Protein: SRC8
Src substrate cortactin

Gene: SRC8, Cttn
Organism: Mus musculus
Interactions: 47
UniProt ID: Q60598

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0002102 - podosome
GO:0005522 - profilin binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

59626

A2AM57
Inversin

1

10

High-throughput

0.618

High

204403

CASL
Enhancer of filamentation 1

1

20

Small-scale

0.618

High

811946

ZO1
Tight junction protein 1

1

11

Small-scale

0.618

High

913629

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

1

20

Small-scale

0.586

High

1221190

WASL
Actin nucleation-promoting factor WASL

2

20

Small-scale

0.584

High

723732

CTND1
Catenin delta-1

1

6

Small-scale

0.578

High

663098

GRIA2
Glutamate receptor 2

2

7

Small-scale

0.571

High

771472

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

12

High-throughput

0.536

High

1221184

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

4

High-throughput

0.536

High

1221185

MYOME
Myomegalin

1

14

High-throughput

0.536

High

1221192

ARP3
Actin-related protein 3

1

20

Small-scale

0.536

High

990945

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

6

Small-scale

0.515

High

1221196

HIP1R
Huntingtin-interacting protein 1-related protein

1

16

Small-scale

0.501

High

147957

STXB1
Syntaxin-binding protein 1

1

2

High-throughput

0.479

High

313345

COR1A
Coronin-1A

1

11

High-throughput

0.479

High

753180

MMP2
72 kDa type IV collagenase

1

1

Small-scale

0.479

High

810546

DYN2
Dynamin-2

1

20

Small-scale

0.479

High

927775

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

947688

NPHP4
Nephrocystin-4

1

1

High-throughput

0.479

High

989556

MK01
Mitogen-activated protein kinase 1

1

3

Small-scale

0.479

High

1021526

AURKA
Aurora kinase A

1

7

Small-scale

0.479

High

1021566

RGS14
Regulator of G-protein signaling 14

1

1

High-throughput

0.479

High

1029195

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

12

High-throughput

0.479

High

1064109

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

9

Small-scale

0.479

High

1210156

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

5

High-throughput

0.479

High

1221179

PPP5
Serine/threonine-protein phosphatase 5

1

11

High-throughput

0.479

High

1221180

SC6A4
Sodium-dependent serotonin transporter

1

4

High-throughput

0.479

High

1221181

BRSK2
Serine/threonine-protein kinase BRSK2

1

5

High-throughput

0.479

High

1221182

NEB2
Neurabin-2

1

14

High-throughput

0.479

High

1221191

EED
Polycomb protein EED

1

9

High-throughput

0.479

High

1221194

RBCC1
RB1-inducible coiled-coil protein 1

1

18

Small-scale

0.479

High

1221195

HAKAI
E3 ubiquitin-protein ligase Hakai

1

12

Small-scale

0.479

High

1221198

KCNQ2
Potassium voltage-gated channel subfamily KQT member 2

1

10

High-throughput

0.479

High

1210757

CLU
Clustered mitochondria protein homolog

1

0

High-throughput

0.458

High

1221189

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.458

High

1221188

WIPF1
WAS/WASL-interacting protein family member 1

1

20

Small-scale

0.457

High

948496

ARPC4
Actin-related protein 2/3 complex subunit 4

1

1

Small-scale

0.445

High

958396

ARP2
Actin-related protein 2

1

20

Small-scale

0.445

High

1221193

ARPC2
Actin-related protein 2/3 complex subunit 2

1

2

Small-scale

0.445

High

1221197

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

Small-scale

0.445

High

398449

CFAD
Complement factor D

1

4

High-throughput

0.437

High

1221183

SPOP
Speckle-type POZ protein

1

3

High-throughput

0.437

High

1221186

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

10

High-throughput

0.437

High

1221187

MT21E
Protein-lysine methyltransferase METTL21E

1

3

High-throughput

0.437

High

683098

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.436

High

771703

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.407

High

1021690

THIOM
Thioredoxin, mitochondrial

1

5

High-throughput

0.407

High


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Last updated: 11Aug2025