Protein: Q60I23
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)

Gene: Q60I23, Sox2
Organism: Mus musculus
Interactions: 48
UniProt ID: Q60I23

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001649 - osteoblast differentiation
GO:0001654 - eye development
GO:0001714 - endodermal cell fate specification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1049111

SOX8
Transcription factor SOX-8

1

20

High-throughput

0.575

High

1180429

Q2TBA9
SRY

1

18

High-throughput

0.575

High

1222158

TF7L1
Transcription factor 7-like 1

1

19

High-throughput

0.575

High

59403

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

20

High-throughput

0.554

High

1222137

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.536

High

60010

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.484

High

107466

F8WHY8
Metastasis associated 1

1

20

High-throughput

0.484

High

148695

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.484

High

478349

HXA5
Homeobox protein Hox-A5

1

20

High-throughput

0.484

High

949046

RUVB1
RuvB-like 1

1

7

High-throughput

0.484

High

1000011

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.484

High

1021778

SMRC1
SWI/SNF complex subunit SMARCC1

1

20

High-throughput

0.484

High

1022004

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.484

High

1221125

SIN3A
Paired amphipathic helix protein Sin3a

1

8

High-throughput

0.484

High

1222059

RBBP4
Histone-binding protein RBBP4

1

19

High-throughput

0.484

High

1222087

RBBP7
Histone-binding protein RBBP7

1

20

High-throughput

0.484

High

1222136

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

High-throughput

0.484

High

1222141

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

20

High-throughput

0.484

High

1222155

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.484

High

1222156

RUVB2
RuvB-like 2

1

7

High-throughput

0.484

High

1222159

MBD3
Methyl-CpG-binding domain protein 3

1

7

High-throughput

0.484

High

1222160

ACL6A
Actin-like protein 6A

1

5

High-throughput

0.484

High

688464

TWST1
Twist-related protein 1

1

10

High-throughput

0.445

High

871808

RFX3
Transcription factor RFX3

1

3

High-throughput

0.445

High

1222138

NACC1
Nucleus accumbens-associated protein 1

1

20

High-throughput

0.445

High

1222140

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.445

High

1222144

CCAR2
Cell cycle and apoptosis regulator protein 2

1

7

High-throughput

0.445

High

1222145

ZNF24
Zinc finger protein 24

1

11

High-throughput

0.445

High

1222147

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.445

High

1222149

MTREX
Exosome RNA helicase MTR4

1

19

High-throughput

0.445

High

1222150

SALL1
Sal-like protein 1

1

17

High-throughput

0.445

High

1222153

SALL2
Sal-like protein 2

1

17

High-throughput

0.445

High

1222154

DNJA2
DnaJ homolog subfamily A member 2

1

5

High-throughput

0.445

High

1222157

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

4

High-throughput

0.445

High

51271

A1L3S7
GATA zinc finger domain containing 2B

1

12

High-throughput

0.442

High

62733

A4QPD1
Zinc finger E-box-binding homeobox 1

1

12

High-throughput

0.442

High

67961

A7UQY4
Heterogeneous nuclear ribonucleoprotein M

1

6

High-throughput

0.442

High

107246

F8VQL9
Nuclear receptor corepressor 2

1

20

High-throughput

0.442

High

921211

CUX1
Homeobox protein cut-like 1

1

20

High-throughput

0.442

High

1222135

SALL3
Sal-like protein 3

1

17

High-throughput

0.442

High

1222139

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.442

High

1222142

P66A
Transcriptional repressor p66 alpha

1

12

High-throughput

0.442

High

1222148

SP16H
FACT complex subunit SPT16

1

5

High-throughput

0.442

High

1222151

XPO4
Exportin-4

1

7

High-throughput

0.442

High

717012

TEAD1
Transcriptional enhancer factor TEF-1

1

4

High-throughput

0.407

High

1222143

DOCK7
Dedicator of cytokinesis protein 7

1

1

High-throughput

0.407

High

1222146

Q91YZ2
C-terminal-binding protein 2

1

8

High-throughput

0.407

High

1222152

Q9JM08
Histone deacetylase

1

20

High-throughput

0.407

High


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Last updated: 11Aug2025