Protein: TISD
mRNA decay activator protein ZFP36L2 (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (TPA-induced sequence 11d) (Zinc finger protein 36, C3H1 type-like 2) (ZFP36-like 2)

Gene: TISD, ZFP36L2
Organism: Homo sapiens
Interactions: 207
UniProt ID: P47974

Gene Ontology (top 5):
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006402 - mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

729673

1433B
14-3-3 protein beta/alpha

6

17

High-throughput

0.727

High

868998

1433G
14-3-3 protein gamma

5

17

High-throughput

0.718

High

869011

1433Z
14-3-3 protein zeta/delta

5

17

High-throughput

0.712

High

869024

1433F
14-3-3 protein eta

5

17

High-throughput

0.712

High

869001

1433E
14-3-3 protein epsilon

4

1

High-throughput

0.691

High

869089

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

3

1

High-throughput

0.667

High

869067

GEMI5
Gem-associated protein 5

1

0

High-throughput

0.656

High

690822

1433T
14-3-3 protein theta

3

17

High-throughput

0.633

High

172044

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

8

High-throughput

0.618

High

250501

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

5

High-throughput

0.618

High

295113

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

5

High-throughput

0.618

High

550170

PABP1
Polyadenylate-binding protein 1

1

6

High-throughput

0.618

High

576314

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

6

High-throughput

0.618

High

620199

NUCL
Nucleolin

1

6

High-throughput

0.618

High

650638

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

6

High-throughput

0.618

High

655104

SFPQ
Splicing factor, proline- and glutamine-rich

1

6

High-throughput

0.618

High

660553

IF4B
Eukaryotic translation initiation factor 4B

1

5

High-throughput

0.618

High

687350

PTBP1
Polypyrimidine tract-binding protein 1

1

6

High-throughput

0.618

High

868987

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

5

High-throughput

0.618

High

869017

RBM10
RNA-binding protein 10

1

5

High-throughput

0.618

High

869028

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.618

High

869040

NONO
Non-POU domain-containing octamer-binding protein

1

7

High-throughput

0.618

High

869078

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

7

High-throughput

0.618

High

869084

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

7

High-throughput

0.618

High

869101

STRAP
Serine-threonine kinase receptor-associated protein

1

1

High-throughput

0.618

High

869032

CUL3
Cullin-3

2

6

High-throughput

0.611

High

869100

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.586

High

395670

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

869047

FBW10
F-box/WD repeat-containing protein 10

1

2

High-throughput

0.553

High

869064

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.553

High

869090

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

1

High-throughput

0.536

High

730445

1433S
14-3-3 protein sigma

1

17

High-throughput

0.515

High

869076

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.513

High

869033

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.481

High

162499

ANM5
Protein arginine N-methyltransferase 5

1

3

High-throughput

0.479

High

172565

XPO1
Exportin-1

1

5

High-throughput

0.479

High

187913

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

1

High-throughput

0.479

High

240065

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

3

High-throughput

0.479

High

358636

LDHA
L-lactate dehydrogenase A chain

1

2

High-throughput

0.479

High

408725

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.479

High

424021

ITB3
Integrin beta-3

1

1

High-throughput

0.479

High

428323

RLA2
Large ribosomal subunit protein P2

1

1

High-throughput

0.479

High

443709

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

1

High-throughput

0.479

High

445143

S10A6
Protein S100-A6

1

1

High-throughput

0.479

High

445775

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

450951

LDHB
L-lactate dehydrogenase B chain

1

2

High-throughput

0.479

High

549546

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

3

High-throughput

0.479

High

565814

EF2
Elongation factor 2

1

2

High-throughput

0.479

High

568213

PLST
Plastin-3

1

1

High-throughput

0.479

High

584719

NDKA
Nucleoside diphosphate kinase A

1

1

High-throughput

0.479

High

600042

ZNF18
Zinc finger protein 18

1

2

High-throughput

0.479

High

608493

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

High-throughput

0.479

High

656069

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.479

High

755531

TTK
Dual specificity protein kinase TTK

1

5

High-throughput

0.479

High

801217

HSPA9
Stress-70 protein, mitochondrial

1

2

High-throughput

0.479

High

828702

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

861513

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

High-throughput

0.479

High

868993

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

3

High-throughput

0.479

High

868997

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

7

High-throughput

0.479

High

869010

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

869013

TBA1B
Tubulin alpha-1B chain

1

2

High-throughput

0.479

High

869014

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.479

High

869019

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.479

High

869020

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

1

High-throughput

0.479

High

869021

OTUD4
OTU domain-containing protein 4

1

4

High-throughput

0.479

High

869023

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.479

High

869025

PRDX1
Peroxiredoxin-1

1

1

High-throughput

0.479

High

869027

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

5

High-throughput

0.479

High

869030

MB211
Putative nucleotidyltransferase MAB21L1

1

1

High-throughput

0.479

High

869034

CAPR1
Caprin-1

1

2

High-throughput

0.479

High

869035

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

3

High-throughput

0.479

High

869036

PUM1
Pumilio homolog 1

1

4

High-throughput

0.479

High

869038

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

869039

STK38
Serine/threonine-protein kinase 38

1

3

High-throughput

0.479

High

869041

SIX1
Homeobox protein SIX1

1

2

High-throughput

0.479

High

869051

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

869058

UN45B
Protein unc-45 homolog B

1

1

High-throughput

0.479

High

869059

DHX40
Probable ATP-dependent RNA helicase DHX40

1

2

High-throughput

0.479

High

869062

CMYA5
Cardiomyopathy-associated protein 5

1

5

High-throughput

0.479

High

869066

BRSK1
Serine/threonine-protein kinase BRSK1

1

5

High-throughput

0.479

High

869069

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

869071

S10AG
Protein S100-A16

1

1

High-throughput

0.479

High

869072

ZN333
Zinc finger protein 333

1

1

High-throughput

0.479

High

869073

TRI47
E3 ubiquitin-protein ligase TRIM47

1

4

High-throughput

0.479

High

869079

ZFY21
Zinc finger FYVE domain-containing protein 21

1

1

High-throughput

0.479

High

869081

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

3

High-throughput

0.479

High

869082

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.479

High

869085

SYCM
Probable cysteine--tRNA ligase, mitochondrial

1

1

High-throughput

0.479

High

869087

MOV10
Helicase MOV-10

1

3

High-throughput

0.479

High

869088

SPTN5
Spectrin beta chain, non-erythrocytic 5

1

1

High-throughput

0.479

High

869091

OGFR
Opioid growth factor receptor

1

3

High-throughput

0.479

High

869092

DDX20
Probable ATP-dependent RNA helicase DDX20

1

6

High-throughput

0.479

High

869093

XPO7
Exportin-7

1

5

High-throughput

0.479

High

869097

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

1

High-throughput

0.479

High

869098

SIK3
Serine/threonine-protein kinase SIK3

1

2

High-throughput

0.479

High

869105

NS1BP
Influenza virus NS1A-binding protein

1

3

High-throughput

0.479

High

61727

SBNO1
Protein strawberry notch homolog 1

1

0

High-throughput

0.458

High

128851

MEN1
Menin

1

0

High-throughput

0.458

High

138915

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

1

0

High-throughput

0.458

High

167186

IRF6
Interferon regulatory factor 6

1

0

High-throughput

0.458

High

269482

PLCH2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2

1

0

High-throughput

0.458

High

285610

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.458

High

317514

TPPP
Tubulin polymerization-promoting protein

1

0

High-throughput

0.458

High

329709

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

0

High-throughput

0.458

High

391001

TRFL
Lactotransferrin

1

0

High-throughput

0.458

High

428085

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.458

High

446758

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

457301

TBB5
Tubulin beta chain

1

0

High-throughput

0.458

High

459498

PROF1
Profilin-1

1

0

High-throughput

0.458

High

461261

HS90A
Heat shock protein HSP 90-alpha

1

0

High-throughput

0.458

High

484429

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

507666

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

528214

THIO
Thioredoxin

1

0

High-throughput

0.458

High

532442

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

536721

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

570858

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

582707

EZRI
Ezrin

1

0

High-throughput

0.458

High

623182

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

658034

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

659994

COF1
Cofilin-1

1

0

High-throughput

0.458

High

664846

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.458

High

764272

CTNA1
Catenin alpha-1

1

0

High-throughput

0.458

High

770098

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

787930

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

809526

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

821254

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.458

High

837440

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

841647

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

842265

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

860439

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

860660

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.458

High

868986

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

0

High-throughput

0.458

High

868988

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.458

High

868991

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

868994

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

868995

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.458

High

868996

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

868999

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

869000

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.458

High

869002

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.458

High

869003

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

869004

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.458

High

869005

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

869006

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.458

High

869007

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

869008

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

869009

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

869012

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

869022

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

0

High-throughput

0.458

High

869026

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

869031

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

869044

PCID2
PCI domain-containing protein 2

1

0

High-throughput

0.458

High

869045

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.458

High

869050

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.458

High

869053

TLC3B
Ceramide synthase

1

0

High-throughput

0.458

High

869055

CENPQ
Centromere protein Q

1

0

High-throughput

0.458

High

869056

FBX11
F-box only protein 11

1

0

High-throughput

0.458

High

869057

MGAP
MAX gene-associated protein

1

0

High-throughput

0.458

High

869060

ZNF34
Zinc finger protein 34

1

0

High-throughput

0.458

High

869061

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

High-throughput

0.458

High

869065

TET1
Methylcytosine dioxygenase TET1

1

0

High-throughput

0.458

High

869068

HEXD
Hexosaminidase D

1

0

High-throughput

0.458

High

869074

TPPC9
Trafficking protein particle complex subunit 9

1

0

High-throughput

0.458

High

869075

UIF
UAP56-interacting factor

1

0

High-throughput

0.458

High

869077

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.458

High

869080

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.458

High

869083

ZY11B
Protein zyg-11 homolog B

1

0

High-throughput

0.458

High

869094

TEN1
Teneurin-1

1

0

High-throughput

0.458

High

869095

PADI1
Protein-arginine deiminase type-1

1

0

High-throughput

0.458

High

869099

TR150
Thyroid hormone receptor-associated protein 3

1

0

High-throughput

0.458

High

869102

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

869103

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

869104

SETBP
SET-binding protein

1

0

High-throughput

0.458

High

869042

SF01
Splicing factor 1

1

5

High-throughput

0.457

High

869052

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.445

High

131357

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

1

High-throughput

0.437

High

366121

C1R
Complement C1r subcomponent

1

2

High-throughput

0.437

High

369842

CO3
Complement C3

1

1

High-throughput

0.437

High

457953

TRY1
Serine protease 1

1

2

High-throughput

0.437

High

634899

PZP
Pregnancy zone protein

1

1

High-throughput

0.437

High

762221

TRY3
Trypsin-3

1

2

High-throughput

0.437

High

829309

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

869016

IDD
Integral membrane protein DGCR2/IDD

1

1

High-throughput

0.437

High

869037

RB39A
Ras-related protein Rab-39A

1

1

High-throughput

0.437

High

869049

ARSK
Arylsulfatase K

1

1

High-throughput

0.437

High

638173

S1PR1
Sphingosine 1-phosphate receptor 1

1

0

High-throughput

0.426

High

139055

LAD1
Ladinin-1

1

0

High-throughput

0.279

Low

299108

FLOT1
Flotillin-1

1

0

High-throughput

0.249

Low

378671

IGJ
Immunoglobulin J chain

1

0

High-throughput

0.249

Low

437477

CASB
Beta-casein

1

0

High-throughput

0.249

Low

446388

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

712156

TKT
Transketolase

1

0

High-throughput

0.249

Low

790872

TAGL2
Transgelin-2

1

0

High-throughput

0.249

Low

868989

AK1C2
Aldo-keto reductase family 1 member C2

1

0

High-throughput

0.249

Low

868990

GAS1
Growth arrest-specific protein 1

1

0

High-throughput

0.249

Low

868992

MYL6
Myosin light polypeptide 6

1

0

High-throughput

0.249

Low

869015

KGD4
Alpha-ketoglutarate dehydrogenase component 4

1

0

High-throughput

0.249

Low

869018

AT2C1
Calcium-transporting ATPase type 2C member 1

1

0

High-throughput

0.249

Low

869029

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

0

High-throughput

0.249

Low

869043

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

869046

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

0

High-throughput

0.249

Low

869048

LCTL
Lactase-like protein

1

0

High-throughput

0.249

Low

869054

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.249

Low

869063

PRCA1
Protein PROCA1

1

0

High-throughput

0.249

Low

869070

TOP1M
DNA topoisomerase I, mitochondrial

1

0

High-throughput

0.249

Low

869086

S38AA
Solute carrier family 38 member 10

1

0

High-throughput

0.249

Low

869096

PCDA4
Protocadherin alpha-4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025