Protein: WRIP1
ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1)

Gene: WRIP1, WRNIP1
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q96S55

Gene Ontology (top 5):
GO:0000731 - DNA synthesis involved in DNA repair
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006261 - DNA-templated DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476243

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

5

Small-scale

0.927

High

228436

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.754

High

1301733

WRIP1
ATPase WRNIP1

1

19

Small-scale

0.690

High

517418

PCNA
Proliferating cell nuclear antigen

1

15

Small-scale

0.647

High

360313

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

2

High-throughput

0.640

High

321927

RIGI
Antiviral innate immune response receptor RIG-I

2

3

High-throughput

0.639

High

875243

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.618

High

658416

DPOD1
DNA polymerase delta catalytic subunit

2

1

Small-scale

0.611

High

779953

CCNF
Cyclin-F

2

3

High-throughput

0.601

High

347657

MYC
Myc proto-oncogene protein

2

5

High-throughput

0.584

High

455778

PARP1
Poly [ADP-ribose] polymerase 1

2

13

High-throughput

0.584

High

1301747

RAD18
E3 ubiquitin-protein ligase RAD18

2

1

Small-scale

0.584

High

1301749

MCM9
DNA helicase MCM9

2

5

Small-scale

0.584

High

601983

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

9

High-throughput

0.576

High

1050619

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

6

Small-scale

0.573

High

1301741

TOLIP
Toll-interacting protein

1

0

High-throughput

0.561

High

1049122

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.552

High

301155

KDM4B
Lysine-specific demethylase 4B

1

9

High-throughput

0.536

High

878003

FOXA3
Hepatocyte nuclear factor 3-gamma

1

2

High-throughput

0.536

High

1056454

IRF3
Interferon regulatory factor 3

1

1

High-throughput

0.536

High

1199083

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

1

High-throughput

0.536

High

1288022

HDA11
Histone deacetylase 11

1

4

High-throughput

0.536

High

1301735

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.536

High

1301740

FOXP3
Forkhead box protein P3

1

3

High-throughput

0.536

High

1301745

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.536

High

1267421

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

1

High-throughput

0.526

High

843860

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.518

High

850154

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

6

High-throughput

0.515

High

1301754

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

3

High-throughput

0.515

High

823220

DPOD2
DNA polymerase delta subunit 2

1

1

Small-scale

0.500

High

1078633

SMAD2
Mothers against decapentaplegic homolog 2

1

0

Small-scale

0.493

High

1301738

OSB10
Oxysterol-binding protein-related protein 10

1

0

High-throughput

0.493

High

1301734

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

337537

ABL1
Tyrosine-protein kinase ABL1

1

0

Small-scale

0.480

High

1038031

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.480

High

1301746

DPOD4
DNA polymerase delta subunit 4

1

0

Small-scale

0.479

High

163172

XPO1
Exportin-1

1

8

High-throughput

0.479

High

200953

ATMIN
ATM interactor

1

1

Small-scale

0.479

High

244820

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

319308

BRD1
Bromodomain-containing protein 1

1

14

High-throughput

0.479

High

385381

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

487699

ANDR
Androgen receptor

1

10

High-throughput

0.479

High

553495

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

600210

TAF1
Transcription initiation factor TFIID subunit 1

1

7

High-throughput

0.479

High

652022

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

668922

PML
Protein PML

1

6

High-throughput

0.479

High

684968

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

749798

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.479

High

750432

COIL
Coilin

1

2

High-throughput

0.479

High

802485

ATRX
Transcriptional regulator ATRX

1

9

Small-scale

0.479

High

1019096

TP53B
TP53-binding protein 1

1

4

High-throughput

0.479

High

1025514

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

Small-scale

0.479

High

1026517

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

1042344

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1188752

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1190069

MAVS
Mitochondrial antiviral-signaling protein

1

9

High-throughput

0.479

High

1198268

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

6

Small-scale

0.479

High

1205119

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

7

High-throughput

0.479

High

1222532

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

1236452

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1239153

ZBT38
Zinc finger and BTB domain-containing protein 38

1

4

Small-scale

0.479

High

1246151

COP1
E3 ubiquitin-protein ligase COP1

1

6

High-throughput

0.479

High

1269421

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

1270393

HDAC2
Histone deacetylase 2

1

2

High-throughput

0.479

High

1288253

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.479

High

1300902

CIC
Protein capicua homolog

1

11

High-throughput

0.479

High

1301742

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

5

Small-scale

0.479

High

1301744

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1301750

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1301751

TLS1
Splicing factor C9orf78

1

3

High-throughput

0.479

High

1301753

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1301757

TRAF6
TNF receptor-associated factor 6

1

2

Small-scale

0.479

High

1301758

ARI1
E3 ubiquitin-protein ligase ARIH1

1

7

High-throughput

0.479

High

135488

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

0

High-throughput

0.458

High

319037

CEP43
Centrosomal protein 43

1

0

Small-scale

0.458

High

660870

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

0

High-throughput

0.458

High

884782

NU107
Nuclear pore complex protein Nup107

1

0

Small-scale

0.458

High

932342

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1014189

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

0

High-throughput

0.458

High

1027209

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1285691

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1297508

PRIPO
DNA-directed primase/polymerase protein

1

0

Small-scale

0.458

High

1301736

EYA3
Eyes absent homolog 3

1

0

High-throughput

0.458

High

1301739

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

1301752

KS6B2
Ribosomal protein S6 kinase beta-2

1

0

High-throughput

0.458

High

1301756

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.458

High

256988

KDM4A
Lysine-specific demethylase 4A

1

9

Small-scale

0.445

High

370256

ESR1
Estrogen receptor

1

10

High-throughput

0.445

High

529605

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.445

High

1130470

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

6

High-throughput

0.445

High

657004

5HT2A
5-hydroxytryptamine receptor 2A

1

2

Small-scale

0.437

High

721222

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

783803

5HT2B
5-hydroxytryptamine receptor 2B

1

2

Small-scale

0.437

High

1101236

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1153902

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.437

High

1165878

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1171340

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1173824

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

1

4

Small-scale

0.437

High

1244444

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.437

High

1260878

DCAF4
DDB1- and CUL4-associated factor 4

1

3

High-throughput

0.437

High

1290033

RNF31
E3 ubiquitin-protein ligase RNF31

1

7

Small-scale

0.437

High

1301737

EPAS1
Endothelial PAS domain-containing protein 1

1

5

Small-scale

0.437

High

1301743

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1301748

NLE1
Notchless protein homolog 1

1

3

High-throughput

0.437

High

1066078

DPOD3
DNA polymerase delta subunit 3

1

0

Small-scale

0.426

High

831615

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.408

High

1079689

ADIPO
Adiponectin

1

0

High-throughput

0.279

Low

352692

TNFA
Tumor necrosis factor

1

0

High-throughput

0.249

Low

441773

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

1239311

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1301755

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024