Protein: RIO2
Serine/threonine-protein kinase RIO2 (EC 2.7.11.1)

Gene: RIO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P40160

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

770069

TSR1
Ribosome biogenesis protein TSR1

15

4

Small-scale

0.981

High

644903

RS5
Small ribosomal subunit protein uS7

9

3

Small-scale

0.962

High

631912

RS2
Small ribosomal subunit protein uS5

5

4

Small-scale

0.906

High

481784

RS16B
Small ribosomal subunit protein uS9B

3

5

Small-scale

0.827

High

770080

RS25A
Small ribosomal subunit protein eS25A

3

4

Small-scale

0.827

High

748622

ENP1
Essential nuclear protein 1

16

4

Small-scale

0.761

High

770071

NOB1
20S-pre-rRNA D-site endonuclease NOB1

14

4

Small-scale

0.758

High

770040

DIM1
Dimethyladenosine transferase

13

2

Small-scale

0.757

High

770083

PNO1
Pre-rRNA-processing protein PNO1

13

3

Small-scale

0.757

High

479349

RS23B
Small ribosomal subunit protein uS12B

2

2

Small-scale

0.754

High

770076

RIO1
Serine/threonine-protein kinase RIO1

2

3

High-throughput

0.754

High

664469

HRR25
Casein kinase I homolog HRR25

8

1

Small-scale

0.749

High

407087

RS3
Small ribosomal subunit protein uS3

10

3

Small-scale

0.748

High

480701

RS8A
Small ribosomal subunit protein eS8A

8

4

Small-scale

0.741

High

413537

RS14A
Small ribosomal subunit protein uS11A

7

4

Small-scale

0.736

High

770057

RS15
Small ribosomal subunit protein uS19

7

3

Small-scale

0.736

High

709371

LTV1
Protein LTV1

15

0

Small-scale

0.727

High

141364

RS9A
Small ribosomal subunit protein uS4A

6

4

Small-scale

0.726

High

358093

RS17A
Small ribosomal subunit protein eS17A

6

4

Small-scale

0.726

High

407949

RS13
Small ribosomal subunit protein uS15

6

3

Small-scale

0.726

High

700447

RSSA1
Small ribosomal subunit protein uS2A

6

7

Small-scale

0.726

High

479754

RS4A
Small ribosomal subunit protein eS4A

6

3

Small-scale

0.719

High

706303

RS3A1
Small ribosomal subunit protein eS1A

6

6

Small-scale

0.719

High

470750

RS21A
Small ribosomal subunit protein eS21A

5

5

Small-scale

0.709

High

425984

RS19A
Small ribosomal subunit protein eS19A

5

5

Small-scale

0.702

High

480135

RS6A
Small ribosomal subunit protein eS6A

5

4

Small-scale

0.702

High

482290

RS18A
Small ribosomal subunit protein uS13A

5

3

Small-scale

0.702

High

645476

RS7A
Small ribosomal subunit protein eS7A

5

5

Small-scale

0.702

High

752486

RS20
Small ribosomal subunit protein uS10

5

3

Small-scale

0.702

High

770046

RS12
Small ribosomal subunit protein eS12

5

2

Small-scale

0.702

High

770078

RRP12
Ribosomal RNA-processing protein 12

4

2

Small-scale

0.691

High

471087

RS22A
Small ribosomal subunit protein uS8A

4

4

Small-scale

0.676

High

481517

RS11B
Small ribosomal subunit protein uS17B

4

4

Small-scale

0.676

High

742826

GBLP
Small ribosomal subunit protein RACK1

4

6

Small-scale

0.676

High

613706

RS3A2
Small ribosomal subunit protein eS1B

4

6

Small-scale

0.674

High

765628

BEM2
GTPase-activating protein BEM2/IPL2

3

3

High-throughput

0.671

High

471506

RS28B
Small ribosomal subunit protein eS28B

3

5

Small-scale

0.656

High

761896

RS14B
Small ribosomal subunit protein uS11B

3

4

Small-scale

0.646

High

407533

RS9B
Small ribosomal subunit protein uS4B

3

4

Small-scale

0.640

High

426299

RS19B
Small ribosomal subunit protein eS19B

3

5

Small-scale

0.640

High

634628

KRR1
KRR1 small subunit processome component

3

2

Small-scale

0.640

High

729943

RS27A
Small ribosomal subunit protein eS27A

3

3

Small-scale

0.640

High

765228

RS26B
Small ribosomal subunit protein eS26B

3

3

Small-scale

0.640

High

770038

RS29A
Small ribosomal subunit protein uS14A

3

3

Small-scale

0.640

High

770042

RSSA2
Small ribosomal subunit protein uS2B

3

7

Small-scale

0.640

High

770044

RS7B
Small ribosomal subunit protein eS7B

3

5

Small-scale

0.640

High

770072

RS10A
Small ribosomal subunit protein eS10A

3

5

Small-scale

0.640

High

770079

RS21B
Small ribosomal subunit protein eS21B

3

5

Small-scale

0.640

High

770081

RS28A
Small ribosomal subunit protein eS28A

3

5

Small-scale

0.640

High

603315

SNF2
Transcription regulatory protein SNF2

2

6

High-throughput

0.621

High

676098

XPO1
Exportin-1

2

7

Small-scale

0.619

High

470668

RS25B
Small ribosomal subunit protein eS25B

1

4

Small-scale

0.618

High

770036

RIO2
Serine/threonine-protein kinase RIO2

1

3

Small-scale

0.618

High

770049

SLX9
Ribosome biogenesis protein SLX9

3

0

Small-scale

0.613

High

770082

RS22B
Small ribosomal subunit protein uS8B

2

4

Small-scale

0.611

High

770048

EIF2A
Eukaryotic translation initiation factor 2A

3

2

High-throughput

0.604

High

577158

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

2

3

High-throughput

0.588

High

696148

SWI3
SWI/SNF complex subunit SWI3

2

3

High-throughput

0.588

High

408380

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

2

4

Small-scale

0.584

High

479481

RS24A
Small ribosomal subunit protein eS24A

2

3

Small-scale

0.584

High

535234

RS17B
Small ribosomal subunit protein eS17B

2

4

Small-scale

0.584

High

765185

RS26A
Small ribosomal subunit protein eS26A

2

3

Small-scale

0.584

High

770039

RS29B
Small ribosomal subunit protein uS14B

2

3

Small-scale

0.584

High

415992

DED1
ATP-dependent RNA helicase DED1

1

7

Small-scale

0.536

High

534775

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.536

High

550049

CSK21
Casein kinase II subunit alpha

1

9

High-throughput

0.536

High

584744

CSK22
Casein kinase II subunit alpha'

1

6

High-throughput

0.536

High

757941

CSK2C
Casein kinase II subunit beta'

1

4

High-throughput

0.536

High

760572

SSN3
Meiotic mRNA stability protein kinase SSN3

1

5

High-throughput

0.536

High

770037

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

4

High-throughput

0.536

High

770041

CSK2B
Casein kinase II subunit beta

1

4

High-throughput

0.536

High

770045

ASK10
Activator of SKN7 protein 10

1

4

High-throughput

0.536

High

770052

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.536

High

770066

BFR2
Protein BFR2

1

1

High-throughput

0.536

High

770077

DBP10
ATP-dependent RNA helicase DBP10

1

12

High-throughput

0.536

High

755823

LSM12
Protein LSM12

1

0

High-throughput

0.513

High

770050

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.513

High

565621

PHO85
Cyclin-dependent protein kinase PHO85

1

3

High-throughput

0.501

High

614673

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.501

High

698824

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

Small-scale

0.501

High

770067

TSR2
Pre-rRNA-processing protein TSR2

1

0

High-throughput

0.493

High

383179

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

399494

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.479

High

405655

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.479

High

479606

RS30A
Small ribosomal subunit protein eS30A

1

1

Small-scale

0.479

High

498951

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.479

High

526248

KIN2
Serine/threonine-protein kinase KIN2

1

3

High-throughput

0.479

High

535012

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

536292

CPYI
Carboxypeptidase Y inhibitor

1

2

Small-scale

0.479

High

593761

DBP5
ATP-dependent RNA helicase DBP5

1

9

Small-scale

0.479

High

624105

DBP2
ATP-dependent RNA helicase DBP2

1

6

High-throughput

0.479

High

662369

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

680750

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

696507

TOR2
Serine/threonine-protein kinase TOR2

1

5

High-throughput

0.479

High

710887

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.479

High

740851

YC16
UPF0743 protein YCR087C-A

1

2

High-throughput

0.479

High

753006

RS27B
Small ribosomal subunit protein eS27B

1

3

Small-scale

0.479

High

753533

OTU2
OTU domain-containing protein 2

1

1

High-throughput

0.479

High

759360

STM1
Suppressor protein STM1

1

1

High-throughput

0.479

High

762248

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

764960

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

770043

RS10B
Small ribosomal subunit protein eS10B

1

5

High-throughput

0.479

High

770053

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

770056

NOP3
Serine/arginine

1

9

High-throughput

0.479

High

770059

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

770061

RGC1
Regulator of the glycerol channel 1

1

4

High-throughput

0.479

High

770068

YL419
Putative ATP-dependent RNA helicase YLR419W

1

6

High-throughput

0.479

High

770074

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

5

High-throughput

0.479

High

770075

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.479

High

770084

MEX67
mRNA export factor MEX67

1

1

Small-scale

0.479

High

450449

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

602447

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

630206

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

710704

MTR2
mRNA transport regulator MTR2

1

0

Small-scale

0.458

High

768005

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.458

High

770047

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.458

High

770051

PXR1
Protein PXR1

1

0

High-throughput

0.458

High

770060

AVO2
Target of rapamycin complex 2 subunit AVO2

1

0

High-throughput

0.458

High

770062

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

770063

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

High-throughput

0.458

High

770064

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

770065

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

770070

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.458

High

746575

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.457

High

382754

RL24A
Large ribosomal subunit protein eL24A

1

2

Small-scale

0.445

High

424548

PYR1
Multifunctional protein URA2

1

4

High-throughput

0.445

High

511510

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

519950

TCPA
T-complex protein 1 subunit alpha

1

5

High-throughput

0.445

High

705237

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

746995

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

4

Small-scale

0.445

High

757388

IF1A
Eukaryotic translation initiation factor 1A

1

2

Small-scale

0.445

High

768557

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

770058

HAS1
ATP-dependent RNA helicase HAS1

1

13

High-throughput

0.445

High

427372

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

1

High-throughput

0.437

High

770054

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

1

4

High-throughput

0.437

High

770055

NUM1
Nuclear migration protein NUM1

1

6

High-throughput

0.437

High

770073

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

753498

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.279

Low

701220

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024