Protein: FAK1
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)

Gene: FAK1, Ptk2
Organism: Mus musculus
Interactions: 38
UniProt ID: P34152

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0001525 - angiogenesis
GO:0001568 - blood vessel development
GO:0001570 - vasculogenesis
GO:0001764 - neuron migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757463

PAXI
Paxillin

6

20

Small-scale

0.928

High

431327

SRC
Proto-oncogene tyrosine-protein kinase Src

4

20

Small-scale

0.873

High

757456

BCAR1
Breast cancer anti-estrogen resistance protein 1

3

20

Small-scale

0.860

High

757443

FYN
Tyrosine-protein kinase Fyn

2

20

Small-scale

0.743

High

757455

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.695

High

757454

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

20

High-throughput

0.691

High

757457

DLG4
Disks large homolog 4

1

20

High-throughput

0.691

High

757459

EFS
Embryonal Fyn-associated substrate

2

20

Small-scale

0.686

High

757440

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.647

High

205456

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.618

High

547743

L1CAM
Neural cell adhesion molecule L1

1

8

Small-scale

0.618

High

686932

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.618

High

757441

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

Small-scale

0.618

High

757442

DYN2
Dynamin-2

1

17

Small-scale

0.618

High

757445

EPHB2
Ephrin type-B receptor 2

1

20

Small-scale

0.618

High

757452

EPS8
Epidermal growth factor receptor kinase substrate 8

1

20

Small-scale

0.618

High

757458

SRBS1
Sorbin and SH3 domain-containing protein 1

1

20

Small-scale

0.618

High

757469

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.618

High

757444

TIA1
Cytotoxic granule associated RNA binding protein TIA1

2

4

Small-scale

0.584

High

757449

GRB7
Growth factor receptor-bound protein 7

1

20

Small-scale

0.575

High

757467

DLGP1
Disks large-associated protein 1

2

13

High-throughput

0.558

High

757462

MEF2C
Myocyte-specific enhancer factor 2C

1

0

Small-scale

0.549

High

757460

HDAC4
Histone deacetylase 4

1

18

High-throughput

0.536

High

757451

GATA4
Transcription factor GATA-4

1

1

Small-scale

0.501

High

108486

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

522152

BCL2
Apoptosis regulator Bcl-2

1

3

Small-scale

0.479

High

648034

MYD88
Myeloid differentiation primary response protein MyD88

1

14

Small-scale

0.479

High

757446

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

High-throughput

0.479

High

757447

ELAV1
ELAV-like protein 1

1

6

Small-scale

0.479

High

757448

NRP1
Neuropilin-1

1

7

Small-scale

0.479

High

757450

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

15

Small-scale

0.479

High

757453

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

757461

WDTC1
WD and tetratricopeptide repeats protein 1

1

19

High-throughput

0.479

High

757464

WASL
Actin nucleation-promoting factor WASL

1

20

Small-scale

0.479

High

757465

ARP3
Actin-related protein 3

1

8

Small-scale

0.479

High

757466

LPXN
Leupaxin

1

20

Small-scale

0.479

High

757468

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

17

Small-scale

0.479

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025