Protein: KPC1
Protein kinase C-like 1 (PKC 1) (EC 2.7.11.13)

Gene: KPC1, PKC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 119
UniProt ID: P24583

Gene Ontology (top 5):
GO:0000425 - pexophagy
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

419673

RHO1
GTP-binding protein RHO1

11

20

Small-scale

0.979

High

623431

KPC1
Protein kinase C-like 1

2

17

Small-scale

0.767

High

339455

CDK1
Cyclin-dependent kinase 1

1

6

High-throughput

0.724

High

623455

EDE1
EH domain-containing and endocytosis protein 1

1

6

High-throughput

0.691

High

623464

AKL1
Serine/threonine-protein kinase AKL1

1

19

High-throughput

0.691

High

376643

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

6

Small-scale

0.656

High

623442

MKK1
MAP kinase kinase MKK1/SSP32

1

17

Small-scale

0.656

High

623444

PAH1
Phosphatidic acid phosphohydrolase 1

3

1

Small-scale

0.655

High

623494

ZDS2
Protein ZDS2

3

2

Small-scale

0.649

High

614885

KC12
Casein kinase I homolog 2

1

8

High-throughput

0.647

High

623483

FKH2
Fork head protein homolog 2

1

7

Small-scale

0.647

High

623499

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

17

Small-scale

0.647

High

623515

PKH2
Serine/threonine-protein kinase PKH2

1

18

Small-scale

0.647

High

623449

STE5
Protein STE5

1

0

Small-scale

0.645

High

623447

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

2

High-throughput

0.633

High

623438

URA7
CTP synthase 1

3

0

Small-scale

0.627

High

605610

KIN3
Serine/threonine-protein kinase KIN3

1

18

High-throughput

0.621

High

623446

TOR2
Serine/threonine-protein kinase TOR2

2

12

Small-scale

0.602

High

342666

ENO1
Enolase 1

2

3

High-throughput

0.601

High

623497

2ABA
Protein phosphatase PP2A regulatory subunit B

2

6

Small-scale

0.595

High

623435

SYP1
Suppressor of yeast profilin deletion

2

0

Small-scale

0.592

High

365836

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

623432

SIS1
Protein SIS1

1

11

High-throughput

0.575

High

623434

MAS5
Mitochondrial protein import protein MAS5

1

7

High-throughput

0.575

High

623451

HSP78
Heat shock protein 78, mitochondrial

2

3

High-throughput

0.571

High

420085

TOP2
DNA topoisomerase 2

1

7

Small-scale

0.568

High

623480

SSB2
Ribosome-associated molecular chaperone SSB2

2

12

High-throughput

0.552

High

623467

NEM1
Nuclear envelope morphology protein 1

2

3

Small-scale

0.550

High

623463

AP2A
AP-2 complex subunit alpha

1

3

High-throughput

0.536

High

623484

LSB3
LAS seventeen-binding protein 3

1

9

High-throughput

0.536

High

623472

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

1

0

Small-scale

0.529

High

623498

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

6

High-throughput

0.515

High

623509

PIN3
[PSI+] inducibility protein 3

1

10

High-throughput

0.508

High

623453

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

1

Small-scale

0.504

High

623436

RS5
Small ribosomal subunit protein uS7

1

2

Small-scale

0.501

High

623495

H3
Histone H3

1

8

Small-scale

0.501

High

588978

TYR1
Prephenate dehydrogenase [NADP(+)]

1

0

High-throughput

0.493

High

623469

TRM5
tRNA

1

0

High-throughput

0.493

High

623492

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.493

High

623518

FOLD
Dihydrofolate synthetase

1

0

High-throughput

0.493

High

514613

FUS1
Nuclear fusion protein FUS1

1

0

High-throughput

0.486

High

623443

SMI1
Cell wall assembly regulator SMI1

1

0

Small-scale

0.486

High

623479

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.486

High

623490

TOS2
Protein TOS2

1

0

High-throughput

0.486

High

446116

MYO1
Myosin-1

1

10

High-throughput

0.481

High

607205

RFA1
Replication factor A protein 1

1

6

Small-scale

0.481

High

623437

PRP45
Pre-mRNA-processing protein 45

1

2

Small-scale

0.481

High

623450

SLA2
Protein SLA2

1

6

High-throughput

0.481

High

623454

NUF2
Kinetochore protein NUF2

1

4

High-throughput

0.481

High

623456

CASP
Protein CASP

1

12

High-throughput

0.481

High

623459

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.481

High

623470

LAM4
Membrane-anchored lipid-binding protein LAM4

1

4

High-throughput

0.481

High

623473

END3
Actin cytoskeleton-regulatory complex protein END3

1

2

High-throughput

0.481

High

623475

RGA1
Rho-type GTPase-activating protein 1

1

3

High-throughput

0.481

High

623477

LIS1
Nuclear distribution protein PAC1

1

13

High-throughput

0.481

High

623501

MDM1
Structural protein MDM1

1

2

High-throughput

0.481

High

623517

PRP46
Pre-mRNA-splicing factor PRP46

1

12

Small-scale

0.481

High

594090

KICH
Choline kinase

1

0

Small-scale

0.480

High

597561

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

Small-scale

0.480

High

623512

RT109
Histone acetyltransferase RTT109

1

0

Small-scale

0.480

High

623514

NDD1
Nuclear division defective protein 1

1

0

Small-scale

0.480

High

623521

IGO2
mRNA stability protein IGO2

1

0

Small-scale

0.480

High

141171

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

406808

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

407741

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

623439

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

623462

GBLP
Small ribosomal subunit protein RACK1

1

17

High-throughput

0.479

High

623466

KPR2
Ribose-phosphate pyrophosphokinase 2

1

14

High-throughput

0.479

High

623500

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

14

Small-scale

0.479

High

623502

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

623504

ESC1
Silent chromatin protein ESC1

1

3

High-throughput

0.470

High

623486

BBC1
Myosin tail region-interacting protein MTI1

1

3

High-throughput

0.464

High

525770

TOP3
DNA topoisomerase 3

1

0

Small-scale

0.460

High

623440

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.460

High

623460

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.460

High

623471

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.460

High

623481

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

High-throughput

0.460

High

623487

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.460

High

623496

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

623506

VPS20
Vacuolar protein sorting-associated protein 20

1

0

High-throughput

0.460

High

623507

FMP27
Protein FMP27, mitochondrial

1

0

High-throughput

0.460

High

623508

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.460

High

623510

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

623448

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

623458

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

623489

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

623505

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

623511

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

490407

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

493254

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

510333

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

623441

HS104
Heat shock protein 104

1

3

High-throughput

0.445

High

623445

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

623468

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

623474

TCPG
T-complex protein 1 subunit gamma

1

17

High-throughput

0.445

High

623478

HSP7E
Heat shock protein SSC3, mitochondrial

1

17

High-throughput

0.445

High

623461

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

2

High-throughput

0.439

High

623519

VPS5
Vacuolar protein sorting-associated protein 5

1

5

High-throughput

0.439

High

623520

AP2M
AP-2 complex subunit mu

1

4

Small-scale

0.439

High

357896

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

405445

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

413319

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

479937

RS6A
Small ribosomal subunit protein eS6A

1

6

High-throughput

0.437

High

480499

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

623433

BPH1
Beige protein homolog 1

1

5

High-throughput

0.437

High

623452

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

623482

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

Small-scale

0.437

High

623513

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

623485

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

623488

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

623493

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

576169

SPO7
Sporulation-specific protein SPO7

2

0

Small-scale

0.314

High

623503

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

Small-scale

0.288

High

623516

ATG34
Autophagy-related protein 34

1

0

High-throughput

0.279

Low

623457

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

623476

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

623491

SP105
Spindle pole body component SPC105

1

0

High-throughput

0.251

Low

623465

GIP1
GLC7-interacting protein 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024