Protein: P5CR
Pyrroline-5-carboxylate reductase (P5C reductase) (P5CR) (EC 1.5.1.2)

Gene: P5CR, PRO3
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P32263

Gene Ontology (top 5):
GO:0004735 - pyrroline-5-carboxylate reductase activity
GO:0005737 - cytoplasm
GO:0006561 - proline biosynthetic process
GO:0042802 - identical protein binding
GO:0055129 - L-proline biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686880

P5CR
Pyrroline-5-carboxylate reductase

3

14

High-throughput

0.856

High

686893

COPB2
Coatomer subunit beta'

3

2

High-throughput

0.611

High

490595

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.552

High

510557

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

686890

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

686899

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

686900

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

686910

MEX67
mRNA export factor MEX67

1

0

High-throughput

0.518

High

627583

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.493

High

342681

ENO1
Enolase 1

1

2

High-throughput

0.479

High

365950

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

543363

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

680506

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

686887

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

686898

HST2
NAD-dependent protein deacetylase HST2

1

3

High-throughput

0.479

High

686881

EF2
Elongation factor 2

1

3

High-throughput

0.470

High

686892

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.470

High

608453

SAN1
Protein SAN1

1

0

Small-scale

0.460

High

141212

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

340062

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

340636

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

406873

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

482138

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

631731

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

686884

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

686888

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

686896

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

686897

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

686901

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

686902

COFI
Cofilin

1

0

High-throughput

0.458

High

686904

POC1
Proteasome chaperone 1

1

0

High-throughput

0.458

High

686905

SGO1
Shugoshin

1

0

High-throughput

0.458

High

686909

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

477988

HSP77
Import motor subunit, mitochondrial

1

3

High-throughput

0.445

High

493417

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

628931

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.445

High

686883

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

334898

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.437

High

342887

ENO2
Enolase 2

1

2

High-throughput

0.437

High

470923

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

638671

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

686908

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.437

High

360787

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

367835

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

555881

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

686895

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

686891

JEM1
DnaJ-like chaperone JEM1

1

5

High-throughput

0.407

High

686882

EI2BB
Translation initiation factor eIF2B subunit beta

2

0

High-throughput

0.326

High

686894

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.305

High

420243

CALM
Calmodulin

1

0

Small-scale

0.292

High

474257

NFT1
ABC transporter NFT1

1

0

High-throughput

0.282

High

686886

ATX1
Copper chaperone ATX1

1

0

High-throughput

0.282

High

686889

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.269

Low

686906

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

474280

YK104
Putative uncharacterized protein YKR104W

1

0

High-throughput

0.251

Low

343564

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.249

Low

357944

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383008

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

389377

HXKB
Hexokinase-2

1

0

High-throughput

0.249

Low

425821

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

472074

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

520937

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

645315

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

661581

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

686885

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

686903

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

686907

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024