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

840629

ASCL1
Achaete-scute homolog 1

1

1

High-throughput

0.489

High

882723

STX17
Syntaxin-17

1

2

High-throughput

0.489

High

958665

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.489

High

993955

CR021
UPF0711 protein C18orf21

1

1

High-throughput

0.489

High

993963

AMTN
Amelotin

1

1

High-throughput

0.489

High

993968

MOGT3
2-acylglycerol O-acyltransferase 3

1

1

High-throughput

0.489

High

993970

ZC3C1
Zinc finger C3HC-type protein 1

1

2

High-throughput

0.489

High

993971

AROS
Active regulator of SIRT1

1

1

High-throughput

0.489

High

993977

FNDC5
Fibronectin type III domain-containing protein 5

1

4

High-throughput

0.489

High

993981

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

1

High-throughput

0.489

High

993982

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.489

High

993988

THAP4
Peroxynitrite isomerase THAP4

1

4

High-throughput

0.489

High

993992

PIGT
GPI transamidase component PIG-T

1

1

High-throughput

0.489

High

993994

SARAF
Store-operated calcium entry-associated regulatory factor

1

1

High-throughput

0.489

High

994001

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.489

High

994003

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.489

High

994009

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

1

High-throughput

0.489

High

994011

TSSP
Thymus-specific serine protease

1

2

High-throughput

0.489

High

994020

THA10
THAP domain-containing protein 10

1

1

High-throughput

0.489

High

994026

PHF11
PHD finger protein 11

1

1

High-throughput

0.489

High

125407

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

Small-scale

0.479

High

133997

DDX3X
ATP-dependent RNA helicase DDX3X

1

1

Small-scale

0.479

High

227268

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

301784

TRI37
E3 ubiquitin-protein ligase TRIM37

1

2

High-throughput

0.479

High

346619

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

384715

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

427535

ANXA2
Annexin A2

1

2

High-throughput

0.479

High

503963

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

551680

DESP
Desmoplakin

1

1

High-throughput

0.479

High

596270

FILA
Filaggrin

1

5

High-throughput

0.479

High

683070

CASPE
Caspase-14

1

2

High-throughput

0.479

High

779297

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

832401

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

970759

DSG1
Desmoglein-1

1

2

High-throughput

0.479

High

993940

DSC1
Desmocollin-1

1

1

High-throughput

0.479

High

993943

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

2

High-throughput

0.479

High

993944

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

993946

PKP1
Plakophilin-1

1

1

High-throughput

0.479

High

993947

DX39B
Spliceosome RNA helicase DDX39B

1

3

High-throughput

0.479

High

993958

FILA2
Filaggrin-2

1

6

High-throughput

0.479

High

993972

PRAG1
Inactive tyrosine-protein kinase PRAG1

1

1

High-throughput

0.479

High

993990

RBP56
TATA-binding protein-associated factor 2N

1

6

High-throughput

0.479

High

993991

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

994000

RANB9
Ran-binding protein 9

1

2

Small-scale

0.479

High

994004

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

994017

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

994019

PD1L1
Programmed cell death 1 ligand 1

1

1

High-throughput

0.479

High

994024

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

994030

FBW1A
F-box/WD repeat-containing protein 1A

1

3

High-throughput

0.479

High

994035

LOXL2
Lysyl oxidase homolog 2

1

3

High-throughput

0.479

High

449698

HMGB1
High mobility group protein B1

1

3

Small-scale

0.464

High

134468

PODXL
Podocalyxin

1

0

Small-scale

0.458

High

258593

GGCT
Gamma-glutamylcyclotransferase

1

0

High-throughput

0.458

High

296716

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.458

High

303191

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

396228

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

719461

MERL
Merlin

1

0

High-throughput

0.458

High

993945

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

993948

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.458

High

993960

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.458

High

993987

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.458

High

993997

SPB12
Serpin B12

1

0

High-throughput

0.458

High

994014

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

994022

HDAC6
Histone deacetylase 6

1

0

Small-scale

0.458

High

994025

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

994032

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

0

Small-scale

0.458

High

853867

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.445

High

891108

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

3

High-throughput

0.445

High

988839

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.445

High

993941

STK4
Serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

993957

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

993959

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

282635

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.437

High

708613

MCM5
DNA replication licensing factor MCM5

1

3

High-throughput

0.437

High

908436

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

993950

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

1

1

High-throughput

0.437

High

993951

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.437

High

993952

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

993962

RICTR
Rapamycin-insensitive companion of mTOR

1

2

High-throughput

0.437

High

993966

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.437

High

993983

TP4AP
Short transient receptor potential channel 4-associated protein

1

1

High-throughput

0.437

High

993993

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

2

Small-scale

0.437

High

994006

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.437

High

994008

RNF38
E3 ubiquitin-protein ligase RNF38

1

1

Small-scale

0.437

High

994010

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.437

High

994012

ANLN
Anillin

1

1

High-throughput

0.437

High

994016

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

994023

DUX4
Double homeobox protein 4

1

1

High-throughput

0.437

High

994031

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

3

Small-scale

0.437

High

200547

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.426

High

993942

IFT88
Intraflagellar transport protein 88 homolog

1

2

High-throughput

0.407

High

994007

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.407

High

994002

PHAF1
Phagosome assembly factor 1

3

0

High-throughput

0.347

High

994027

FBXL4
F-box/LRR-repeat protein 4

2

0

High-throughput

0.328

High

994036

PPME1
Protein phosphatase methylesterase 1

2

0

High-throughput

0.319

High

878587

ALR
FAD-linked sulfhydryl oxidase ALR

1

0

High-throughput

0.279

Low

921110

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.279

Low

969013

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

0

High-throughput

0.279

Low

993949

I5P1
Inositol polyphosphate-5-phosphatase A

1

0

High-throughput

0.279

Low

993956

VWA3B
von Willebrand factor A domain-containing protein 3B

1

0

High-throughput

0.279

Low

993969

BPHL
Valacyclovir hydrolase

1

0

High-throughput

0.279

Low

993975

ORML3
ORM1-like protein 3

1

0

High-throughput

0.279

Low

993979

TYMOS
TYMS opposite strand protein

1

0

High-throughput

0.279

Low

993985

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

High-throughput

0.279

Low

993986

ZDH19
Palmitoyltransferase ZDHHC19

1

0

High-throughput

0.279

Low

994018

ZN224
Zinc finger protein 224

1

0

High-throughput

0.279

Low

994021

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.279

Low

994028

COR1C
Coronin-1C

1

0

High-throughput

0.279

Low

994029

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.279

Low

993964

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

0

High-throughput

0.269

Low

836824

DNLI4
DNA ligase 4

1

0

High-throughput

0.249

Low

993961

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

993967

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low

993989

RND1
Rho-related GTP-binding protein Rho6

1

0

High-throughput

0.249

Low

993999

GSDMA
Gasdermin-A

1

0

High-throughput

0.249

Low

994038

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.249

Low

789267

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024